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  • 1
    Monograph available for loan
    Monograph available for loan
    Agrarumweltpolitik nach dem Subsidiaritätsprinzip : Ziele, Ordungsrahmen und instrumentelle Alternativen (2000)
    Berlin : Analytica
    Associated volumes
    Details Availability
    Call number: PIK W 021-01-0201
    In: Schriften zur Agrarforschung und Agrarpolitik
    Type of Medium: Monograph available for loan
    Pages: 182 S.
    Edition: 1. Aufl.
    ISBN: 3929342553
    Series Statement: Schriften zur Agrarforschung und Agrarpolitik 2
    Branch Library: PIK Library
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  • 2
    Electronic Resource
    Electronic Resource
    Solvent-induced linkage isomerizations (1971)
    s.l. : American Chemical Society
    Inorganic chemistry 10 (1971), S. 2032-2038 
    Details
    ISSN: 1520-510X
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ic50103a039
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  • 3
    Electronic Resource
    Electronic Resource
    Note on the Molecular Structure of 1,2,4,5-Tetrabromocyclohexane (m. p. 185°) (1939)
    s.l. : American Chemical Society
    Journal of the American Chemical Society 61 (1939), S. 1601-1602 
    Details
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ja01875a505
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  • 4
    Electronic Resource
    Electronic Resource
    Preparation and Properties of Ultra Thin Anodic Valve Metal Oxide Films (1995)
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 185-188 (Mar. 1995), p. 581-590 
    Details
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/02/01/transtech_doi~10.4028%252Fwww.scientific.net%252FMSF.185-188.581.pdf
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  • 5
    Electronic Resource
    Electronic Resource
    The level of expression of a protein kinase C gene may be an important component of the patterning process in Hydra (1998)
    Springer
    Development genes and evolution 207 (1998), S. 502-514 
    Details
    ISSN: 1432-041X
    Keywords: Key words Hydra ; Hydrozoa ; Protein kinase C ; nPKC ; Regeneration
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract  Several studies have provided strong, but indirect evidence that signalling through pathways involving protein kinase C (PKC) plays an important role in morphogenesis and patterning in Hydra. We have cloned a gene (HvPKC2) from Hydra vulgaris which encodes a member of the nPKC subfamily. In adult polyps, HvPKC2 is expressed at high levels in two locations, the endoderm of the foot and the endoderm of the hypostomal tip. Increased expression of HvPKC2 is an early event during head and foot regeneration, with the rise in expression being restricted to the endodermal cells underlying the regenerating ends. No upregulation is observed if regenerates are cut too close to the head to form a foot. Elevated expression of HvPKC2 is also observed in the endoderm underlying lithium-induced ectopic feet. A dynamic and complex pattern of expression is seen in developing buds. Regeneration of either head or foot is accompanied by an increase in the amount of PKC in both soluble and particulate fractions. An increase in the fraction of PKC activity which is membrane-bound is specifically associated with head regeneration. Taken together these data suggest that patterning of the head and foot in Hydra is controlled in part by the level of HvPKC2 expression, whilst head formation is accompanied by an in vivo activation of both calcium-dependent and independent PKC isoforms.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004270050141
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  • 6
    Electronic Resource
    Electronic Resource
    Lithium ions interfere with pattern control in Hydra vulgaris (1990)
    Springer
    Development genes and evolution 198 (1990), S. 382-388 
    Details
    ISSN: 1432-041X
    Keywords: Hydra vulgaris ; Pattern control ; Lithium ; Foot formation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary LiCl in concentrations exceeding 0.5 mM affects morphogenesis in Hydra vulgaris (formerly named H. attenuata) by interfering with the foot-forming system(s). Pulse treatment of Hydra bearing small buds or of animals that develop a bud within 14 h after the end of treatment prevented foot formation at the bud's base in a concentration-dependent manner. With increasing concentrations of Li+ or length of treatment in increasing percentage of the buds remained permanently connected to the parent by a bridge of tissue thus forming a stable secondary axis. Instead of the normal ring-shaped foot a patch of basal disc tissue developed or the bud failed to differentiate foot tissue at all. Long-term culture of animals in 1 mM LiCl inhibited budding from the second day of treatment onwards and detachment of existing buds was delayed. After 4 days of treatment 15%–30% of budless or bud-bearing animals developed up to three patch-like basal discs at various positions along the body axis; these usually grew out one above the other on the same side of the animal but never at the same transverse level. Besides these patch feet broad belts of foot tissue were observed in the lower gastric region. After 1 week of treatment half of the animals developed a constriction located usually in the lower two-thirds of the body axis. The tissue adjacent to this constriction and particularly above it differentiated into mucus-secreting foot tissue. Subsequent separation into two morphologically intact polyps occurred occasionally. When treatment was stopped, budding restarted within the next 3 days at several positions along the body axis whether or not secondary feet or a constriction existed. Buds grew out in different budding zones, which persisted for several days. This burst of budding led to up to 7 buds per animal within 3 days. After about 1 week the animals regulated to normality or became epithelial, i.e. they lost their stem cells during and after treatment.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00376156
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  • 7
    Electronic Resource
    Electronic Resource
    Expression of HvRACK1, a member of the RACK1 subfamily of regulatory WD40 proteins in Hydra vulgaris, is coordinated between epithelial and interstitial cells in a position-dependent manner (1997)
    Springer
    Development genes and evolution 206 (1997), S. 435-446 
    Details
    ISSN: 1432-041X
    Keywords: Key words Hydrozoa ; Hydra ; RACK1 ; WD-repeat proteins
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract  A gene encoding a member of the growing family of regulatory WD-repeat proteins has been identified in Hydra vulgaris. About 80% of its deduced amino acids are identical to RACK1, which has recently been identified in rat as a receptor for activated C kinase. The presence of a consensus sequence believed to be important for interaction with protein kinase C, prompted us to term the new sequence HvRACK1 (Hydra vulgaris RACK1). In situ hybridization revealed an abundant message restricted to 80% of the body column with the strongest signal in the upper body half. Terminally differentiated structures (foot, tentacles and apicalmost hypostomal cells) were completely free of expression. A corresponding prepattern was established in bisected animals at least 10 h before the regenerating structure began to form. In normal animals HvRACK1 transcripts were contained mainly in interstitial cells (i-cells), gland cells and digestive epithelial cells. Depletion of i-cells and their derivatives by hydroxyurea (HU) treatment induced expression of the gene in epithelio-muscular and -digestive cells with the overall expression level remaining stable as confirmed by northern blotting. Polyps consisting almost exclusively of epithelial cells expressed HvRACK1 differentially along the body axis with a maximum in the head (except tentacles and the apicalmost ectoderm of the hypostome) and fading out towards the foot. The enhanced expression level in epithelial cells of HU-treated animals indicates that these might take over regionspecific HvRACK1 functions usually inherent to interstitial cells and certain derivatives of this lineage.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004270050073
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  • 8
    Electronic Resource
    Electronic Resource
    Upregulation of a Hydra vulgaris cPKC gene is tightly coupled to the differentiation of head structures (1998)
    Springer
    Development genes and evolution 207 (1998), S. 489-501 
    Details
    ISSN: 1432-041X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract  Two different cDNA clones from Hydra (HvPKC1a and HvPKC1b) were characterized, which encode members of the cPKC family of protein kinase Cs (PKCs). The two predicted proteins differ only in their amino-terminal sequences and thus probably represent the products of alternatively spliced mRNAs from a single gene. In situ hybridization with a probe recognizing sequences in common between the two mRNAs detects HvPKC1 RNA in all parts of the adult polyp except the foot. The mRNA is contained in ecto- and endodermal epithelial cells as well as a certain subset of gland cells and pairs of interstitial cells. During head and foot formation, induced by either regeneration, budding, lithium treatment or repeated application of a diacylglycerol, HvPKC1 expression is upregulated immediately prior to the evagination of tentacles and downregulated by foot formation. Although PKC activity is clearly inducible in vitro by diacylglycerol and a tumour promoting phorbol ester, structural features detected in the regulatory domains of HvPKC1a and 1b indicate that endogenous activators for Hydra PKC might differ from those of other organisms. The results corroborate the hypothesis that signal transduction systems using protein kinase C are key elements controlling the formation of head structures in Hydra.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004270050140
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  • 9
    Electronic Resource
    Electronic Resource
    Nerve cell and nematocyte production in Hydra is deregulated by lithium ions (1988)
    Springer
    Development genes and evolution 197 (1988), S. 471-475 
    Details
    ISSN: 1432-041X
    Keywords: Nerve cells ; Nematocytes ; Commitment ; Deregulation ; Lithium chloride
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary LiCl, a well-known vegetalising agent, interferes with the commitment of stem cells to nerve cells and nematocytes in Hydra attenuata. Treatment with 20 mM LiCl inhibits commitment to nerve cells, treatment with 1 mM LiCl inhibits commitment to nematocytes. However, LiCl does not prevent stem cells committed to the nematocyte pathway from dividing and differentiating into nests of nematocytes. Following LiCl treatment, determination to nerve cells and nematocytes is triggered again. Commitment to nerve cells is strongly stimulated within the first 3 h following pulse treatment with LiCl if the animals have been fed immediately prior to treatment. In Hydra exposed to LiCl for 10 days the stem cell density is reduced by at least 90% of the initial value, and nematocytes are almost completely missing, whereas the density of nerve cells is within the normal range in animals with normal morphology. Animals which developed a transverse constriction in the middle of the body axis contain a 1.7-fold higher nerve cell density in the lower part than is observed in control animals.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00385680
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  • 10
    Electronic Resource
    Electronic Resource
    Coherent elastic and rotationally inelastic scattering of N2, O2, and CH4 from a 10 K Cu(111) surface (2000)
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 113 (2000), S. 9262-9267 
    Details
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: We report observations of coherent elastic and rotationally inelastic scattering of N2, O2, and CH4 from a 10 K Cu(111) surface, kept clean by pulsed laser heating. The related sharp features in the measured angular distributions decrease drastically in intensity at elevated target temperatures. At low temperature rotational transitions reduce the elastic scattering probability by about an order of magnitude. This effect is weak for D2 at the impact conditions of concern. Quantum scattering calculations for N2 and D2 show that this difference is primarily caused by the large difference in rotational constants and the associated rotational transition energies of these molecules. © 2000 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1319519
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