Publication Date:
2015-06-14
Description:
Article Stress induces ligand-independent endocytosis of EGF receptor (EGFR), but its fate and role in signalling are not known. Here Tomas et al . show that stress-internalized EGFR accumulates and is retained in distinct multivesicular bodies, and delays the onset of stress-induced apoptosis. Nature Communications doi: 10.1038/ncomms8324 Authors: Alejandra Tomas, Simon O. Vaughan, Thomas Burgoyne, Alexander Sorkin, John A. Hartley, Daniel Hochhauser, Clare E. Futter
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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