To regard to dramatic decreasing of pelagic fish and depending on fish meal for sturgeon Feeding a project with title on "Study of possibility of replacement of fish meal by poultry by product in formulated diet of Huso huso" in two faz (fingerling) and (Growth out) were carried out. In first faz, proximate composition of fish meal, poultry by product and diet ingredient were determined , thereafter Six test diets (contain 45% protein and 19 Mj kg^-1 energy) were prepared based on anchovy fish meal and poultry by-product substituted at levels of 20% (PBM_20), 40% (PBM_40), 60% (PBM_60), 80% (PBM_80) and 100% (PBM_100), respectively. Huso huso Fingerlings (28.42±0.17gr ± SD) were stocked in 18 fiberglass tanks and fed to satiation to eight week. Result indicated the highest final weight (FW), Weight gain (WG), Specific growth rate (SGR) and Protein efficiency ratio (PER) were belonged to control diet (350.52 ±21.86_gr),(1133.00 ±74.84%),(3.74±0.092 %per day) and (1.58 ±0.017) respectively. But No significant difference was detected between FM, PBM_20, PBM_40 and PBM_60 (P〉0.05), Also, there were not significant difference in treatments for Feed efficiency Ratio between (PBM_0), (PBM_20), (PBM_40), (PBM_60) (PBM_80) respectively (P〈0.05).But elimination of fish meal (PBM_100) led to significant increase in whole body protein (P〈0.05). In second faz (growth out period), Number of 180 Huso huso (107.89±5.19_gr ± SD) were stocked in 18 fiberglass tanks (volume 2000 lit) and fed by diets contain (40% protein and 20 Mj kg^-1 energy)that poultry by-product substituted at levels of 20% (PBM_20), 40% (PBM_40), 60% (PBM_60), 80% (PBM_80) and 100% (PBM_100) to satiation to 128 days. Biometry carried out one month interval. In the end of nutrition period highest final weight (FW) (844.2 ±2.44_gr), Weight gain (WG) (673.44 ±4.79 %) and Specific growth rate (SGR) (1.59 ±0.047% per day) were observed in fish fed control diet, but no significant differences were detected between (PBM_0), (PBM_20), (PBM_40), (PBM_60) and (PBM_80) respectively (P〉0.05).The best feed efficiency ratio belonged to fish fed PBM_40 that no significant differences with (PBM_20), (PBM_60) and (PBM_80) (P〉0.05).a significant decrease of body lipid observed by increasing of supplementation of poultry by product in diets that lowest body lipid (6.6±0.16) were stabilized in (PBM_80) (P〈0.05). the highest body protein belonged to fish fed PBM_20 (16.67±0.67) that significantly higher than body protein of fish fed PBM_60 (15.41±0.67) (P〈0.05), but no difference compare with other treatments (P〉0.05). also hepatosomatc index were significantly increase by increasing of poultry by product in diets respectively that highest were observed in fish fed PBM100 (4.2±0.63) (P〈0.05).Result of this investigation indicated that poultry by product had high potential for replacing of fish meal in fingerling and growth out Huso huso diet. Therefore suggested a investigation design for research about the effect of poultry by product on growth rate, body composition and immune system of Huso huso at long period for introduce a new replacer product Instead Of fish meal in sturgeon aquaculture industry.
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