Wiley InterScience Backfile Collection 1832-2000
Chemistry and Pharmacology
Two new rotaxane types, the rotaxanes 12a,b and the rotaxane 13, have been synthesised by treating the “axle” 7 with the stopper component 9 in the presence of the “wheel” 8. A nonionic template intermediate of type 10 is proposed. The rotaxane 13 was only obtained when the chain of the “axle” had a certain length: with n = 1 only rotaxane 12 a was isolated, whereas with n = 2 the rotaxane 13 was formed besides the rotaxane 12 b. This suggests that more extended rotaxanes and polyrotaxanes can be synthesised by the template strategy.
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