ALBERT

All Library Books, journals and Electronic Records Telegrafenberg

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
Collection
Keywords
  • 1
    facet.materialart.
    Unknown
    PANGAEA
    In:  Supplement to: Galíndo-Zaldívar, Jesús; Puga, E; Bohoyo, Fernando; González, F J; Maldonado, Andrés; Martos, Yasmina M; Pérez, L F; Ruano, Patricia; Schreider, Anatoly A; Somoza, Luis; Suriñach, Emma; Diaz de Frederico, A (2014): Magmatism, structure and age of Dove Basin (Antarctica): A key to understanding South Scotia Arc development. Global and Planetary Change, 122, 50-69, https://doi.org/10.1016/j.gloplacha.2014.07.021
    Publication Date: 2023-08-28
    Description: Dove Basin is situated in the south-central Scotia Sea, between Pirie and Bruce banks, and was formed during the development of the Scotia Arc. The basin has a roughly sigmoidal shape, with a prominent NNE?SSW elongated ridge located in its central part, the Dove Ridge, which is considered as an extinct spreading axis. A NE?SW elongated tectonic high, the Dove Seamount, is located in the north-eastern region of the basin, bounded by a normal fault dipping to the southeast. Dredged rocks and geophysical data were collected during the SCAN2004 and SCAN2008 cruises. Dredged samples were recovered from three positive features in the center of the basin, two from Dove Ridge, and one from Dove Seamount. Igneous rocks along the Dove Ridge are mainly tholeiitic basalts, derived from asthenospheric upper mantle within an extensional supra-subduction back-arc tectonic setting, which evolved over time from back-arc basin basalts (BABB) toward Mid Oceanic Ridge Basalts (MORBs). Altered olivine-bearing fine- and medium-grained basaltic rocks were also dredged from Dove Ridge and the seamount, together with minor oceanic island arc basalts and basaltic andesites. The mantle source was affected, up to early Miocene times, by a subducted oceanic slab related to an arc to the east, with Dove Basin forming in a back-arc position. Minor alkaline oceanic island basalts dredged at the seamount might represent a final extensional stage, genetically related with the dying Dove Ridge volcanism or, less probably, to a later, late Miocene?Pliocene extensional stage, producing incipient volcanism deriving from a deeper mantle source. 40Ar/39Ar dating of MORB samples dredged from the Dove Ridge provided ages of 20.4 ± 2.6 to 22.8 ± 3.1 Ma. These outcrops were later coated by Fe?Mn crusts with Co-Chronometer ages ranging from at least 12.6 Ma and probably up to 18 Ma. Analysis of magnetic anomaly profiles shows the best fit in the central profile, corresponding to chrons C6B (21.7 Ma) to C7 (24.5 Ma), although alternative ages may be proposed due to the short length. This interpretation supports the 40Ar/39Ar dating of a late Oligocene to early Miocene age. The spreading was asymmetrical, the asynchronous age of extinction of spreading in the basin being confirmed by the variable character of magnetic anomalies. The western part extended faster than the eastern part, suggesting an eastward location for a westward deepening subduction zone. The age obtained for the Dove Basin is older than the age previously proposed for the Protector Basin located to the west, thus suggesting an opposite polarity for the development of some small oceanic basins of the southern Scotia Sea with respect to others generated by an eastward migrating arc over subducted Atlantic oceanic floor. This apparent contradiction could be explained by considering the Dove Basin as originated from an Oligocene to early Miocene arc?back-arc spreading system, which would contribute to the eastward general development of the Scotia Arc, meanwhile Protector Basin was formed by a middle Miocene extensional phase, not genetically related with the main oceanic spreading along the Dove Basin.
    Keywords: Dredge; DRG; Hespérides; NOAA and MMS Marine Minerals Geochemical Database; NOAA-MMS; SCAN2004; SCAN2004-DA2; Scotia Sea
    Type: Dataset
    Format: application/zip, 2 datasets
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 2
    Publication Date: 2023-08-28
    Keywords: Deposit type; DEPTH, sediment/rock; Description; Dredge; DRG; File name; Hespérides; Identification; NOAA and MMS Marine Minerals Geochemical Database; NOAA-MMS; Position; Quantity of deposit; SCAN2004; SCAN2004-DA2; Scotia Sea; Sediment type; Size; Substrate type; Uniform resource locator/link to image; Visual description
    Type: Dataset
    Format: text/tab-separated-values, 10 data points
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 3
    Publication Date: 2023-08-28
    Keywords: Aluminium oxide; Arsenic; Barium; Calcium oxide; Cerium; Cobalt; Copper; Deposit type; DEPTH, sediment/rock; Dredge; DRG; Dysprosium; Erbium; Europium; Gadolinium; Hespérides; Holmium; Identification; Inductively coupled plasma - mass spectrometry (ICP-MS); Iron oxide, Fe2O3; Lanthanum; Lead; Loss on ignition; Lutetium; Magnesium oxide; Manganese oxide; Molybdenum; Neodymium; Nickel; NOAA and MMS Marine Minerals Geochemical Database; NOAA-MMS; Phosphorus pentoxide; Potassium oxide; Praseodymium; Samarium; SCAN2004; SCAN2004-DA2; Scotia Sea; Silicon dioxide; Sodium oxide; Strontium; Terbium; Thallium; Thulium; Titanium dioxide; Vanadium; Wet chemistry; X-ray fluorescence (XRF); Ytterbium; Zinc
    Type: Dataset
    Format: text/tab-separated-values, 38 data points
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 4
    ISSN: 1520-4995
    Source: ACS Legacy Archives
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 5
    ISSN: 1520-4995
    Source: ACS Legacy Archives
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 6
    ISSN: 1432-1432
    Keywords: Cytochrome P450 ; CYP2A ; CYP2B ; CYP2F ; Gene family ; Tandem duplication
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Cytochrome P450 genes from the CYP2A, CYP2B, and CYP2F subfamilies form a tight cluster which we have localized on the detailed physical map of human chromosome 19. The corresponding three gene subfamilies are also clustered in the mouse genome, on the region of chromosome 7 known to be syntenic to human chromosome 19. One hundred eight cosmid clones from the human P450 region were assembled into a single contig of 350 kb, restriction mapped, and probed with cDNAs from the three gene subfamilies. A total of 11 genes were identified in humans, including five from the 2A subfamily, three from the 2B subfamily, and three from the 2F subfamily; at least six of the 11 are pseudogenes. The organization of the genes, with members of the three subfamilies intermixed, indicates that the evolution of this gene cluster has been complex. The modern gene arrangement in humans is probably the result of a series of tandem duplications, plus at least one inverted duplication. The identification of all genes and pseudogenes in this cluster also makes it possible to determine the origins of some previously known variant P450 transcripts.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 7
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 52 (1997), S. 293-298 
    ISSN: 1432-1041
    Keywords: Key words Naproxen ; Cytochrome P450; human liver microsomes ; vaccinia virus ; cDNA expression
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Abstract Objective: A series of studies was undertaken to determine the cytochrome P450 isoform(s) involved in naproxen demethylation and whether this included the same isoforms reported to be involved in the metabolism of other NSAIDs. Methods: (S)-Naproxen was incubated with human liver microsomes in the presence of a NADPH-generating system and the formation of desmethylnaproxen was measured by high-performance liquid chromatography (HPLC). To further clarify the specific isoforms involved, experiments were conducted with preparations expressing only a single P450 isoform (vaccinia virus-expressed cells and microsomes derived from a lymphoblastoid cell line, each transfected with specific P450 cDNAs) as well as inhibition studies using human liver microsomes and putative specific P450 inhibitors. Results: In human liver microsomes (n=7), desmethylnaproxen formation was observed with a mean kM of 92 (21) μmol · l−1, Vmax of 538 pmol · min−1 · mg−1 protein and Cint2 (reflective of a second binding site) of 0.36 μl · min−1 · mg−1 protein. This Cint2 term was added since Eadie-Scatchard analysis suggested the involvement of more than one enzyme. Studies using putative specific P450 inhibitors demonstrated inhibition of this␣reaction by sulfaphenazole, (apparent Ki= 1.6 μmol · l−1), warfarin (apparent Ki=27 μmol · l−1), piroxicam (apparent Ki=23 μmol · l−1) and tolbutamide (apparent Ki=128 μmol · l−1). No effect was observed when α-naphthoflavone and troleandomycin were employed as inhibitors, but reaction with furafylline produced, on average, a maximum inhibition of 23%. At a naproxen concentration of 150 μmol · l−1, formation of desmethylnaproxen was observed in cells expressing P450 1A2, 2C8, 2C9 and its allelic variant 2C9R144C. To further characterize these reactions, saturation kinetics experiments were conducted for the P450s 1A2, 2C8 and 2C9. The kM and Vmax for P450 1A2 were 189.5 μmol · l−1 and 7.3 pmol · min−1 · pmol−1 P450, respectively. Likewise, estimates of kM and Vmax for P450 2C9 were 340.5 μmol · l−1 and 41.4 pmol · min−1 · pmol−1 P450, respectively. Reliable estimates of kM and Vmax could not be made for P450 2C8 due to the nonsaturable nature of the process over the concentration range studied. Conclusion: Multiple cytochrome P450 isoforms (P450 1A2, 2C8 and 2C9) appear to be involved in naproxen demethylation, although 2C9 appears to be the predominant form.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 8
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 40 (1991), S. 415-416 
    ISSN: 1432-1041
    Keywords: Enterocolitis ; loperamide ; necrosing ; case report ; perforation ; adverse reaction
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary Two cases of necrotising enterocolitis with perforation occurred in patients with paralytic ileus after loperamide therapy. The possible role of loperamide in the pathogenesis of the complications is suggested.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 9
    Electronic Resource
    Electronic Resource
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Pharmacology 35 (1995), S. 369-390 
    ISSN: 0362-1642
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Medicine , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 10
    Electronic Resource
    Electronic Resource
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Biochemistry 56 (1987), S. 945-993 
    ISSN: 0066-4154
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Chemistry and Pharmacology , Biology
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...