Springer Online Journal Archives 1860-2000
Chemistry and Pharmacology
Summary The growth of strains ofE. coli is inhibited in the early stages by several complex anions of cobalt(III). All of these contain chelating (chel) dicarboxylate ligands (propane-1, 3-dioate, ethane-1, 2-dioate, or carbonate)e.g. K3[Co(mal)3]3H2O where mal denotes the dianion of propane-1, 3-dioic acid, but most of them also contain unidentate pyridines,e.g. K[Co(chel)2(Rpy)2]nH2O. Among the most active arecis- andtrans-K[Co(mal)2(py)2] hydrates. The effects are distinct from those known for compounds of platinum,e.g. cis-[Pt(NH3)2Cl2] and rhodium,e.g. trans-[Rh(C5H5N)4Cl2]Cl·6H2O.
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