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  • 1
    Publication Date: 2023-10-05
    Description: To help the National Reconnaissance Office (NRO) become more flexible and agile in an increasingly uncertain world, RAND sought answers to two key questions: Would the NRO benefit from building modular satellites? What lessons might be drawn from how chief executive officers, military personnel, and health care professionals (among others) respond to surprise?
    Keywords: Technology ; Business ; History ; bic Book Industry Communication::K Economics, finance, business & management::KJ Business & management::KJC Business strategy ; bic Book Industry Communication::H Humanities::HB History::HBJ Regional & national history::HBJK History of the Americas ; bic Book Industry Communication::T Technology, engineering, agriculture::TR Transport technology & trades::TRP Aerospace & aviation technology
    Language: English
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  • 2
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    RAND Corporation
    Publication Date: 2024-03-30
    Description: This report relates what professionals believe creates surprise, how they respond to it, and how the effects of surprise can be mitigated. RAND researchers interviewed representatives from 13 diverse professions and identified some common coping strategies, such as relying on past experience and trying to reduce the level of chaos in the environment.
    Keywords: Management & Organizational Behavior ; Sociology ; Business ; thema EDItEUR::K Economics, Finance, Business and Management::KJ Business and Management::KJM Management and management techniques ; thema EDItEUR::K Economics, Finance, Business and Management::KJ Business and Management::KJC Business strategy ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBF Social and ethical issues::JBFF Social impact of disasters / accidents (natural or man-made)
    Language: English
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  • 3
    Publication Date: 2023-10-05
    Description: A qualitative analysis of the factors that impede the translation of comparative effectiveness research (CER) into clinical practice and those that facilitate it. Case studies of five recent CER studies are used to explore the extent to which these factors led to changes in clinical practice. The root causes for the failure of translation are synthesized, and policy options to optimize the impact of future CER are proposed.
    Keywords: Health Sciences ; bic Book Industry Communication::M Medicine::MB Medicine: general issues::MBQ Medicolegal issues ; bic Book Industry Communication::M Medicine::MB Medicine: general issues::MBG Medical equipment & techniques::MBGR Medical research ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine
    Language: English
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  • 4
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of the American Chemical Society 107 (1985), S. 7696-7700 
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 38 (1982), S. 824-826 
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Triethyltin (TET) and acetazolamide (ACTZ) both produce marked anticonvulsant effects as evaluated by the maximal electroshock seizure test. However, the mechanism responsible for the anticonvulsant effect of TET and ACTZ is probably not the same since TET does not inhibit the activity of carbonic anhydrase isozyme C in vitro.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Marine biology 35 (1976), S. 149-153 
    ISSN: 1432-1793
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The intertidal polychaete Euzonus mucronata (Treadwell) is found in great numbers within beach sands that undergo periodic anoxia. Short-term exposures (2 to 4 h) to anaerobicity are withstood through the use of a supply of oxyhemoglobin to support continued aerobic metabolism. Longer periods of environmental anoxia activate an anaerobic metabolism capable of sustaining life for up to 20 days, and characterized by the excretion of succinate and propionate. These two mechanisms appear to be adaptations to the variations in occurrence and duration of anoxia within the intertidal sands inhabited by E. mucronata.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Chromosoma 19 (1966), S. 300-316 
    ISSN: 1432-0886
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Irradiation of embryo cells of Schistocerca gregaria in the two hours before mitotic anaphase produces a characteristic series of responses. An apparently insensitive stage is followed by the production of “stickiness” and side-arm bridges and finally by mitotic delay. Mitotic delay is complete at doses as low as 25 R. It is argued that “stickiness’ is due to a generalised physiological process and that side-arm bridges are due to a localised exchange of discrete sub-units of the chromatid. These conclusions are based upon the kinetics of appearance and dose-response and a comparison of haploid and diploid cells in a haplo-diploid mosaic embryo.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Chromosoma 20 (1966), S. 173-194 
    ISSN: 1432-0886
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The structure and frequency of chromatid interchange types in C-metaphase cells of embryos of Schistocerca gregaria are described at the first mitosis following irradiation at the G 2 stage of interphase. The relationship between the different interchange types and the organisation of the interphase nucleus is discussed. It is concluded that most chromatid interchanges are induced between polarised chromosomes though the occurrence of loops and to a lesser extent of terminal overlapping may subsequently modify the appearance of these aberrations at metaphase.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Chromosoma 20 (1967), S. 386-412 
    ISSN: 1432-0886
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Irradiation of Schistocerca gregaria embryo cells during the S and G2 stages of interphase produces the same general classes of chromatid aberration as have been seen in organisms, such as Vicia faba, which have been used widely in radiocytological work. In addition, however, a series of intrachange aberrations has been found which is novel. In order to account for these Revell's exchange hypothesis has been extended to include the involvement of isolocus primary lesions. The exchange-type hypothesis is preferred because it can more readily accomodate the whole spectrum of aberrations found.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Chromosoma 20 (1967), S. 413-441 
    ISSN: 1432-0886
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The variation in yield and the dose-response for chromatid aberration types following x-irradiation of Schistocerca gregaria embryo cells is described. Marked variations in yield are found for all aberration types during the G2 and latter part of S stages of interphase. Only gaps appear to follow similar curves, other aberration types having unique patterns of response. The dose exponents for the various chromatid aberration types are similar to, but lower than, those reported for other organisms. Chromatid “breaks” appear to have a dose exponent greater than 1.0 — a fact which is in conformation with the exchange hypothesis. The chromosome radiosensitivity of this organism is similar to that reported for other organisms.
    Type of Medium: Electronic Resource
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