ISSN:
0018-019X
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Lewis acids catalyze teh condensation of methyl pyruvate and l-naphtol to give menthyl 2-hydroxy-2-(l-hydroxy-2-naphtyl)propionate in a ratio of up 96:4 in favor of the levorotatory diastereoisomer. Epimerization, at 25°C for five days, occurs on benzylic carbon atom to give a 30:70 mixture enriched with the dextrorotatory isomer.
Additional Material:
1 Tab.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/hlca.19840670313
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