ISSN:
1434-4475
Keywords:
Keywords. Potentiometry; Glycine; Cephalosporins; Complexes.
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Summary. The interaction of Ca(II), Cu(II), Zn(II), Pb(II), and La(III) ions with the antibiotics cephalexin, cefadroxil, cephaloridine, and cefoperazone as secondary ligands was investigated potentiometrically. The formation constants were determined for a ligand-to-metal ratio of 1:1 at 25°C and KNO3. The protonation constants of the complexes were evaluated for the system . The order of stability of the binary and ternary complexes were examined. It was found that glycine adds preferably [M(II)-cephalosporin] rather than to the aqueous complexes of M(II). In all cases 1:1:1 complexes were formed.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/s007060070034
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