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  • 1
    Electronic Resource
    Electronic Resource
    A Totally Sex-linked Gene in the House Mouse (1952)
    [s.l.] : Nature Publishing Group
    Nature 169 (1952), S. 664-665 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The new gene is semi-dominant and behaves in every way as would be expected of a totally sex-linked gene with no homologue on the F-chromo-some, though the numbers of mice bred are not yet enough to detect minor deviations from expectation. There are three phenotypes in females,-corre-sponding to ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/169664b0
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  • 2
    Electronic Resource
    Electronic Resource
    Inheritance of Susceptibility to Induced Pulmonary Tumours in Mice (1961)
    [s.l.] : Nature Publishing Group
    Nature 191 (1961), S. 1070-1071 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] THE inheritance of cancer susceptibility is not amenable to study by the methods of Mendelian genetics, because many genes are involved which cannot be recognized individually, and any measure of the degree of susceptibility is subject also to non-genetic variation1. The methods of quantitative ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/1911070a0
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  • 3
    Electronic Resource
    Electronic Resource
    Early Selection Experiments (1992)
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Genetics 26 (1992), S. 1-16 
    Details
    ISSN: 0066-4197
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Biology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1146/annurev.ge.26.120192.000245
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  • 4
    Electronic Resource
    Electronic Resource
    A New Mutant in the Progeny of Mice Treated with Nitrogen Mustard (1949)
    [s.l.] : Nature Publishing Group
    Nature 163 (1949), S. 678-679 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] THE ability of the mustard compounds to induce gene mutations and chromosome re-arrangements was first detected in experiments with Drosophila melanogaster1–3. Subsequent investigators showed that this ability extends to all organisms which so far have been tested : ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/163678a0
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  • 5
    Electronic Resource
    Electronic Resource
    Total sex-linkage in the house mouse (1953)
    Springer
    Molecular genetics and genomics 85 (1953), S. 210-219 
    Details
    ISSN: 1617-4623
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Description / Table of Contents: Zusammenfassung 1. Tabby (Ta) ist ein völlig geschlechtsgebundenes Gen in der Hausmaus. In Weibchen zeigt es unvollkommene Dominanz. Männchen mit dieser Mutante gleichen homozygoten Weibchen, ein Beweis, daß das Y-Chromosom kein homologes Gen enthält. 2. Heterozygote Weibchen haben schwarze Querstreifen, die nur auf Agouti-Hintergrund erkennbar sind. Homozygote Weibchen und hemizygote Männchen zeigen eine Anzahl von Abnormitäten, die genau den von dem recessiven Autosomalfaktor crinkled hervorgerufenen gleichen. 3. Brindled und Mottled sind gleichfalls völlig geschlechtsgebunden; das geht hervor aus Koppelungsversuchen mit Weibchen, die heterozygot für Tabby und eines dieser Gene sind. Sowohl Brindled und Mottled haben Tabby gegenüber eine Rekombinationshäufigkeit von ungefähr 4%. Das beweist das Vorkommen von crossing-over in dem Differentialsegment des X-Chromosoms in Weibchen.
    Notes: Summary 1. A totally sex-linked gene, Tabby (Ta), in the house mouse is described. It is semi-dominant in females. Mutant males resemble homozygous females, which shows that there is no homologue on the Y-chromosome. 2. Heterozygous females have transverse black markings, visible only in agoutis. Homozygous females and hemizygous males have a number of defects exactly resembling those produced by the autosomal recessive crinkled. 3. Brindled and Mottled are shown also to be totally sex-linked, by means of linkage tests with Tabby in doubly heterozygous females. Both Brindled and Mottled recombine with Tabby with a frequency of about 4%. This proves that crossing-over takes place in the differential segment of the X-chromosome in females.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00309836
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  • 6
    Electronic Resource
    Electronic Resource
    Linkage in the mouse: The sex-linked genes and “rough” (1954)
    Springer
    Molecular genetics and genomics 86 (1954), S. 263-268 
    Details
    ISSN: 1617-4623
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Description / Table of Contents: Zusammenfassung Die Reihenfolge der total geschlechtsgebundenen Gene und ihre Rekombinationshäufigkeit in heterozygoten Weibchen ist $$B_n - 11\% - Ta - 4\% - _{Mo}^{Br} $$ \ Rough (ro) liegt in Koppelungsgruppe V, zwischen pa und Sd und sehr dicht bei pa. Die Rekombinationshäufigkeit zwischen pa und ro ist ungefähr 0,6%.
    Notes: Summary The order of the totally sex-linked genes and the recombination frequencies in heterozygous females are — $$B_n - 11\% - Ta - 4\% - \left\{ {_{Mo}^{Br} } \right\}$$ Rough (ro) is located in linkage Group V, between pa and Sd and very close to pa. Recombination frequency between pa and ro is about 0.6%.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00444792
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  • 7
    Electronic Resource
    Electronic Resource
    Dreher, ein neues Gen der Tanzmausgruppe bei der Hausmaus (1951)
    Springer
    Molecular genetics and genomics 84 (1951), S. 71-73 
    Details
    ISSN: 1617-4623
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Zusammenfassung Es wurde ein neues Gen der Tanzmausgruppe beschrieben mit den Symptomen Hyperaktivität, Kopfschütteln und Tanzen und Taubheit. Die Abnormalität trat bei 4 Jungen in einem Wurf freilebender wilder Hausmäuse auf, mit größter Wahrscheinlichkeit spontan. Kreuzungsversuche zeigten, daß die Abnormität durch ein rezessives Gen mit vollständiger Penetranz verursacht wird. Die neue Mutation ist nicht identisch mit v, sh-1, sh-2, je, kr, pi oder fi. English Summary. A new gene with the typical phenotype of the waltzer-shaker group is described. The name dreher, with symbol dr, is proposed. It arose, presumably by spontaneous mutation, in the wild, and was obtained in a litter of four, all of which were homozygotes, captured in a factory in Detmold, Germany. The gene is recessive and good single-factor segregations were obtained. Non-identity with v, sh-1, sh-2, je, kr, pi, and fi was proved.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00309744
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  • 8
    Electronic Resource
    Electronic Resource
    Selection for environmental variability of body size in mice (1956)
    Springer
    Molecular genetics and genomics 87 (1956), S. 385-391 
    Details
    ISSN: 1617-4623
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary 1. An experiment with mice is described which was intended to show whether the degree of sensitivity to environmental influences can be changed by selection of extreme phenotypic deviants for a metric character. 2. Body weight was taken as a metric character and opposite extremes (large × small) were selected as parents in the “extreme” line. Individuals closest to the mean were selected as parents in the “central” line. The coefficient of variation of body weight was followed through 13 generations of this selection. 3. No change of variability was detected in the extreme line. The males, but not the females, of the central line showed a small decline of variability. 4. The two lines diverged in body weight in both sexes in the second half of the experiment, the extreme line being the heavier. The cause of this difference is not known. 5. The conclusion to which the results point is that selection of extreme phenotypic deviants did not materially change the sensitivity to environmental influences. An increase in environmental variance from this cause is therefore unlikely to be an important consequence of unidirectional selection.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00737158
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  • 9
    Electronic Resource
    Electronic Resource
    Growth regulation in chimaeras between large and small mice (1976)
    [s.l.] : Nature Publishing Group
    Nature 260 (1976), S. 244-245 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Aggregation chimaeras were made, by methods described previously1, between mice from strains selected for large (L) and small (S) body size, and between L and unselected control (C) mice; the history of the strains is given in ref. 2. Some C??C chimaeras are included for comparison. Fifty overt ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/260244a0
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  • 10
    Electronic Resource
    Electronic Resource
    White Plumage of Sea-Birds (1944)
    [s.l.] : Nature Publishing Group
    Nature 153 (1944), S. 777-777 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] IN recent correspondence, Craik1 has suggested that the white plumage of gulls and some other sea-birds might be an advantage to them by rendering them less visible to the fish on which they prey. This interpretation was questioned by Pirenne and Crombie2, partly ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/153777a0
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