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  • 1
    Keywords: Bioethics. ; Medicine Research. ; Biology Research. ; Biomedical engineering. ; Medical sciences. ; Drug development. ; Clinical medicine Research. ; Environment. ; Bioethics. ; Biomedical Research. ; Biomedical Engineering and Bioengineering. ; Preclinical Research. ; Clinical Research. ; Environmental Sciences.
    Description / Table of Contents: Foreword - Peter Singer -- Introduction: Biomedical Research in One World: Current and Future Challenges -- Part I - Biomedical Research -- Section One - Genetic and Cell Research -- Chap 1: Learning from Icarus: The Impact of CRISPR on Gene Editing Ethics -- Chap 2: Bioethical Decision Making and Genome Editing -- Chap 3: Therapeutic Genome Editing -- Chap 4: Bioethical Decision-Making about Somatic Cell Genome Editing: Sickle-Cell Disease as a Case Study -- Chap 5: Gene Therapy and Germline Cells Research -- Chap 6: Bioethical Quandaries in Preimplantation Genetic Diagnosis -- Chap 7: Rare Disease Research -- Chap 8: Limits of Debate: Governance of Human Embryo Research and the Making of the Fourteen-Day Rule -- Chap 9 Human/Non-Human Chimeras -- Chap 10: Human Cloning: Recent Advances and Bioethical Issues -- Section Two - Enhancement Research -- Chap 11: The Evolutionary Optimality Challenge -- Chap 12: Mood Enhancement -- Chap 13: Superior Sport Performance: Ethical and Legal Issues -- Chap 14: Arguments over Life Extension in Contemporary Bioethics -- Section Three - Research with Human Biological Samples and Health Data -- Chap 15: Research with Human Biological Samples. Systematization of the Phases and Affected Rights -- Chap 16: Biobanks for Biomedical Research: Evolution and Future -- Chap 17: Biobanking in Global Health & Research -- Chap 18: Ethical and Legal Considerations in Genomic Data Sharing: Evolution of the Discourse and the Road Ahead -- Section Four - Biomedical Challenges in Research -- Chap 19: Human Challenge Trials in Pandemics: Risks and Benefits -- Chap 20: Ethical Considerations for Vaccine Research -- Chap 21: Global Health Partnerships and Emerging Infectious Disease -- Chap 22: Precision Medicine -- Chap 23: The Development, Implementation, and Oversight of Artificial -- Intelligence in Health Care: Legal and Ethical Issues -- Part II - Animals, Food and Environment -- Section One - Using Animals in Scientific Research -- Chap 24: The Use of Animals in Basic Biological Research -- Chap 25: The Use of Animals in the Study of Human Disease: Key Roles of General Ethical Principles -- Chap 26: Ethical Issues Concerning Genetically Modified Animals for the Study of Human Diseases -- Chap 27: Of Mice-Rats and Pig-Men: Ethical Issues in the Development of Human/Nonhuman Chimeras -- Chap 28: Animals in Research in Pharmaceutical Industry -- Chap 29: Animal Use in Toxicity Studies -- Chap 30: Ethical Issues from the Use of Animals in the Cosmetics and Fashion Industries -- Chap 31: Is it Time to Phase Out the Use of all Nonhuman Primates in Invasive Research? -- Chap 32: Growing Human Organs Inside Animals -- Chap 33: Animal Cloning -- Section Two - Decision Making and Alternatives to Animal Use in Research -- Chap 34: Replacement, Reduction and Refinement -- Chap 35: Integrating Human and Nonhuman Research Ethics -- Chap 36: Regulation of Animal Research -- Section Three - GMOs for Global Challenges -- Chap 37: Ethical Issues in Genetically Modified Foods: From Transgenesis to CRISPR-Cas9 Genome Editing Technology -- Chap 38: GMOs and Human and Environmental Safety -- Chap 39: GMOs and Sustainable Agriculture.
    Abstract: The Handbook of Bioethical Decisions is aimed at addressing and analyzing the most important ethical concerns and moral quandaries arisen in biomedical and scientific research. As such, it identifies and problematizes on a comprehensive range of ethical issues researchers must deal with in different critical contexts. Thus, the Handbook, Vol. I, may be helpful for them to make decisions and deliberate in complex practical scenarios. In this fashion, the volume reunites different points of view to give readers room enough to get a better knowledge and take their own position on pressing bioethical issues of the day. Consequently, this work seeks to engender dense ethical epistemology scientists can count on when conducting latest generation biomedical research. By bringing together an impressive array of contributions on the most important elements and categories for “at the bench” bioethical decisions as well as offering chapters by some of the most world renowned and prominent experts in bioethics, the Handbook, Vol. I, is a paradigmatic text in its area and a valuable resource for courses on bioethics, and biomedical research, as well as courses that discuss ethics and the biosciences at different professional levels, biomedical industry, pharmacological companies and the public sphere in general. .
    Type of Medium: Online Resource
    Pages: XX, 778 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031294518
    Series Statement: Collaborative Bioethics, 2
    DDC: 174.2
    Language: English
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  • 2
    Keywords: Bioethics. ; Medicine Research. ; Biology Research. ; Science Moral and ethical aspects. ; Normativity (Ethics). ; Bioethics. ; Biomedical Research. ; Science Ethics. ; Normative Ethics.
    Description / Table of Contents: Foreword: On Handbooks -- Introduction -- Scientific Integrity and Institutional Ethics: Challenges and Perspectives -- Part I - Research Ethics -- Section One - Scientific Integrity and Research Misconduct -- Chap 1: Data Alteration -- Chap 2: Research Misconduct and Questionable Research Practices -- Chap 3: Ethics of Authorship -- Chap 4: Dissemination of Research Results -- Chap 5: Conflicts of Interest in Research -- Chap 6: A Priori Publication Agreements to Improve Adherence to Ethics in Research Publications -- Section Two - Conducting Ethical Research -- Chap 7: Freedom of Scientific Research and Primacy of Human Being: Practical and Epistemological Tensions -- Chap 8: Exploitation in Biomedical Research -- Chap 9: Selection of Research Subjects: Methodological and Ethical Issues -- Chap 10: Confidentiality and Privacy in Digital Clinical Trials -- Chap 11: Dematerialization and Intellectual Property in the Biosciences -- Part II - Institutional Ethics and Bioethics Committees -- Section One - Institutional Ethics -- Chap 12: Historical Development of Institutional Ethics and Bioethics -- Chap 13: Principles of Institutional Ethics -- Chap 14: Institutional Review Boards (IRB): US Perspectives -- Chap 15: Decision Making within Institutions -- Chap 16: Scientific Advances, Ethical Oversight and Legal Institutionality -- Section Two - Ethics and Bioethics Committees -- Chap 17: Members and Structure of Institutional Bioethics Committees -- Chap 18: Foundations of Bioethical Decision-Making in Bioethics and Biolaw -- Chap 19: Just Doing Bioethics': Policy, Principle, and Process -- Chap 20: Ethics Education and Institutional Ethics Committees -- Chap 21: Role of Ethics Committees in Emergency Use of Unproven Interventions Outside Research -- Chap 22: The Ethics of Resource Allocation in Pandemics: A Bayesian Model -- Section Three - Bioethical Issues in Institutional Ethics -- Chap 23: Scientific Knowledge and Social Responsibility -- Chap 24: Conscientious Objection -- Chap 25: Institutional Liability in Research -- Chap 26: Research Assessments Should Recognize Responsible Research Practices. Narrative Review of a Lively Debate and Promising Developments -- Chap 27: Coercion in Mental Health Treatment.
    Abstract: The Handbook of Bioethical Decisions Volume II addresses and analyzes the most important ethical concerns and moral quandaries related to scientific integrity and institutional ethics. It counts on two parts, Part One: Research Ethics, which addresses issues related to Scientific Integrity, Research Misconduct and Conducting Ethical Research, and Part Two: Institutional Ethics and Bioethics Committees, which explores Institutional Ethics issues, Ethics and Bioethics Committees’ roles and scopes, and Bioethical Issues in Institutional Ethics. Consequently, the Handbook, Vol. II, offers a remarkable collection of works by outstanding international experts on institutional and research ethics, in order for bioethics practitioners to obtain better elements to address key issues related to integrity in research as well as to decision-making processes. In this fashion, this volume is a valuable resource for professionals working on different bioethical and biomedical fields, such as, ethics and bioethics committees, health care institutions, biomedical and pharmacological companies, and academic settings, among others. Chapter 26 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
    Type of Medium: Online Resource
    Pages: XVIII, 487 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031294556
    Series Statement: Collaborative Bioethics, 3
    DDC: 174.2
    Language: English
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  • 3
    Monograph available for loan
    Monograph available for loan
    Berkeley, Calif. : Apress
    Call number: 18/M 07.0267
    Type of Medium: Monograph available for loan
    Pages: XXXIV, 559 S. , Ill., graph. Darst.
    ISBN: 1590594959
    Series Statement: The expert's voice in networking
    Classification:
    Informatics
    Location: Reading room
    Branch Library: GFZ Library
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  • 4
    Monograph available for loan
    Monograph available for loan
    Stockholm : Dep. of Geodesy, the royal Institute of Technology
    Call number: M 14.0034
    Type of Medium: Monograph available for loan
    Pages: 31 S. : graph. Darst.
    Series Statement: TRITIA GEOD Report; 1014
    Location: Lower compact magazine
    Branch Library: GFZ Library
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  • 5
    Publication Date: 2023-03-13
    Description: Book chapters with investigations of Theory of the State on the cultures of ancient Peru, carried out by teachers and students of the Professional School of Law of the National University of the Altiplano of Puno.
    Description: Published
    Description: Capítulos de libro con investigaciones de Teoría del Estado sobre las culturas del Perú antiguo, realizado por docentes y estudiantes de la Escuela Profesional de Derecho de la Universidad Nacional del Altiplano de Puno.
    Keywords: Cultura ; Perú ; teoría del estado ; bic Book Industry Communication::L Law
    Language: Spanish
    Format: image/jpeg
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  • 6
  • 7
    Publication Date: 2021-09-23
    Description: The underserved population could be at risk during the times of crisis, unless there is strong involvement from government agencies such as local and state Health departments and federal Center for Disease Control (CDC). The COVID-19 pandemic was a crisis of different proportion, creating a different type of burden on government agencies. Vulnerable communities including the elderly populations and communities of color have been especially hard hit by this pandemic. This forced these agencies to change their strategies and supply chains to support all populations receiving therapeutics. The National Science Foundation [National Science Foundation (NSF) Award Abstract # 2028612] funded RAID Labs to help federal agencies with strategies. This paper is based on a NSF funded grant to work on investigating supply chain strategies that would minimize the impact on underserved populations during pandemic. This NSF funded study identified the phenomena of last mile importance. The last mile transportation concept was critical in saving lives during the pandemic for underserved populations. The supply chain model then maximizes social goods by sending drugs or vaccines to the communities that need it the most regardless of ability to pay. The outcome of this study helped us prioritize the communities that need the vaccines the most. This informs our supply chain model to shift resources to these areas showing the value in real time prioritization of the COVID-19 supply chain. This paper provides information can be used in our healthcare supply chain model to ensure timely delivery of vaccines and supplies to COVID-19 patients that are the most vulnerable and hence the overall impact of COVID-19 can be minimized. The use of electrical vehicles for last mile transportation can help in significantly fighting the climate change.
    Electronic ISSN: 2673-5210
    Topics: Architecture, Civil Engineering, Surveying
    Published by Frontiers Media
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  • 8
    Publication Date: 2022-10-21
    Description: B.A.P. "Carrasco": Nuevas capacidades de investigación científica hidro-oceanográfica - A bordo del B.A.P. "Zimic": sembrando de boyas ARGO para el monitoreo regional del fenómeno "El Niño" - Así como en los estudios de "El NIño": Importancia de las boyas ARGO en el monitoreo de las condiciones oceanográficas - Boletín diario de las condiciones oceanográficas al alcance de todos - Carta Náutica HIDRONAV-112 "Punta Sal a Punta Pariñas": Primer cruceso hidro-geológico con INGEMMET - Centro Nacional de Alerta de Tsunamis: Alerta temprana para salvar vidas - Implementación operacional del modelo atmosférico en la DHN - Microprograma televisivo "Alerta El Niño" - Levantamiento hidrográfico en el Lago Titicaca - Evolución tecnológica para levantamientos hidrográficos - Actualización de cartas náuticas electrónicas - Cartas náuticas de papel aplicando el CARIS Paper Chart Composer - Evolución histórica de las ayudas a la navegación marítima - Eficaz sistema de supervisión remota y control para faros - Exitoso lanzamiento: Primer satélite peruano de observación de la tierra PerúSat - 1 - Uso de drones para la actualización cartográfica - Geotecnología en la gestión de crisis - NAVAREA: importante servicio de apoyo a los navegantes en general - Actualización de cartas y publicación náuticas - Formando a los futuros hidrógrafos - Inspección de la frontera peruano - colombiana: Avances del grupo técnico binacional
    Description: Published
    Description: Refereed
    Keywords: Cartas náuticas ; Fenómeno El Niño ; Levantamiento hidrográfico ; ASFA_2015::O::Oceanography ; ASFA_2015::H::Hydrography ; ASFA_2015::C::Climatic changes
    Repository Name: AquaDocs
    Type: Book/Monograph/Conference Proceedings
    Format: 96pp.
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  • 9
    Publication Date: 2024-03-22
    Description: This dataset contains the results of the fluorescent dissolved organic matter characterisation (FDOM) and water mass optimum multiparameter analysis from the MAFIA cruise (Migrants and Active Flux In the Atlantic ocean). Samples were collected in the tropical and subtropical Atlantic during the MAFIA cruise (April 2015) on board the BIO Hespérides. Seawater samples for biogeochemical analyses were collected at 13 stations (from the Brazilian coast to the Canary Islands), from the surface down to 3500 m, using a General Oceanics oceanographic rosette equipped with 24 l PVC Niskin bottles. Oxygen solubility was computed using the equation of Benson and Krause (1984). AOU (µmol/kg) was calculated by subtracting measured oxygen concentration from the oxygen solubility values at saturation, with respect to the atmosphere. Fluorescence measurements were performed with a Perkin-Elmer LS55 spectrofluorometer and FDOM was characterised by means of a Parallel Factor analysis. Integrated values were estimated by multiplying the discrete measurements by the distance, in meters, between samples. The contribution of each water mass to each sample was objectively quantified applying an optimum multiparameter analysis (excluding mixed layer samples, here 〈 100 m). The aim of this dataset was to jointly characterise the FDOM and water mass distributions to infer the processes that shape the dissolved organic matter pool in the deep ocean (water mass mixing and history vs. local processes).
    Keywords: Absorption coefficient, colored dissolved organic matter at 254 nm; Antarctic Intermediate Water of 3.1°C, relative volume contribution; Antarctic Intermediate Water of 5°C, relative volume contribution; Atlantic; Atlantic Ocean; bathypelagic; Biogeochemical impact of mesoscale and sub-mesoscale processes along the life history of cyclonic and anticyclonic eddies: plankton variability and productivity; Calculated; Calculated after Broecker (1974); Campaign; Chlorophyll a, integrated; Circumpolar Deep Water, relative volume contribution; Constraining organic carbon fluxes in an eastern boundary upwelling ecosystem (NW Africa): the role of non-sinking carbon in the context of the biological pump; Continuous Segmented Flow Analyzer, SEAL Analytical, QuAAtro39; CTD, Sea-Bird, SBE 911plus; CTD/Rosette; CTD-RO; dark ocean; Date/Time of event; DEPTH, water; Eastern North Atlantic Central Water of 12°C, relative volume contribution; Eastern North Atlantic Central Water of 15°C, relative volume contribution; e-IMPACT; Equatorial Water, relative volume contribution; Event label; Fluorescence intensity, maximum, DOM; fluorescent dissolved organic matter; FLUXES; Hespérides; Latitude of event; Longitude of event; Madeira Mode Water, relative volume contribution; MAFIA; MAFIA_01_D-1; MAFIA_02_L-1; MAFIA_03_L-1; MAFIA_04_L-1; MAFIA_05_L-1; MAFIA_06_L-1; MAFIA_07_L-1; MAFIA_08_L-1; MAFIA_09_L-1; MAFIA_10_D-1; MAFIA_11_L-1; MAFIA_12_L-1; MAFIA_13-1; Mediterranean Water, relative volume contribution; mesopelagic; Migrants and Active Flux In the Atlantic Ocean; Nitrate + Oxygen tracer; North Atlantic Deep Water of 2°C, relative volume contribution; North Atlantic Deep Water of 4.6°C, relative volume contribution; optimum multiparameter analysis; Optimum multiparameter analysis; Oxygen; Oxygen, apparent utilization; Oxygen, Benson & Krause 1984; Parallel factor analysis (PARAFAC); Pressure, water; Salinity; Salinity Maximum Water, relative volume contribution; Sample ID; Silicate; Spectrophotometer, Ocean Optics USB2000; Station label; Subpolar Mode Water, relative volume contribution; subtropical - tropical Atlantic; SUMMER; Sustainable Management of Mesopelagic Resources; Temperature, water, potential; Titration, Winkler; water masses
    Type: Dataset
    Format: text/tab-separated-values, 6717 data points
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  • 10
    Publication Date: 2024-03-22
    Description: This dataset contains the results of the fluorescent dissolved organic matter characterisation (FDOM) and water mass optimum multiparameter analysis from the MAFIA cruise (Migrants and Active Flux In the Atlantic ocean). Samples were collected in the tropical and subtropical Atlantic during the MAFIA cruise (April 2015) on board the BIO Hespérides. Seawater samples for biogeochemical analyses were collected at 13 stations (from the Brazilian coast to the Canary Islands), from the surface down to 3500 m, using a General Oceanics oceanographic rosette equipped with 24 l PVC Niskin bottles. Oxygen solubility was computed using the equation of Benson and Krause (1984). AOU (µmol/kg) was calculated by subtracting measured oxygen concentration from the oxygen solubility values at saturation, with respect to the atmosphere. Fluorescence measurements were performed with a Perkin-Elmer LS55 spectrofluorometer and FDOM was characterised by means of a Parallel Factor analysis. The flag denotes if FDOM values were from direct measurement or are interpolated values (some interpolated values were added to match the 16S amplicon data). Integrated values were estimated by multiplying the discrete measurements by the distance, in meters, between samples.The aim of this dataset was to jointly characterise the FDOM and water mass distributions to infer the processes that shape the dissolved organic matter pool in the deep ocean (water mass mixing and history vs. local processes).
    Keywords: Absorption coefficient, colored dissolved organic matter at 254 nm; Atlantic; Atlantic Ocean; bathypelagic; Biogeochemical impact of mesoscale and sub-mesoscale processes along the life history of cyclonic and anticyclonic eddies: plankton variability and productivity; Calculated; Campaign; Chlorophyll a, integrated; Constraining organic carbon fluxes in an eastern boundary upwelling ecosystem (NW Africa): the role of non-sinking carbon in the context of the biological pump; CTD, Sea-Bird, SBE 911plus; CTD/Rosette; CTD-RO; dark ocean; Date/Time of event; DEPTH, water; e-IMPACT; Event label; Fluorescence intensity, maximum, DOM; fluorescent dissolved organic matter; FLUXES; Hespérides; Latitude of event; Longitude of event; MAFIA; MAFIA_01_D-1; MAFIA_02_L-1; MAFIA_03_L-1; MAFIA_04_L-1; MAFIA_05_L-1; MAFIA_06_L-1; MAFIA_07_L-1; MAFIA_08_L-1; MAFIA_09_L-1; MAFIA_10_D-1; MAFIA_11_L-1; MAFIA_12_L-1; mesopelagic; Migrants and Active Flux In the Atlantic Ocean; optimum multiparameter analysis; Oxygen; Oxygen, apparent utilization; Oxygen, Benson & Krause 1984; Parallel factor analysis (PARAFAC); Pressure, water; Salinity; Sample ID; Spectrophotometer, Ocean Optics USB2000; Station label; SUMMER; Sustainable Management of Mesopelagic Resources; Temperature, water, potential; Titration, Winkler; Validation flag/comment; water masses
    Type: Dataset
    Format: text/tab-separated-values, 3925 data points
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