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  • 1
    Online Resource
    Online Resource
    Ethology and Behavioral Ecology of Phocids (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Freshwater ecology. ; Marine ecology. ; Conservation biology. ; Ecology . ; Biodiversity. ; Zoology. ; Behavior genetics. ; Freshwater and Marine Ecology. ; Conservation Biology. ; Ecology. ; Biodiversity. ; Zoology. ; Behavioral Genetics.
    Description / Table of Contents: Evolution – Analisa Berta -- Sensory and cognition – Tentative Colleen Reichmuth and others -- Communication – Isabelle Charrier -- Physiology – Dan Crocker -- Movement – Luis Huckstadt and Ryan Reisinger -- Navigation – Patrick Robinson -- Foraging ecology and behavior – Don Bowen -- Reproductive behavior and lactation strategies – Dan Costa and Jen Maresh -- Breeding behavior – Paddy Pomeroy and Kelly Robinson -- Conservation – Samantha Simmons and others.
    Abstract: Phocid (or earless or true) seals are ecologically diverse, occupying habitats from the tropics to the poles in marine and freshwater and feeding on anything from tiny zooplankton to other marine mammals. There are 18 species of phocid seals, the smallest species (ringed seal) is more than 20 times smaller than the largest (southern elephant seal), with marked sexual dimorphism present in some species. This book examines the behavior, ecology, and physiology that allow phocid seals to inhabit such a wide range of habitats. The book is composed of 16 chapters written by 37 authors from 8 countries. The book first describes the general patterns of phocid behavior, followed by descriptions of what is known about well-studied species. We have taken a holistic approach, focusing not only on the behaviors themselves but also on the factors that constrain the expression of behavior and the proximate mechanisms driving behavior. In many cases, the chapters represent collaborations between well-established researchers and early-mid career individuals who bring new perspectives to help carry the field of phocid behavioral ecology well into the future.
    Type of Medium: Online Resource
    Pages: XVIII, 645 p. 180 illus., 161 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030889234
    Series Statement: Ethology and Behavioral Ecology of Marine Mammals,
    URL: https://doi.org/10.1007/978-3-030-88923-4
    DOI: 10.1007/978-3-030-88923-4
    DDC: 577.6
    Language: English
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  • 2
    Online Resource
    Online Resource
    Mangroves: Biodiversity, Livelihoods and Conservation (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Forestry. ; Zoology. ; Botany. ; Forestry. ; Zoology. ; Plant Science.
    Description / Table of Contents: Chapter 1. Mangroves- A Unique Ecosystem and its Significance -- Chapter 2. Mangrove Forests and Silviculture -- Chapter 3. A Review of the Reproductive Ecology of Mangrove Plant Species -- Chapter 4. Mangrove Health Analysis using Multi-temporal Sentinel-2 Multi-Spectral Instrument (MSI) Data -- Chapter 5. Ethnobotany of Mangroves - A Review -- Chapter 6. Mangrove Ecosystems and their Services -- Chapter 7. Mangrove Forests and People’s Livelihoods -- Chapter 8. Climate Change and Mangroves -- Chapter 9. Rehabilitation and Restoration of Mangroves -- Chapter 10. Threats to Mangroves and conservation strategies -- Chapter 11. Mangrove Forests of India: An Overview -- Chapter 12. Mangroves of Sundarban -- Chapter 13 -- Sri Lankan Mangroves: Biodiversity, livelihoods and conservation -- Chapter 14. Mangroves in Myanmar -- Chapter 15. Mangroves of Malaysia -- Chapter 16. Mangrove Biodiversity, Conservation, and Roles for Livelihoods in Indonesia -- Chapter 17. Mangroves Sustaining Biodiversity, Local Livelihoods, Blue Carbon and Local Resilience in Verde Island Passage in Luzon, Philippines -- Chapter 18. Mangroves of Japan -- Chapter 19. Mangroves of Ecuador -- Chapter 20. Mangroves of Brazil -- Chapter 21. Cameroon mangroves: current status uses challenges and management perspectives.
    Abstract: This contributory volume is a comprehensive collection on the mangrove forest eco-system and its ecology, the resources and potentials of mangroves, conservation efforts, mangrove eco-system services and threats to conservation. The book is an all-inclusive compilation on the status, conservation and future of mangroves. Mangroves are a unique ecosystem providing several ecosystem services. They are formed in the inter-tidal areas of large rivers and coastal islands. Mangroves thrives due to constant interaction with the terrestrial and marine ecosystem. These are the species dynamics, varying tidal amplitudes, plant succession, changing floral pattern of the channels of the estuary, the varying sediment transportation. There was 20% decline in mangrove forest area in the last 25 years due mainly to conversion and coastal development. Lengthy recovery periods required for the degraded mangrove forests. Hence there is an urgent need to take stock of the updated information on these mangroves at global level. It is of immense value to scientific community involved in teaching, research and extension activities related to mangrove conservation.
    Type of Medium: Online Resource
    Pages: VIII, 609 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811905193
    URL: https://doi.org/10.1007/978-981-19-0519-3
    DOI: 10.1007/978-981-19-0519-3
    DDC: 634.9
    Language: English
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  • 3
    Online Resource
    Online Resource
    Drug Delivery to the Brain : Physiological Concepts, Methodologies and Approaches (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Drug delivery systems. ; Neuropharmacology. ; Medicine Research. ; Biology Research. ; Pharmaceutical chemistry. ; Drug Delivery. ; Neuropharmacology. ; Biomedical Research. ; Pharmaceutics.
    Description / Table of Contents: Part I-Physiology and Basic Principles of Drug Handling for the CNS -- Anatomy and Physiology of the Blood Brain Barriers -- Drug Delivery to the Brain: Integrating Neuroscience, Physiology, and Brain Barriers Science -- Brain Delivery of Therapeutics via Transcytosis: Types and Mechanisms of Vesicle-Mediated Transport Across the BBB -- Brain- Arachnoid Barrier as an Important Clearance Pathway from CSF -- BBB Pharmacoproteomics: Quantitative Targeted Absolute Proteomics (QTAP): Species Differences -- Drug Metabolism at the BBB and the BCFSB -- PART II-PK Concepts and Methods for Studying CNS Drug Delivery -- Pharmacokinetics Concepts in Brain Drug Delivery -- In Vitro Models of CNS Barriers -- Human In Vitro BBB Models Derived from Pluripotent Stem Cells -- In situ and In vivo Animal Models -- Principles of PET and Its Role in Understanding Drug Delivery to the Brain -- Prediction of CNS PK and PD Using Translational Research Approaches -- Part III-Industrial Approaches for Investigation of Potential CNS Drugs -- Drug Discovery Methods for Studying Brain Drug Delivery and Distribution -- Prediction of Drug Exposure in the Brain From the Chemical Structure -- Integrated Approach to Optimizing CNS Penetration in Drug Discovery -- Part IV: Strategies for Improved CNS Drug Delivery -- Intranasal Drug Delivery to the Brain -- Blood to Brain Drug Delivery Using Nanocarriers -- Enhancing CNS Exposure Through Brain Endothelial Cell RMT-Exploiting the Transferrin Receptor at the BBB -- Therapeutic Osmotic Modification of the BBB in the Treatment of CNS Pathologies -- Biophysical Perspectives on BBB Permeability Enhancement by Ultrasound and Microbubbles for Targeted Drug Delivery in the Clinical Setting -- Optimization of Blood Brain Barrier Opening With Focused Ultrasound-The Animal Perspective -- CNS Gene Therapy Using Adeno-Associated Virus (AAV) Vectors -- Part V-CNS Drug Delivery in Disease Conditions -- Disease Influence on BBB Transport in Neurodegeneration and Neuroinflammation -- Enhancing Drug Delivery in the Setting of Stroke and Brain Injury -- Drug Delivery to tumor Metastases in the Brain-(Including PK PD Free Fraction Active Conc.) -- Drug Delivery to Primary Tumors in the Brain-(Including PK PD Free Fraction Active Conc.) -- Appendix:CNS Anatomy, Function, Vasculature and Fluid Exchange: Primer for Drug Delivery Scientists.
    Abstract: The development of new CNS drugs is notoriously difficult. Drugs must reach CNS target sites for action and these sites are protected by a number of barriers, the most important being the blood–brain barrier (BBB). Many factors are therefore critical to consider for CNS drug delivery, e.g. active/passive transport across the BBB, intra-brain distribution, and central/systemic pharmacokinetics, to name a few. Neurological disease and trauma conditions add further complexity because CNS barriers, drug distribution and pharmacokinetics are dynamic and often changed by disease/trauma. Knowledge of all these factors and their interplay in different conditions is of utmost importance for proper CNS drug development and disease treatment. In recent years much information has become available for a better understanding of the many factors important for CNS drug delivery and how they interact to affect drug action. This book describes small and large drug delivery to the brain with an emphasis on the physiology of the BBB and the principles and concepts for drug delivery across the BBB and distribution within the brain. It contains methods descriptions for studying drug delivery, routes and approaches of administering drugs into the brain, the influence of disease, drug industry perspectives, and a primer on neuroanatomy and physiological considerations written specifically for drug delivery scientists. Therewith, it contributes to an in-depth understanding of the interplay between brain (patho)-physiology and drug characteristics. Furthermore, the content is designed to be both cutting-edge and educational, so that the book can be used in high-level training of academic and industry scientists with full references to original publications. .
    Type of Medium: Online Resource
    Pages: XXI, 806 p. 199 illus., 179 illus. in color. , online resource.
    Edition: 2nd ed. 2022.
    ISBN: 9783030887735
    Series Statement: AAPS Advances in the Pharmaceutical Sciences Series, 33
    URL: https://doi.org/10.1007/978-3-030-88773-5
    DOI: 10.1007/978-3-030-88773-5
    DDC: 615.6
    Language: English
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  • 4
    Online Resource
    Online Resource
    Engineering Biomaterials for Neural Applications (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Biomedical engineering. ; Neurosciences. ; Biotechnology. ; Biomedical Research. ; Biomedical Engineering and Bioengineering. ; Biomedical Devices and Instrumentation. ; Neuroscience. ; Biotechnology.
    Description / Table of Contents: Chapter 1. Scaffolds for promoting neural repair -- Chapter 2. Composites for nerve regeneration -- Chapter 3. Configurable models of the blood-brain barrier -- Chapter 4. Engineering nerve conduits -- Chapter 5. Flexible electronics for stem cell differentiation -- Chapter 6. Nanosensors for brain chemistry -- Chapter 7. Nanomaterials for imaging the brain ECS -- Chapter 8. Microfluidics for analysis of neuronal development -- Chapter 9. Multiple particle tracking measurements of extracellular matrix dysregulation -- Chapter 10. Bioresponsive nanomaterials for treatment of CNS disease -- Chapter 11. Redox regulation for controlling cell fate -- Chapter 12. Polymersome delivery of CRISPR-based therapies -- Chapter 13. Multifunctional polymers for targeted delivery -- Chapter 14. Theranostic nanomaterials for brain injury.
    Abstract: This contributed volume explores the ways in which researchers engineer new biomaterials for the challenging problems of the peripheral and central nervous systems. These biomaterials are uniquely positioned for use in creating in vitro models of injury and disease, testing therapeutic treatments, understanding neural development, and mapping the multi-scalar environment of the brain. This book informs readers from biology, chemistry, materials science, engineering, and neuroscience on cutting edge research in engineering technologies, from fundamental material development through pre-clinical studies. The book also highlights target applications in three areas of research: (1) engineering neural models and materials, (2) probing biological underpinnings of neurological function and disease, and (3) designing therapeutic and diagnostic treatments for neurological disease. .
    Type of Medium: Online Resource
    Pages: VIII, 353 p. 64 illus., 61 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031114090
    URL: https://doi.org/10.1007/978-3-031-11409-0
    DOI: 10.1007/978-3-031-11409-0
    DDC: 610.72
    Language: English
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  • 5
    Online Resource
    Online Resource
    Biomarkers for Huntington's Disease : Improving Clinical Outcomes (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Neurosciences. ; Neurology . ; Neurophysiology. ; Neuropharmacology. ; Neuroscience. ; Neurology. ; Neurophysiology. ; Neuropharmacology.
    Description / Table of Contents: Molecular Biomarkers.Somatic instability/Telomeres,- Genetic modifiers -- Current clinical trial biomarkers.-Pharmacodynamic biomarkers for Htt-lowering therapeutics.-Inflammatory biomarkers.-Sleep dysregulation markers.-Mitochondrial/Oxidative stress biomarkers.-Microbiomics -- Metabolomics.-Proteomics.-Transcriptomics.-Lipidomics.-Imaging marker overview.-Retinal imaging biomarkers -- MRI - non-invasive functional MRI measures -- The evolution of clinical trial methodology.-Digital biomarkers -- The future of telehealth -- Summary and future trends.
    Abstract: Huntington’s disease (HD) is a fatal, inherited, neurodegenerative disorder, characterized by chorea, motor instabilities, psychiatric manifestations and cognitive decline. Early genetic testing provides an opportunity for clinical interventions aimed at delaying onset and/or slowing progression of disease; however, current treatments for HD are limited, with only two FDA-approved drugs available to manage chorea. Encouragingly, however, several disease-modifying treatment approaches are in the therapeutic pipeline, with more than 200 clinical studies, and many more preclinical studies, in the works. Robust and reliable biomarkers are needed to predict disease onset, monitor disease progression and assess treatment responses. More specifically, biomarkers to stratify patients for clinical trials and biomarkers to track drug efficacy will certainly lead to improved clinical trial design and success. This book represents the first book focused solely on biomarkers for HD and represents a distinct resource that will be informative, not only for clinicians and those involved in clinical trial design, but also for a wide range of neurodegenerative disease researchers. This edited volume is written by top leaders in the field, and takes a cross-disciplinary approach to cover a broad spectrum of biomarker types, in order to provide the latest advances in the development of biochemical, molecular, imaging and digital biomarkers that have been investigated for HD. With the ultimate goal of treating patients, the development of disease-associated biomarkers has never been more important.
    Type of Medium: Online Resource
    Pages: XVI, 475 p. 42 illus., 39 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031328152
    Series Statement: Contemporary Clinical Neuroscience,
    URL: https://doi.org/10.1007/978-3-031-32815-2
    DOI: 10.1007/978-3-031-32815-2
    DDC: 612.8
    Language: English
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  • 6
    Online Resource
    Online Resource
    Pandemic Cities : The COVID-19 Crisis and Australian Urban Regions (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Sustainability. ; Urban policy. ; Public health. ; Urban economics. ; Human geography. ; Sustainability. ; Urban Policy. ; Public Health. ; Urban Economics. ; Human Geography.
    Description / Table of Contents: COVID-19 and Australian cities: when the pandemic came to town -- Population challenges and change in pandemic cities -- COVID-19 and the social structure of cities: The forgotten vulnerable -- The great job reshuffle: How COVID-19 changed urban labour markets -- Housing and the pandemic -- Moving around the COVID city -- Planning the COVID city -- The future of COVID cities.
    Abstract: This book highlights the impact of the COVID-19 pandemic on cities. The COVID-19 pandemic and the associated economic and social impacts have been felt around the world. In large cities and other urban areas, the pandemic has highlighted a number of issues from pressures on urban labour and housing markets, shifts in demographic processes including migration and mobility, changes in urban travel patterns and pressures on contemporary planning and governance processes. Despite Australia’s relatively mild COVID exposure, Australian cities and large urban areas have not been immune to these issues. The economic shutdown of the country in the early stages of the pandemic, the sporadic border closures between states, the effective closure of international borders and the imposition of widespread public health orders that have required significant behavioural change across the population have all changed our cities in some and the way we live and work in them in some way. Some of the challenges have reflected long-standing problems including intrenched inequality in labour markets and housing markets, others such as the impact on commuting patterns and patterns of migration have emerged largely during the pandemic. This book, co-authored by experts in their field, outlines some of the major issues facing Australian cities and urban areas as a result of the pandemic and sets a course for future of the cities we live in.
    Type of Medium: Online Resource
    Pages: XII, 123 p. 49 illus., 47 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811958847
    Series Statement: Cities Research Series,
    URL: https://doi.org/10.1007/978-981-19-5884-7
    DOI: 10.1007/978-981-19-5884-7
    DDC: 304.2
    Language: English
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  • 7
    Monograph available for loan
    Monograph available for loan
    Chemical biomarkers in aquatic ecosystems (2011)
    Princeton, N.J. [u.a.] : Princeton Univ. Press
    Details Availability
    Call number: 10/M 12.0302
    Description / Table of Contents: Contents: Chapter 1. Metabolic Synthesis Chapter 2. Chemical Biomarker Applications to Ecology and Paleoecology Chapter 3. Stable Isotopes and Radiocarbon Chapter 4. Analytical Chemical Methods and Instrumentation Chapter 5. Carbohydrates: Neutral and Minor Sugars Chapter 6. Proteins: Amino Acids and Amines Chapter 7. Nucleic Acids and Molecular Tools Chapter 8. Lipids: Fatty Acids Chapter 9. Isoprenoid Lipids: Steroids, Hopanoids, and Triterpenoids Chapter 10. Lipids: Hydrocarbons Chapter 11. Lipids: Alkenones, Polar Lipids, and Ether Lipids Chapter 12. Photosynthetic Pigments: Chlorophylls, Carotenoids, and Phycobilins Chapter 13. Lignins, Cutins, and Suberins Chapter 14. Anthropogenic Markers Appendix I. Atomic Weights of Elements Appendix II. Useful SI Units and Conversion Factors Appendix III. Physical and Chemical Constants Glossary Bibliography
    Type of Medium: Monograph available for loan
    Pages: xvii, 396 S. , Ill., graph. Darst. , 26 cm
    ISBN: 9780691134147
    Classification:
    Geochemistry
    Location: Reading room
    Branch Library: GFZ Library
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  • 8
    Monograph available for loan
    Monograph available for loan
    Debating climate change : pathways through argument to agreement (2009)
    London [u.a.] : Earthscan
    Details Availability
    Call number: PIK N 071-09-0303
    Description / Table of Contents: Contents: Preface: Climate Change in the Spotlight ; 1. Introduction: Trying to Make Sense of Disparate Arguments about Climate Change ; 2. The Many Faces of Dispute ; 3. Climate Change - Part of Globalization? ; 4. Arguments - Agreeing and Disagreeing ; 5. Finding Common Ground: The Features of the Arguments Themselves ; 6. Elements of Arguments as Social Links ; 7. Beyond Family Ties: Social Network Analysis ; 8. Prospects for the Debate: Endless Recycling of Arguments or Movement toward Agreement? ; Appendix 1 Arguments sorted by family with coded rhetorical features ; Appendix 2. Documents listed by argument
    Type of Medium: Monograph available for loan
    Pages: XV, 143 S. : graph. Darst.
    ISBN: 9781844078295
    Location: A 18 - must be ordered
    Branch Library: PIK Library
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  • 9
    Monograph available for loan
    Monograph available for loan
    The Contextual Determinants of Malaria (2002)
    Washington D.C. : Resources for the Future
    Details Availability
    Call number: PIK O 080-03-0170
    Type of Medium: Monograph available for loan
    Pages: XV, 382 p.
    ISBN: 1891853198
    Location: A 18 - must be ordered
    Branch Library: PIK Library
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  • 10
    Monograph available for loan
    Monograph available for loan
    Atmospheres : a view of the gaseous envelopes surrounding members in our solar system (1981)
    New York [u.a.] : Pergamon Press
    Details Availability
    Call number: AWI A16-96-0033
    Type of Medium: Monograph available for loan
    Pages: XIX, 266 S.
    ISBN: 0080255825
    Series Statement: Pergamon international library of science, technology, engineering and social studies
    Branch Library: AWI Library
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