ISSN:
1420-9071
Keywords:
Na, K, Mg ATPase
;
ouabain
;
negative cooperativity
;
multi-site ouabain binding
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary The inhibition of sarcolemmal Na, K, Mg ATPase from the guinea pig heart by ouabain was evaluated with a coupled enzyme assay. Models of negative cooperativity and of two independent receptors fitted the inhibition data equally well. The analysis was not compatible with a homogeneous population of non-interacting ouabain receptors.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01951701
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