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  • 1
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    Evidence for hormonal control of heart regenerative capacity during endothermy acquisition (2019)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2019
    Description: 〈p〉Tissue regenerative potential displays striking divergence across phylogeny and ontogeny, but the underlying mechanisms remain enigmatic. Loss of mammalian cardiac regenerative potential correlates with cardiomyocyte cell-cycle arrest and polyploidization, as well as the development of postnatal endothermy. We reveal that diploid cardiomyocyte abundance across 41 species conforms to Kleiber’s law–the 3/4-power law scaling of metabolism with bodyweight–and inversely correlates with standard metabolic rate, body temperature, and serum thyroxine level. Inactivation of thyroid hormone signaling reduces mouse cardiomyocyte polyploidization, delays cell-cycle exit, and retains cardiac regenerative potential in adults. Conversely, exogenous thyroid hormones inhibit zebrafish heart regeneration. Thus, our findings suggest that loss of heart regenerative capacity in adult mammals is triggered by increasing thyroid hormones and may be a tradeoff for the acquisition of endothermy.〈/p〉
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Natural Sciences in General
    Published by American Association for the Advancement of Science (AAAS)
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  • 2
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    Trophic positioning of meiofauna revealed by stable isotopes and food-web analyses (2016)
    Wiley
    In: Ecology
    Details
    Publication Date: 2016-08-07
    Description: Despite important advances in the ecology of river food-webs, the strength and nature of the connection between the meio- and macrofaunal components of the web are still debated. Some unresolved issues are the effects of the inclusion of meiofaunal links and their temporal variations on the overall river food web properties, and the significance of autochtonous and allochtonous material for these components. In the present study we conducted gut content of macro- and meiofauna, and stable isotope analyses of meiofauna to examine seasonal food webs of a chalk stream. The results of the gut content analyses, confirmed by the δ 13 C signatures, revealed a seasonal shift from a dependence on autochthonous (biofilm) to allochthonous food sources. Here, we demonstrate that aggregating basal or meiofaunal species into single categories affects key web properties such as web size, links, linkage density, and predator-prey ratios. More importantly, seasonal variation in attributes characterized the entire web and these changes persist regardless of taxonomic resolution. Furthermore, our analyses evidenced discrete variations in δ 15 N across the meiofauna community with a trophic structure that confirms gut content analyses, placing the meiofauna high in the food web. We, therefore, conclude that small body-sized taxa can occur high in dynamic river food webs, questioning assumptions that trophic position increases with body size and that webs are static. This article is protected by copyright. All rights reserved.
    Print ISSN: 0012-9658
    Electronic ISSN: 1939-9170
    Topics: Biology
    Published by Wiley on behalf of The Ecological Society of America (ESA).
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  • 3
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    Farm household risk balancing: empirical evidence from Switzerland (2016)
    Oxford University Press
    Details
    Publication Date: 2016-08-09
    Description: Empirical evidence on household risk balancing behaviour is presented by estimating a fixed effects seemingly unrelated regression model using Swiss Farm Accountancy Data Network data. We find that in response to changes in expected business risks, Swiss farm households not only make strategic farm financial risk decisions (original risk balancing), but also make strategic off-farm decisions (household risk balancing) by altering their share of off-farm income and relative consumption. Small farms appear to make more use of household risk balancing strategies whereas large farms conversely make more use of the original risk balancing strategy.
    Print ISSN: 0165-1587
    Electronic ISSN: 1464-3618
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Economics
    Published by Oxford University Press
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  • 4
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    Dual role of CO in Pt cluster stability [Chemistry] (2016)
    National Academy of Sciences
    Details
    Publication Date: 2016-08-11
    Description: Interactions between catalytically active metal particles and reactant gases depend strongly on the particle size, particularly in the subnanometer regime where the addition of just one atom can induce substantial changes in stability, morphology, and reactivity. Here, time-lapse scanning tunneling microscopy (STM) and density functional theory (DFT)-based calculations are used...
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
    Published by National Academy of Sciences
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  • 5
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    Greenhouse-gas payback times for crop-based biofuels (2015)
    Springer Nature
    Details
    Publication Date: 2015-05-22
    Description: Greenhouse-gas payback times are derived for biofuel production systems using five feedstocks under high- and low-input farm management to assess replacement of natural vegetation with crop-based biofuels. Estimates ranged from 1–162 years. Nature Climate Change 5 604 doi: 10.1038/nclimate2642
    Print ISSN: 1758-678X
    Electronic ISSN: 1758-6798
    Topics: Geosciences
    Published by Springer Nature
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  • 6
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    Climate change induced transformations of agricultural systems: insights from a global model (2014)
    Institute of Physics (IOP)
    Details
    Publication Date: 2014-12-19
    Description: Climate change might impact crop yields considerably and anticipated transformations of agricultural systems are needed in the coming decades to sustain affordable food provision. However, decision-making on transformational shifts in agricultural systems is plagued by uncertainties concerning the nature and geography of climate change, its impacts, and adequate responses. Locking agricultural systems into inadequate transformations costly to adjust is a significant risk and this acts as an incentive to delay action. It is crucial to gain insight into how much transformation is required from agricultural systems, how robust such strategies are, and how we can defuse the associated challenge for decision-making. While implementing a definition related to large changes in resource use into a global impact assessment modelling framework, we find transformational adaptations to be required of agricultural systems in most regions by 2050s in order to cope with climate change. However,...
    Print ISSN: 1748-9318
    Electronic ISSN: 1748-9326
    Topics: Biology , Energy, Environment Protection, Nuclear Power Engineering
    Published by Institute of Physics (IOP)
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  • 7
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    High resolution climate data for Austria in the period 2008–2040 from a statistical climate change model (2012)
    Wiley
    Details
    Publication Date: 2012-02-22
    Description: Climate change data for Austria have been produced for the period from 2008 to 2040, with a temporal/spatial resolution of 1 d and 1 km 2 . The climate change data are based on historical daily weather station data from 1975 to 2007, and linear regression modelling with repeated bootstrapping. The spatial resolution is based on 60 climate clusters which represent homogenous climates with respect to mean annual precipitation sums and mean annual temperatures from the period 1961 to 1990. For each climate cluster, a regression model fit has been performed and extrapolated for the period 2008–2040. The integral parts of our regression model are: (1) the extrapolation of the observed linear temperature trend from 1975 to 2007, by using an average national trend of approximately 0.05 °C per year derived from a homogenized dataset, and (2) the repeated bootstrapping of historical temperature residuals, and of the observations for some other weather parameters, such as solar radiation, precipitation, relative humidity and wind speed. Thus, we ensure consistent physical, spatial and temporal correlations. Precipitation scenarios have been developed to account for any possible wider range of precipitation patterns. These scenarios include increased/decreased annual precipitation sums, as well as unchanged annual precipitation sums, but with different seasonal distributions. These climate change data are available at: http://www.landnutzung.at/Klima_Daten.html Copyright © 2012 Royal Meteorological Society
    Print ISSN: 0899-8418
    Electronic ISSN: 1097-0088
    Topics: Geosciences , Physics
    Published by Wiley
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  • 8
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    High resolution climate data for Austria in the period 2008–2040 from a statistical climate change model (2012)
    Wiley
    Details
    Publication Date: 2012-04-15
    Description: Climate change data for Austria have been produced for the period from 2008 to 2040, with a temporal/spatial resolution of 1 d and 1 km 2 . The climate change data are based on historical daily weather station data from 1975 to 2007, and linear regression modelling with repeated bootstrapping. The spatial resolution is based on 60 climate clusters which represent homogenous climates with respect to mean annual precipitation sums and mean annual temperatures from the period 1961 to 1990. For each climate cluster, a regression model fit has been performed and extrapolated for the period 2008–2040. The integral parts of our regression model are: (1) the extrapolation of the observed linear temperature trend from 1975 to 2007, by using an average national trend of approximately 0.05 °C per year derived from a homogenized dataset, and (2) the repeated bootstrapping of historical temperature residuals, and of the observations for some other weather parameters, such as solar radiation, precipitation, relative humidity and wind speed. Thus, we ensure consistent physical, spatial and temporal correlations. Precipitation scenarios have been developed to account for any possible wider range of precipitation patterns. These scenarios include increased/decreased annual precipitation sums, as well as unchanged annual precipitation sums, but with different seasonal distributions. These climate change data are available at: http://www.landnutzung.at/Klima_Daten.html Copyright © 2012 Royal Meteorological Society
    Print ISSN: 0899-8418
    Electronic ISSN: 1097-0088
    Topics: Geosciences , Physics
    Published by Wiley
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  • 9
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    Copper-catalyzed asymmetric conjugate addition of organometallic reagents to extended Michael acceptors (2015)
    Beilstein-Institut
    Details
    Publication Date: 2015-12-05
    Description: The copper-catalyzed asymmetric conjugate addition (ACA) of nucleophiles onto polyenic Michael acceptors represents an attractive and powerful methodology for the synthesis of relevant chiral molecules, as it enables in a straightforward manner the sequential generation of two or more stereogenic centers. In the last decade, various chiral copper-based catalysts were evaluated in combination with different nucleophiles and Michael acceptors, and have unambiguously demonstrated their usefulness in the control of the regio- and enantioselectivity of the addition. The aim of this review is to report recent breakthroughs achieved in this challenging field. Beilstein J. Org. Chem. 2015, 11, 2418–2434. doi:10.3762/bjoc.11.263
    Keywords: conjugate additionselectron-deficient alkenesenantioselective catalysisextended Michael acceptorsorganometallic nucleophilessequential addition
    Electronic ISSN: 1860-5397
    Topics: Chemistry and Pharmacology
    Published by Beilstein-Institut
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  • 10
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    Relation between population density and body size in stream communities (2000)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2000-09-01
    Description: The existence of a general relation between population density and body size in animal assemblages has been debated because of known biases and ambiguities in the published data and data handling. Using new comprehensive data sets from two geographically separated stream communities that encompass 448 and 260 invertebrate taxa with a wide range of body sizes, we show that an inverse proportionality between density and body size is a consistent feature in these communities. The scaling across taxa is not statistically different between the two systems, indicating a convergent pattern of communities. Variation in the regression slope among different taxonomic groups indicates that these communities are not governed universally by a single ecological or energetic rule.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Schmid, P E -- Tokeshi, M -- Schmid-Araya, J M -- New York, N.Y. -- Science. 2000 Sep 1;289(5484):1557-60.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉School of Biological Sciences, Queen Mary & Westfield College, University of London, London E1 4NS, UK. p.e.schmid@qmw.ac.uk〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10968792" target="_blank"〉PubMed〈/a〉
    Keywords: Analysis of Variance ; Animals ; Austria ; Body Constitution ; *Ecosystem ; Fresh Water ; Invertebrates/*anatomy & histology/*physiology ; Mathematics ; Population Density ; Regression Analysis ; Wales
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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