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  • 1
    Publication Date: 2015-11-05
    Description: In the framework of the second phase of the Coordinated Ocean-ice Reference Experiments (CORE-II), we present an analysis of the representation of the Antarctic Circumpolar Current (ACC) and Southern Ocean meridional overturning circulation (MOC) in a suite of seventeen global ocean–sea ice models. We focus on the mean, variability and trends of both the ACC and MOC over the 1958–2007 period, and discuss their relationship with the surface forcing. We aim to quantify the degree of eddy saturation and eddy compensation in the models participating in CORE-II, and compare our results with available observations, previous fine-resolution numerical studies and theoretical constraints. Most models show weak ACC transport sensitivity to changes in forcing during the past five decades, and they can be considered to be in an eddy saturated regime. Larger contrasts arise when considering MOC trends, with a majority of models exhibiting significant strengthening of the MOC during the late 20th and early 21st century. Only a few models show a relatively small sensitivity to forcing changes, responding with an intensified eddy-induced circulation that provides some degree of eddy compensation, while still showing considerable decadal trends. Both ACC and MOC interannual variabilities are largely controlled by the Southern Annular Mode (SAM). Based on these results, models are clustered into two groups. Models with constant or two-dimensional (horizontal) specification of the eddy-induced advection coefficient κ show larger ocean interior decadal trends, larger ACC transport decadal trends and no eddy compensation in the MOC. Eddy-permitting models or models with a three-dimensional time varying κ show smaller changes in isopycnal slopes and associated ACC trends, and partial eddy compensation. As previously argued, a constant in time or space κ is responsible for a poor representation of mesoscale eddy effects and cannot properly simulate the sensitivity of the ACC and MOC to changing surface forcing. Evidence is given for a larger sensitivity of the MOC as compared to the ACC transport, even when approaching eddy saturation. Future process studies designed for disentangling the role of momentum and buoyancy forcing in driving the ACC and MOC are proposed.
    Repository Name: EPIC Alfred Wegener Institut
    Type: Article , isiRev
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  • 2
    Publication Date: 2015-11-05
    Description: We characterise the representation of the Southern Ocean water mass structure and sea ice within a suite of 15 global ocean-ice models run with the Coordinated Ocean-ice Reference Experiment Phase II (CORE-II) protocol. The main focus is the representation of the present (1988–2007) mode and intermediate waters, thus framing an analysis of winter and summer mixed layer depths; temperature, salinity, and potential vorticity structure; and temporal variability of sea ice distributions. We also consider the interannual variability over the same 20 year period. Comparisons are made between models as well as to observation-based analyses where available. The CORE-II models exhibit several biases relative to Southern Ocean observations, including an underestimation of the model mean mixed layer depths of mode and intermediate water masses in March (associated with greater ocean surface heat gain), and an overestimation in September (associated with greater high latitude ocean heat loss and a more northward winter sea-ice extent). In addition, the models have cold and fresh/warm and salty water column biases centred near 50°S. Over the 1988–2007 period, the CORE-II models consistently simulate spatially variable trends in sea-ice concentration, surface freshwater fluxes, mixed layer depths, and 200–700 m ocean heat content. In particular, sea-ice coverage around most of the Antarctic continental shelf is reduced, leading to a cooling and freshening of the near surface waters. The shoaling of the mixed layer is associated with increased surface buoyancy gain, except in the Pacific where sea ice is also influential. The models are in disagreement, despite the common CORE-II atmospheric state, in their spatial pattern of the 20-year trends in the mixed layer depth and sea-ice.
    Repository Name: EPIC Alfred Wegener Institut
    Type: Article , isiRev
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  • 3
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Vacuum 38 (1988), S. 839-842 
    ISSN: 0042-207X
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Chester : International Union of Crystallography (IUCr)
    Journal of synchrotron radiation 5 (1998), S. 783-785 
    ISSN: 1600-5775
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Geosciences , Physics
    Notes: Although a continuously tuneable source of photons is a very desirable feature of synchrotron radiation it has one main drawback: the contamination of the photon beam by higher-order diffracted light. Several elements have absorption edges which lie between 10 and 200 eV, a range prone to high second- and third-order content in XUV monochromators. They can, therefore, be used as transmission filters to reduce this higher-order content. This paper describes the use of thin filters to reduce the higher-order content in diffraction-grating monochromators. Their suppression efficiency, transmission and ageing have been characterized using photoelectron spectroscopy and compared with calculated values. The effect of oxide contamination on their performance has been assessed. Filters are now installed on eight XUV beamlines and have been in routine use for several years.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Chester : International Union of Crystallography (IUCr)
    Journal of synchrotron radiation 2 (1995), S. 264-271 
    ISSN: 1600-5775
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Geosciences , Physics
    Notes: Synchrotron-excited resonant-photoemission measurements at rare-earth 4d → 4f and transition-metal 3p → 3d thresholds have been carried out using a variety of complex cuprates and nickelates on stations 6.1 (grazing-incidence monochromator) and 6.2 (toroidal-grating monochromator) at the SRS CLRC Daresbury Laboratory. The systems studied are Nd2Ni1 − xCuxO4, La2 − xSrxNi1− yFeyO4 + δ and Bi2Sr2Ca1 − xYxCu2O8 + δ. A combination of EDC and constant-initial-state data is used to examine the 4f and 3d contributions to the valence-band density of states and their binding-energy positions relative to the Fermi energy. This allows the study of the valence states of the transition-metal ions and their modulation on doping. For La2 − xSrxNi1 − yFeyO4 + δ, this approach is used to infer a valence state of ≥ 3.0 for Fe. In the case of Bi2Sr2Ca1 − xYxCu2O8 + δ, the effect of Cu valence modulation on the 3p resonance is observed as x is varied. This is discussed in the light of controversy surrounding shifts in core-level photoemission with doping for this system.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Journal of materials science 2 (1991), S. 176-180 
    ISSN: 1573-4838
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Technology
    Notes: Abstract A ‘bioactive’ material, capable of active stimulation of osteogenesis, has been produced by adsorbing human growth hormone onto calcium phosphate ceramics. These materials can be used to deliver growth hormone at the bone-ceramic interface. The elution of the hormone occurs in two phases, with an initial rapid release followed by a slow continuous release for up to 25 days. Tricalcium phosphate was found to release growth hormone better than hydroxyapatite, probably due to the higher solubility of the ceramic.In vivo studies using a rabbit model were used to demonstrate osteointegration at the ceramic interface.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1573-4838
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Technology
    Notes: Abstract A qualitative in vitro evaluation of poly(caprolactone) (PCL), poly(hydroxybutyrate) (PHB) and a poly(hydroxybutyrate)-(hydroxyvalerate) (PHB-PHV) copolymer was carried out using primary human osteoblasts (HOB) and a human osteosarcoma (HOS) cell line. The cells were grown on films of these polymers and cultured for 2 and 4 days with cells grown on Thermanox as a control. The cells on each of the polymers exhibited different cellular morphologies with different rates of cell proliferation. Results from a preliminary degradation study demonstrated that biodegradable materials can be partially degraded using enzymes such as papain and trypsin. Of the solutions tested, papain caused the greatest degradation, with phosphate-buffered saline (PBS) a physiological buffer having very little effect over a six week period. The bone cells were grown on partially degraded polymers and no differences in the performance of HOS and HOB cells on the materials were observed.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1573-4838
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Technology
    Notes: Abstract The ultrastructural characteristics of the repair tissue in large articular cartilage defects, filled with a heterocyclic polymerizing system were studied using transmission electron microscopy (TEM) and energy dispersive micro-analysis (EDMA). By six weeks post-implantation, the defects were resurfaced with predominantly hyaline-like articular cartilage. Chondrocytes in both the superficial and deep zones of the repair tissue were highly productive, secreting large amounts of proteoglycans, into a well-organized, rich in collagen fibrils, extracellular matrix. By contrast, in the repair tissue of the defects treated without the biomaterial, proteoglycan synthesis was less and the structure of the matrix was inferior. We conclude that the polymer enhances both chondrocyte metabolism and matrix organization, thus improving the quality of the repair tissue in articular cartilage defects.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Journal of materials science 6 (1995), S. 590-596 
    ISSN: 1573-4838
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Technology
    Notes: Two methacrylate orthopaedic bone cements were compared as delivery systems for bioactive human growth hormone (hGH). These were London Hospital Bone Cement (LHBC) and a poly(methylmethacrylate) (PMMA) bone cement. A uniquely precise bioassay for hGH, named ESTA, was used. It was adapted to assess both the bioactivity of the hormone released from hGH loaded cements and also the in vitro cytotoxicity of the cements themselves. Eluates from both cements proved cytotoxic, this being most pronounced for LHBC. The cytotoxicity could be readily diluted out, and a lengthy exposure time (〉 24 h) was required to kill the cells. Both cements released similar quantities of bioactive hGH, which were ∼0.6% of that originally incorporated. This could potentially provide significantly high local concentrations of the hormone to the tissues surrounding the implant. Approximately double quantities of hormone were released as measured by immunoassay, leading to significant decreases (p=〈0.0001) in the B:I ratios of the released hormone. The effect was greatest for LHBC. Our results suggest that the structural integrity of the hGH molecules released from LHBC were the most compromised.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Journal of materials science 6 (1995), S. 676-679 
    ISSN: 1573-4838
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Technology
    Notes: Adult articular cartilage has a limited capacity for self-repair and a biomaterial to aid the process would be ideal. The polymer system, poly(ethyl methacrylate)/tetrahydrofurfuryl methacrylate (PEMA/THFMA) has shown potential in a rabbit model for such a role. The ability of the polymer system to support chondrocytes in vitro was investigated by light microscopy, transmission electron microscopy and biochemical assays. The PEMA/THFMA system maintained chondrocytes in agarose in a viable state with more glycosaminoglycan (GAG) produced per unit DNA after 14 days in culture compared to the tissue culture plastic control. Chondrocytes remained rounded on the polymer system surface as opposed to well spread on the Thermanox. The PEMA/THFMA system has been shown to be biocompatible for bovine chondrocytes maintaining them in a differentiated state with enhanced GAG production.
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