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  • 1
    Monograph available for loan
    Monograph available for loan
    London [u.a.] : Academic Press
    Call number: G 7417 ; 10267 ; M 93.0226 ; G 7090
    Type of Medium: Monograph available for loan
    Pages: IX, 484 S. : graph. Darst.
    ISBN: 0120734508
    Location: Upper compact magazine
    Location: Upper compact magazine
    Location: Upper compact magazine
    Location: Upper compact magazine
    Branch Library: GFZ Library
    Branch Library: GFZ Library
    Branch Library: GFZ Library
    Branch Library: GFZ Library
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  • 2
    Publication Date: 2005-03-26
    Description: Sites of transcription of polyadenylated and nonpolyadenylated RNAs for 10 human chromosomes were mapped at 5-base pair resolution in eight cell lines. Unannotated, nonpolyadenylated transcripts comprise the major proportion of the transcriptional output of the human genome. Of all transcribed sequences, 19.4, 43.7, and 36.9% were observed to be polyadenylated, nonpolyadenylated, and bimorphic, respectively. Half of all transcribed sequences are found only in the nucleus and for the most part are unannotated. Overall, the transcribed portions of the human genome are predominantly composed of interlaced networks of both poly A+ and poly A- annotated transcripts and unannotated transcripts of unknown function. This organization has important implications for interpreting genotype-phenotype associations, regulation of gene expression, and the definition of a gene.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Cheng, Jill -- Kapranov, Philipp -- Drenkow, Jorg -- Dike, Sujit -- Brubaker, Shane -- Patel, Sandeep -- Long, Jeffrey -- Stern, David -- Tammana, Hari -- Helt, Gregg -- Sementchenko, Victor -- Piccolboni, Antonio -- Bekiranov, Stefan -- Bailey, Dione K -- Ganesh, Madhavan -- Ghosh, Srinka -- Bell, Ian -- Gerhard, Daniela S -- Gingeras, Thomas R -- New York, N.Y. -- Science. 2005 May 20;308(5725):1149-54. Epub 2005 Mar 24.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Affymetrix Inc., Santa Clara, CA 95051, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/15790807" target="_blank"〉PubMed〈/a〉
    Keywords: Cell Line ; Cell Line, Tumor ; Cell Nucleus/metabolism ; Chromosomes, Human/*genetics ; Chromosomes, Human, Pair 13/genetics ; Chromosomes, Human, Pair 14/genetics ; Chromosomes, Human, Pair 19/genetics ; Chromosomes, Human, Pair 20/genetics ; Chromosomes, Human, Pair 21/genetics ; Chromosomes, Human, Pair 22/genetics ; Chromosomes, Human, Pair 6/genetics ; Chromosomes, Human, Pair 7/genetics ; Chromosomes, Human, X/genetics ; Chromosomes, Human, Y/genetics ; Computational Biology ; Cytosol/metabolism ; DNA, Complementary ; DNA, Intergenic ; Exons ; Female ; *Genome, Human ; Humans ; Introns ; Male ; Molecular Sequence Data ; Nucleic Acid Amplification Techniques ; Oligonucleotide Array Sequence Analysis ; Physical Chromosome Mapping ; RNA Splicing ; RNA, Messenger/*analysis ; *Transcription, Genetic
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 3
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 201 (1964), S. 599-599 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Obviously the Keshya problem will not be resolved with the present data and it would seem wise to postpone further speculation along such lines until we have knowledge of the isotopic composition of strontium in many more carbonate rocks, particularly those veins and vein-dykes not directly ...
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Contributions to mineralogy and petrology 23 (1969), S. 136-139 
    ISSN: 1432-0967
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Abstract Newly-discovered carbonatitic fragments from the West Eifel are described in terms of their petrography and trace-element content.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 330 (1987), S. 706-706 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] TRADITIONALLY, the main concern of geology has been with the Earth's crust, constituting less than 1 per cent of the planet's volume. Most of the Earth (84 per cent) is made up of the underlying mantle, and in recent years there have been international efforts to explore its composition (as ...
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 296 (1982), S. 525-530 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Mantle fragments carried up from as deep as 200km by high-velocity eruptions show metasomatic introduction of volatile bearing minerals, before melting. The broad spatial and temporal distribution of alkaline magmatism shows that transfer of lithophile elements to the outer Earth by rising ...
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 248 (1974), S. 267-268 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] SIR,-Some of the 'flaws'1 in my lateral compression model2 seem to be matters of faith, for example, that the model is "at odds with modern global tectonics", whilst many (including the "petrological observations") are arguable matters of interpretation. One "flaw", apparently supported by data, ...
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 338 (1989), S. 415-418 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Volcanism in the Rufunsa region was approximately contemporaneous with the Chilwa Alkaline Province in Malawi (early Cretaceous, 135-105 Myr ago)7, and during the activity the three major centres were intruded by coarse-grained carbonatites, similar in all essentials to the classic intrusive ...
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Contributions to mineralogy and petrology 50 (1975), S. 47-48 
    ISSN: 1432-0967
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Contributions to mineralogy and petrology 28 (1970), S. 340-351 
    ISSN: 1432-0967
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Abstract Eleven new analyses and modes of comendite obsidians are presented, and compared with all available data on similar rocks. Most specimens are aphyric or contain only sparse phenocrysts, most commonly alkali feldspar. The oxides SiO2, Al2O3, Na2O and K2O total over ninety percent by weight in all analyses. Iron, as FeO, is the only other constituent rising above one percent by weight. When the analyses are projected into the system Na2O-K2O-Al2O3-SiO2, oceanic and continental samples group differently. Oceanic specimens have a compositional spread ranging from trachytic to the quartz-feldspar cotectic zone, consistent with derivation through a trachyte magma stem. Continental comendites show a strong correlation with the experimentally determined quartz-feldspar minima along a path of increasing peralkalinity. These differences presumably reflect the contrasting environments of magma generation, and suggest an origin by partial melting within the continental crust for the continental comendite obsidians.
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