Publication Date:
2014-07-17
Description:
Article Dorsal membrane ruffles in macrophages accompany pathogen contact and appear before macropinocytosis and phagocytosis. Here, the authors show that these structures are the sites of the accumulation of Toll-like receptor 4 complexes involved in the signalling cascade activated by bacterial lipopolysaccharide. Nature Communications doi: 10.1038/ncomms5407 Authors: Lin Luo, Adam A. Wall, Jeremy C. Yeo, Nicholas D. Condon, Suzanne J. Norwood, Simone Schoenwaelder, Kaiwen W. Chen, Shaun Jackson, Brendan J. Jenkins, Elizabeth L. Hartland, Kate Schroder, Brett M. Collins, Matthew J. Sweet, Jennifer L. Stow
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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