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  • 1
    Keywords: Natural disasters. ; Environmental sciences Social aspects. ; Physical geography. ; Political science. ; Natural Hazards. ; Environmental Social Sciences. ; Earth System Sciences. ; Governance and Government.
    Description / Table of Contents: Report on the 4th Global Summit of Research Institutes for Disaster Risk Reduction (4thGSRIDRR2019) -- Enhancing disaster preparedness and building resilience: UNESCO's multi-hazard, multi-disciplinary, and multi-stakeholder approach on Disaster Risk Reduction -- Presentation on “The Sendai Framework and Science Advice to Governments to Support Implementation – Suggestion on What Works” -- Presenting the “Global Risk Assessment Framework (GRAF), UNISDR – Emphasising the Relevance of Disaster Research Institutes” -- DRMKC: A collaborative approach to foster resilience -- INFRASTRUCTURE RESILIENCE: A FRAMEWORK FOR ASSESSMENT, MANAGEMENT AND GOVERNANCE -- Harnessing Scientific Knowledge and Technological Innovation for Disaster Risk Reduction (DRR) in Sub-Saharan Africa-Case of Social Media -- Concept Notes for Group Discussion Sessions -- Community resilience against flood: the case of the LIFE PRIMES project -- Yonmenkaigi System Method as an Educational Framework for Climate Change within the United Kingdom: A Pilot Study -- Personalizing a Low cost weather forecasting system -- Transforming Flood Risk Management: A Case of Kakching, Manipur, India -- Adaptive Architecture- A Pathway to Resilient Communities -- RETURN PERIOD ANALYSIS OF MAJOR FLOOD EVENTS CONSIDERING HOMOGENEOUS REGIONS -- Conceptual Design for Flood Warning Study at Recreational Area – Case study Gunung Pulai Mountain, Johor, Malaysia -- IMPACT OF VIBRATION AND MOISTURE CONTENT TO LIGHT NON-AQUEOUS PHASE LIQUID MIGRATION IN DOUBLE POROSITY MEDIA -- Resolution of the 4th Global Summit of Research Institutes for Disaster Risk Reduction: Increasing the Effectiveness and Relevance of our Institutes Held at the Disaster Prevention Research Institute (DPRI), Kyoto University, Kyoto, Japan from 13th to 15th March 2019 -- Closing Ceremony. .
    Abstract: This book presents selected papers by the keynote speakers and other presenters from various disciplines and includes their opinions and evaluations. The Fourth Global Summit of Research Institutes for Disaster Risk Reduction (4th GSRIDRR, 2019): Increasing the Effectiveness and Relevance of our Institutes, sponsored by the Global Alliance of Disaster Research Institutes (GADRI) and Kyoto University, was hosted by and held at the Disaster Prevention Research Institute (DPRI), Kyoto University, Uji Campus, Kyoto, Japan, 13–15 March 2019.. The Global Summit series provided a platform for researchers, practitioners, policy makers, and other stakeholders in both government and non-governmental institutes involved in disaster risk reduction and resilience to come together to discuss, share, and exchange ideas. It focuses specifically on contributing input to the contextualization and revision of the goals of the 2016 Science and Technology Roadmap to implementation of the Priority Areas of the Sendai Framework for Disaster Risk Reduction Agenda 2015–2030, with input for GADRI to move forward in its contributions to the worldwide science community. The conference comprised an impressive array of global stakeholders whose expertise and experience encompassed the management of knowledge and its application for governments and industries, with shared outcomes to bridge science and decision making. It enhanced a process to confront new scientific challenges in disaster risk reduction and disaster risk management. The conference accomplished the following major goals, among others: (1) engagement in dialogue on issues related to disaster prevention and contributions to the Science and Technology Roadmap adopted to support the implementation of the Sendai Framework Agenda 2015–2030; (2) evaluation of current efforts on global and national involvement in the field of disaster prevention research in relation to the implementation of the Priority Areas of the Sendai Framework for Disaster Risk Reduction 2015–2030; (3) assessment of the status of current research knowledge and efforts, and research results at the institutional level in each country.
    Type of Medium: Online Resource
    Pages: XXI, 330 p. 113 illus., 104 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811955662
    Series Statement: Disaster and Risk Research: GADRI Book Series,
    DDC: 551
    Language: English
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  • 2
    Keywords: Natural disasters. ; Sustainability. ; Security systems. ; Climatology. ; Political science. ; Natural Hazards. ; Sustainability. ; Security Science and Technology. ; Climate Sciences. ; Governance and Government.
    Description / Table of Contents: Part 1: Overiview of the 3rd Global Summit of Research Institutes for Disaster Risk Reduction -- Chapter 1. Summary report of the 3rd Global Summit of Research Institutes for Disaster Risk Reduction: Expanding the Platform for Bridging Science and Policy Making (GSRIDRR 2017) held at the Disaster Prevention Research Institute (DPRI), Kyoto University, Kyoto, Japan from 19th to 21st of March 2017 -- Chapter 2. Evaluating Current Research Status and Identifying Most Important Future Research Themes -- Part 2: Selected Papers from Keynote Speeches -- Chapter 3. Regional Science Engineering Technology and Innovation (SETI) Support for Disaster Risk Reduction -- Chapter 4. Science and technology commitment to the implementation of the Sendai Framework for Disaster Risk Reduction 2015-2030 -- Chapter 5. Practical Point of View from Donors: “What we expect from science and technology group” – Application to Developing Countries -- Chapter 6. Knowledge to Sustainable Practices: International Network for Transdisciplinary Education (INATE) Approach -- Chapter 7. Disaster Risk Management Knowledge Centre: a new European Initiative to Bridge Science and Policy -- Part 3: Selected Papers from Presentations (arranged in country alphabetical order) -- Chapter 8. International Federation for Information Processing and its Domain Committee on Information Technology in Disaster Risk Reduction -- Chapter 9. Research Capacity in Disaster Risk Reduction – an Indian Perspective -- Chapter 10. Participatory Flood Risk Mapping - How Participatory is It? -- Chapter 11. Grant for Global Sustainability Project: Enhancing the Urban Disaster Resilience of Kathmandu and Yangon through Local Participatory Platform Activities -- Chapter 12. Seismic Vulnerability Assessment of Existing RC Buildings in Ranau, Sabah Malaysia -- Chapter 13. Large Landslides in México in the Past 10 Years -- Chapter 14. Disaster Risk Reduction (DRR) and Management under a Changing Climate: Bridging the Divide through Integrated Coastal Management (ICM) towards Sustainable Development -- Chapter 15. Landslide Disaster Management in Sri Lanka -- Chapter 16. Framework to Promote Multi-disciplinary Culture of Landslide Studies and Management -- Chapter 17. Disaster Resilient Infrastructure -- Chapter 18. Drought Disaster in the Central Highlands of Vietnam: Relationship Between Land-use Change and Drought’s Impact.
    Abstract: This book presents selected papers from the 3rd Global Summit of Research Institutes for Disaster Risk Reduction – Expanding the Platform for Bridging Science and Policy Making, which was held at the Disaster Prevention Research Institute (DPRI), Kyoto University, Uji Campus from 19 to 21 March 2017. It was organised by the Global Alliance of Disaster Research Institutes (GADRI), which was established soon after the second Global Summit and the UN World Conference on Disaster Risk Reduction in March 2015, and is intended to support the implementation of the Sendai Framework for Disaster Risk Reduction 2015–2030. The conference not only provided a platform for discussion and exchange of information on key current and future research projects on disaster risk reduction and management, but also promoted active dialogues through group discussion sessions that addressed various disaster research disciplines. In this book, authors from various disciplines working at governmental and international organisations provide guidance to the science and technical community, discuss the current challenges, and evaluate the research needs and gaps in the context of climate change, sustainable development goals and other interlinked global disaster situations. Expert opinions from practitioners and researchers provide valuable insights into how to connect and engage in collaborative research with the international science and technical communities and other stakeholders to achieve the goals set out in the agenda of the Sendai Framework for Disaster Risk Reduction 2015–2030. In addition, case studies and other evidence-based research papers highlight ongoing research projects and reflect the challenges encountered in information sharing by various stakeholders in the context of disaster risk reduction and management. Chapter “Science and technology commitment to the implementation of the Sendai Framework for Disaster Risk Reduction 2015-2030” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com. .
    Type of Medium: Online Resource
    Pages: XI, 250 p. 107 illus., 104 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811586620
    Series Statement: Disaster and Risk Research: GADRI Book Series,
    DDC: 551
    Language: English
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  • 3
    ISSN: 1546-1718
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] The genome-wide distribution of linkage disequilibrium (LD) determines the strategy for selecting markers for association studies, but it varies between populations. We assayed LD in large samples (200 individuals) from each of 11 well-described population isolates and an outbred European-derived ...
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1572-9931
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract CHO-UV-1 is a mutant of the Chinese hamster cell CHO-K1 hypersensitive to killing by ultraviolet light but with normal resistance to X-ray. It is also hypersensitive to killing by ethyl methane sulfonate. Hybrid clones formed by fusing UV-1 and Chinese hamster lung cells display the normal ultraviolet resistance of the latter. The sensitive phenotype behaves, therefore, in a genetically recessive manner. Ultraviolet sensitivity of UV-1 is not associated with a deficiency in excision repair. Alkaline sucrose gradient sedimentation analysis of nascent DNA from ultraviolet-irradiated cells reveals that UV-1 is, however, markedly deficient in postreplication recovery. Further, UV-1 has a lower rate of induced mutation to 6-thioguanine resistance than does the parental cell when treated with ultraviolet light or ethyl methane sulfonate. These results suggest that the phenotype of UV-1 is due to a mutation in a form of postreplication recovery which in normal cells is error prone.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Methods in cell science 10 (1986), S. 209-214 
    ISSN: 1573-0603
    Keywords: replica plating ; human cells ; nitrocellulose
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Replica plating, i.e., the production of multiple copies of a pattern of colonies derived from single cells, can now be applied to human cell lines using polyester mesh as a substrate. In searching for somatic cell mutants, often the only means of identifying a mutant clone is an assay that leaves the selected cells nonviable. With replica plating it is possible to retrieve that clone from the corresponding position on the replica. In addition, DNA from the colonies on the polyester replica can be transferred to nitrocellulose, facilitating the identification of clones using radioactive tracers or DNA probes.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1436-6215
    Keywords: Key words Carotenoids – oxidative DNA damage – DNA repair – comet assay
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Medicine
    Notes: Summary Background: Many epidemiological studies have identified a protection against cancer associated with consumption of fruit and vegetables. One factor is this protection may be the enhancement of cellular DNA repair activity by micronutrients, such as carotenoids, found in these foods. Aims of the study: To measure the capacity of lymphocytes isolated from volunteers supplemented with β-carotene, lutein or lycopene to recover from DNA damage induced in vivo by treatment with H2O2. Methods: Healthy volunteers were given supplements of lutein (15 mg/day), lycopene (15 mg/day) and βcarotene (15 mg/day), each for 1 week, the supplementation periods being separated by 3-week wash-out periods. Blood samples were taken at the beginning and end of each supplementation, and at 1 week and 3 weeks during the wash-out period. Carotenoid levels were measured in plasma. Lymphocytes were isolated and frozen. Subsequently, they were treated with 100 μM H2O2 and incubated for up to 24 h; DNA damage was measured with the comet assay (single cell gel electrophoresis) after 0, 2, 4, 8, and 24 h. Results: Increases of 2- to 3-fold in mean plasma lutein and β-carotene concentrations were seen at the end of the respective supplementation periods; they returned virtually to basal levels after wash-out. Lycopene concentrations were less affected by supplementation, and were more variable. H2O2-induced DNA strand breaks were apparently only slowly rejoined by the lymphocytes. The rejoining of breaks in the first few hours appeared substantially faster in lymphocytes following supplementation with β-carotene, but no such effect was seen with lutein. In those individuals who showed increases in lycopene concentrations, the recovery was significantly faster. Lymphocytes that were not treated with H2O2 showed a transient increase in DNA breakage to about double the background level in 2 h, presumably as a result of exposure to atmospheric oxygen; this effect, too, was relieved by supplementation with lycopene or β-carotene. Conclusions: While certain carotenoids appear to enhance recovery from oxidative damage, this is probably in fact an antioxidant protective effect against additional damage induced by atmospheric oxygen, rather than a stimulation of DNA repair.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Electrophoresis 16 (1995), S. 1670-1677 
    ISSN: 0173-0835
    Keywords: Likelihood ratios ; Quality control ; Population structure ; Matching probability ; Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Quality control for likelihood ratio (LR) tests on restriction fragment length polymorphisms (RFLPs) and polymerase chain reaction (PCR) markers is provided by the 4N6 program. Examples are given for tests of exclusion, coincidence, and kinship that should be used routinely in validation of DNA profiling. They confirm that “in a knowledgeable court DNA profiling is no longer exposed to risk of illogical presentation, blind acceptance or arbitrary rejection” (N. E. Morton, Eur. J. Hum. Genet. 1993, 1, 172-179). However, they remain to be implemented in national systems of quality control. There can be no effective quality control until attempts to fudge gene frequencies in order to retain the Hardy-Weinberg assumption (recommended by the National Research Council) are abandoned in favour of the population genetic approach that takes gene frequencies from a real population and uses kinship to express genotype probabilities. Since an expert witness cannot know the identity of the culprit, he is obliged to consider multiple hypotheses without usurping the prerogative of the court to favour one of them on the basis of other evidence. It remains to be seen whether the new NRC Committee (and more importantly the international community of forensic scientists) will adopt this fundamental principle, which is especially important in populations like India with preferential endogamy and consanguineous marriages. Alternative procedures and the causes, effects, and remedies of four types of error are also considered.
    Additional Material: 10 Tab.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1432-1777
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Cellular Physiology 99 (1979), S. 125-137 
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Cultured cells of Microtus agrestis, the common field vole, perform unscheduled DNA synthesis after UV irradiation. They respond to incubation with a DNA synthesis inhibitor (1-β-D-arabinofuranosylcytosine) following UV in ways typical of cells capable of excision repair, with reduced survival and an accumulation of breaks in pre-existing DNA.Microtus cells irradiated with UV in a quiescent pre-S-phase state are more sensitive to UV than are proliferating cells, in terms of survival. Adding DNA precursors (deoxyribonucleosides), and - in the case of proliferating cells - growing in complete rather than dialysed serum, enhance UV survival.Quiescent cells show a higher rate of endonucleolytic incision of DNA after UV than do proliferating cells.The balance between incision (producing single-strand DNA breaks) and repair DNA synthesis (leading to rejoining of breaks) is shifted by the addition of deoxyribonucleosides, which suggests that DNA precursor supply is a rate-limiting factor in repair. The lower survival of quiescent cells (in the absence of added deoxyribonucleosides) may be due to insufficient precursor supply to meet the demands of the high incision rate.
    Additional Material: 10 Ill.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 0044-8249
    Keywords: Käfigverbindungen ; Selbstorganisation ; Supramolekulare Chemie ; Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
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