ISSN:
1013-9826
Source:
Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
Topics:
Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
Notes:
Resorbable osteosynthesis based on PLLA and derivatives will be associated to bonesubstitute for bone reconstruction. We have performed rand evaluated a composite combining PLDLLA and Biphasic calcium phosphate able to have a), a better controlled hydrolysis in the purposeto preserve on time the mechanical property, and b), for long term efficiency, bone ingrowth at theexpense of the osteosynthesis and the associated bone substitute. A new calcium phosphate cementMCPC® was tested with such composite. The novel macroporous calcium phosphate cementMCPC sets to poorly crystalline apatite after mixing the powder component and an aqueoussolution. Interconnective macroporosity was induced on time by resorption of one part of theMCPC®. The multiphasic calcium phosphate components in the cement, are resorbed at differentrates allowing the replacement by newly formed bone. This study reports the biocompatibility andthe interactions of a composite using PL DLLA (Poly [L-Lactide-co-D,L-Lactide] acid) chargedwith biphasic calcium phosphate granules and a self setting calcium phosphate cement of newgeneration
Type of Medium:
Electronic Resource
URL:
http://www.tib-hannover.de/fulltexts/2011/0528/01/56/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.361-363.411.pdf
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