ISSN:
1420-9071
Keywords:
Tuberoinfundibular dopaminergic system
;
prolactin
;
estrogen-treated rats
;
prolactin secreting adenoma
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary Hypothalamic fragments from female rats treated repeatedly with estradiol valerate (EV) and bearing prolactin (PRL)-secreting tumors contained, seven months after the last EV injection, lower concentrations of dopamine (DA) than age-matched controls. Depolarizing concentrations of K+ (35 mM) and amphetamine (50 μM) evoked in PRL-secreting tumor bearing rats an endogenous DA release significantly lower than in controls.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02118641
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