Analytical Chemistry and Spectroscopy
Wiley InterScience Backfile Collection 1832-2000
Chemistry and Pharmacology
Mixtures of 50% tetramethylsilane (TMS) and methane have been found to give [M+73]+ adduct ions and structurally useful fragment ions for many oxygen- and nitrogen-containing organic compounds. All of the reagent ions in TMS react with polar compounds. The high-pressure TMS chemical ionization spectra of many simple oxygenated compounds are in agreement with predictions from ion chemistry of (CH3)3Si+ obtained by ion cyclotron resonance experiments at very low pressures, but differences are noted. Sensitivities for oxygen-, nitrogen-, and sulfur-containing compounds with TMS as the reagent gas appear to be approximately the same.
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