ISSN:
1420-9071
Keywords:
Engelhardtia chrysolepis
;
astilbin
;
neoastilbin
;
taxifolin
;
aldose reductase
;
aldehyde reductase
;
NADH oxidase
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract Astilbin and neoastilbin, dihydroflavonol rhamnosides fromEngelhardtia chrysolepis, showed potent inhibition of lens aldose reductase. Kinetic analysis showed astilbin exhibited uncompetitive inhibition against bothdl-glyceraldehyde and NADPH. These taxifolin glycosides were selective inhibitors of aldose reductase with no inhibition of NADH oxidase.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01969729
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