ISSN:
1013-9826
Source:
Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
Topics:
Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
Notes:
To investigate the mechanical property (shear strength, bending strength and compressivestrength) and the interface combinative ability of the composite of bovine bone morphogeneticprotein (bBMP) and porous hydroxyapatite (HA) with different pore diameter. HA1 (Φ100-300μm)and HA2 (Φ130-500μm) were used as carriers of bBMP(5mg). The 4 types material (HA1, HA2,bBMP /HA1, bBMP /HA2) were implanted into the femur of 10 dogs (2 dogs each group) for theshear test and 15 dogs (3 dogs each group) for the bending test and compressive test. The shearstrength of all kinds of materials were increased as time went on and the shear strength ofbBMP/HA1 was highest in four materials. The bending strength of bBMP /HA1 was close to thenormal femur in the 24th week. The compressive strength of all materials was lower than the cortexof the dog’s femur until 24th week. The compressive strength of bBMP /HA1 was the highest in fourtypes. The compressive strength of HA2 and bBMP /HA2 was decreased after implantation. Implantof bBMP /HA with 100-300μm diameter had strong bonding with the host bone, and had bettermechanical properties than that with 130-500μm diameter. So the porous bBMP /HA (Φ100-300μm ) could be a useful graft material due to its strength
Type of Medium:
Electronic Resource
URL:
http://www.tib-hannover.de/fulltexts/2011/0528/01/53/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.330-332.1193.pdf
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