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  • 1
    ISSN: 1432-1041
    Keywords: Fenspiride ; pharmacokinetics ; bioavailability
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The absolute bioavailability of fenspiride has been studied in twelve healthy volunteers. It was administered IV and orally in single doses of 80 mg fenspiride hydrochloride according to a randomised crossover pattern. Following IV administration, the plasma clearance of fenspiride was about 184 ml·min−1, and its apparent volume of distribution was moderately large (2151). When given orally as a tablet, fenspiride exhibited fairly slow ab- sorption; the maximum plasma concentration (206 ng·ml−1) was achieved 6 h after administration. The absolute bioavailability was almost complete (90%). The tablet had slow release characteristics. The elimination half-life obtained from the plasma data was 14 to 16 h independent of the route of administration.
    Type of Medium: Electronic Resource
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  • 2
    Publication Date: 2018-12-14
    Description: Highlights • Northern Hispaniola Margin is studied with new high-resolution bathymetry and vintage seismic data. • Northern Hispaniola Deformed Belt forms an active N-verging fold-and-thrust imbricate system. • Gravity failures are frequent features in the Northern Hispaniola Margin and Bahamas Banks slope. • Oblique collision accelerates the Bahamas Carbonate Province collapse and retreat. • New observations help the assessment of tsunami hazards in the Northern Caribbean region. Abstract The northern margin of Hispaniola records the oblique collision/underthrusting of the Bahamas Carbonate Province with the island-arc. Due to the collision, northern Hispaniola has suffered several natural disasters caused by major earthquakes and tsunamis, such as the historic earthquake of 1842, the tsunami caused by earthquake-driven slumping in 1918 in the Mona Passage, the seismic crisis of 1943–1953 with five events of M 〉 7.0 or the seismic crisis of 2003 with a main shock of M6.3 and a large aftershock of M5.3. Using new swath multibeam bathymetry data and vintage single- and multi-channel seismic profiles, we have performed a regional scale analysis and interpretation of the shallow surface and active processes along the northern margin of the Dominican Republic. We have identified three morphostructural provinces: a) the Bahamas Banks, b) the Hispaniola Trench and c) the Insular Margin, which are divided into two tectonic domains, the Collision Domain and Underthrusting Domain. The southern slope of the Bahamas Carbonate Province shows a very irregular morphology produced by active erosive processes and normal dip-slip faulting, evidence of an extensional tectonic regime and margin collapse. This collapse is of major extent in the Oblique Collision Domain where there are erosive and fault escarpments with higher dip-slip fault throws. The Hispaniola Trench, is formed by the Caicos and Hispaniola basins in the underthrusting domain, and by the Santisima Trinidad and Navidad basins in the Oblique Collision Domain. They have a flat seafloor with a sedimentary filling of variable thickness consisting of horizontal or sub-horizontal turbiditic levels. The turbiditic fill mostly proceeds from the island arc through wide channels and canyons, which transports sediment from the shelf and upper slope. The Insular Margin comprises the Insular Shelf and the Insular Slope. The active processes are generated on the Insular Slope where the Northern Hispaniola Deformed Belt is developed. This Deformed Belt shows a very irregular morphology, with a WNW-ESE trending N verging imbricate thrust-and fold system. This system is the result of the adjustment of the oblique collision/underthrusting between the North American plate and the Caribbean plate. In the Oblique Underthrusting Domain the along-strike development of the imbricate system is highly variable forming salients and recesses. This variability is due to along-strike changes in the sediment thickness of the Hispaniola Trench, as well as to the variable topography of the underthrusting Bahamas Carbonate Province. In the Oblique Collision Domain, the morphology of the Insular Slope and the development of the Deformed Belt deeply change. The imbricate system is barely inferred and lies upslope. These changes are due to the active collision of Bahamas Carbonate Province with the Insular Margin where the spurs are indented against the Insular Margin. Throughout the entire area studied, gravitational instabilities have been observed, especially on the Insular Margin and to a lesser extent on the southern slope of the Bahamas Carbonate Province. These instabilities are a direct consequence of the active underthrusting/collision process. We have mapped large individual slumps north of Puerto Plata in the Oblique Underthrusting Domain and zones of major slumps in the Oblique Collision Domain. These evidences of active processes must be considered as near-field sources in future studies on the assessment of tsunami hazards in the region.
    Type: Article , PeerReviewed
    Format: text
    Format: text
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  • 3
    ISSN: 1434-601X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Zusammenfassung Vergleich der empirischen Rydbergschen Nenner in der Eisenreihe und der Beziehungen zwischen ihnen mit den Ergebnissen der Slaterschen Theorie der Atomspektren.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1434-601X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    The European physical journal 35 (1926), S. 449-463 
    ISSN: 1434-601X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Zusammenfassung Das Pd-Bogenspektrum hat ungerade Vielfachheiten: Triplett- und Singuletterme werden sichergestellt. Der Grundterm ist ein Singulett-S-Term mit j=0. Pd-Konfiguration vermutlich stabiler als die von Ni und Pt. Versuch einer Zuordnung von Azimutalquanten zu den Termen. Grundterm von Pd+ wahrscheinlich2D. Vergleich der Eisenreihe mit der Palladiumreihe; Grundterme bei chemischen Analogen nicht immer gleich. Versuch einer Érklärung der Grundterme der Pd-Reihe. Magnetonenkurve.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1434-601X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Zusammenfassung 1. Beziehung zwischen den Aufspaltungen von Termen gleicher k-Anordnung in beliebigem Bogenspektrum und Funkenspektrum des in der Horizontalreihe des periodischen Systems folgenden Elements, Beispiele. 2. Die Abweichungen von der Intervallregel erfolgen bei solchen einander entsprechenden Termen im selben Sinn. 3. Bei einander entsprechenden Termen verschiedener Multiplizität, aber desselben Spektrums, wachsen die Δv wie 1/r an, wenn bei beiden Multiplizitäten Aufspaltungen zwischen denselben j verglichen werden; diese Regel kann keinen weiteren Geltungsbereich haben als die Intervallregel von Landé, Beispiele. 4. Bemerkung über die Aufspaltungen von Termen derselben Konfiguration und Multiplizität, aber verschiedener l-Werte.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    The European physical journal 47 (1928), S. 89-113 
    ISSN: 1434-601X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Zusammenfassung Neue Terme der drei Niveaugruppen (tiefe, mittlere und hochliegende Terme) des Spektrums werden nachgewiesen, sie gehören dem Dublett- und Quartettsystem an. Durch Kombination dieser Terme untereinander und mit den bereits bekannten des Spektrums konnten mehr als 700 Linien neu eingeordnet werden, so daß nunmehr im Co-Bogen rund 1200 Linien klassifiziert sind. Die tiefen Terme gehören zu mindestens zwei verschiedenen Konfigurationen der Außenelektronen, nämlich zu d7s2 und d8s1. Sie sind in Übereinstimmung mit der Voraussage der Theorie von Hund.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    The European physical journal 32 (1925), S. 336-369 
    ISSN: 1434-601X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Zusammenfassung In Übereinstimmung mit F. M. Walters finden wir im Co-Bogenspektrrm geradzahlige Struktur. — Es werden Dublett-, Quartett-, Sextetterme nachgewiesen. Der Grundterm ist ein f-Term des Quartettsystems (bestätigt durch Absorptionsaufnahmen von v. Angerer und Joos). Alle Terme sind verkehrt; das magnetische Moment des Co-Atoms beträgt im Grundzustand sechs Bohrsche Magnetonen. Eine neue Form des Auswahlprinzips für die Azimutalquantenzahl wird angegeben. Das Niveauschema des Spektrums zeigt große Ähnlichkeit mit dem des Fe; die Terme sind auffallend regelmäßig gelagert. Zusammen sind bis jetzt 517 Linien eingeordnet.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 114 (1924), S. 192-193 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] IN a letter to NATURE of June 21, p. 889, I have shown the existence of a numerical relation between the pressure displacements of the lines of the iron spectrum, the temperature class of the lines, and the magnitude of the spectral terms which originate those lines by combination. It now seems ...
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  • 10
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 113 (1924), S. 889-891 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] IT has been long recognised that the lines of the iron spectrum are displaced towards the red when the pressure about their source is increased, the magnitude of the displacement being not the same for all the lines. On account of this fact Gale and Adams (Astrophys. Journ. 35, 1912, p. 10) ...
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