ISSN:
1434-193X
Keywords:
Piperidines
;
Tricarbonyliron complexes
;
Asymmetric synthesis
;
Chiral resolution
;
Natural prioducts
;
Chemistry
;
General Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The first total asymmetric synthesis and the attribution of the absolute configurations of (+)-dienomycin C (1), an alkaloid isolated from a Streptomyces strain, are reported. This compound was prepared in six steps from the enantiopure tricarbonyl(dienal)iron complex (+)-4 which is easily obtained by separating preformed diastereomers, starting from phenylpentadienoic acid and (S)-methyl mandelate.
Additional Material:
1 Ill.
Type of Medium:
Electronic Resource
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