ISSN:
1476-4687
Source:
Nature Archives 1869 - 2009
Topics:
Biology
,
Chemistry and Pharmacology
,
Medicine
,
Natural Sciences in General
,
Physics
Notes:
[Auszug] Toxin molecules, such as Pseudomonas exotoxin A (PEA), kill a cell by inactivating the elongation factor-2 (EF-2) in the cytosol2'8, suggesting that mammalian cells can be genetically modified to produce and secrete targeted toxins by using a signal sequence to lead newly synthesized toxins into ...
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1038/385078a0
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