ALBERT

All Library Books, journals and Electronic Records Telegrafenberg

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Characteristics of in vitro ribonucleic acid synthesis by macronuclei of Tetrahymena pyriformis (1970)
    s.l. : American Chemical Society
    Biochemistry 9 (1970), S. 3947-3959 
    Details
    ISSN: 1520-4995
    Source: ACS Legacy Archives
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/bi00822a013
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Murine neuroblastoma cured in vivo by an antibody-dependent cellular cytotoxicity reaction (1976)
    [s.l.] : Nature Publishing Group
    Nature 264 (1976), S. 783-785 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Table I In vitro AC 〉CC agai nst MNB \ cells 51Cr % Specific Sample c.p.m. ±s.e. release MNB cells, control 1140 38 0 MNBcells+RSC 1055 81 0 MNB cells, freeze-thawed 2019 55 100 MNB cells -f AS 1 :50f RSC 1528 34 44 MNB cells + AS 1 :250+RSC 1570 44 49 ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/264783a0
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Non-coordinate Synthesis of Division-related m RNA (1968)
    [s.l.] : Nature Publishing Group
    Nature 218 (1968), S. 1271-1273 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Tetrahymena pyriformis GL was grown and synchronized in a media consisting of 1 per cent proteose-peptone (Difco), and 0-1 per cent sodium acetate, dibasic potassium phosphate and yeast extract (Difco). During the last cold period all cells were collected gently by centrifugation, washed three ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/2181271a0
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Bonding of Small Molecules to DNA following Ionizing Radiation (1970)
    [s.l.] : Nature Publishing Group
    Nature 225 (1970), S. 859-860 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] We have used both purified commercial calf thymus DNA (Calbiochem) and DNA purified from Tetrahymena pyriformis12. To demonstrate the formation of stable bonds after irradiation, DNA solutions containing labelled small molecules were irradiated in 2?3 mm depths using the electron beam of a Varian ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/225859a0
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Do Synchronizing Temperature Shifts Inhibit RNA Synthesis in Tetrahymena pyriformis? (1970)
    Oxford, UK : Blackwell Publishing Ltd
    The @journal of eukaryotic microbiology 17 (1970), S. 0 
    Details
    ISSN: 1550-7408
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: SYNOPSIS The effects of synchronizing temperatures on RNA metabolism in 2 strains of Tetrahymena pyriformis have been studied. High temperature shifts cause degradation of unstable RNA fractions, including whole cell RNA and nuclear RNA. The evidence indicates that this hydrolysis results in a net loss of unstable RNA during each temperature shift and, indirectly, to an inhibition of uptake2 of extra-cellular RNA precursors. The destruction of unstable RNA appears random; no evidence for stable template pools was found. In addition, both indirect in vivo and direct in vitro assays of RNA polymerase activity failed to reveal any inhibition by synchronizing heat shifts. The inhibition of precursor incorporation in vivo apparently stems from a lag in the uptake of label into the intracellular nucleotide pools. The temperature values required to induce net hydrolysis of unstable RNA correlate well with those required for synchronization for each strain.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1550-7408.1970.tb04712.x
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 6
    Electronic Resource
    Electronic Resource
    Carrier-dependent and carrier-independent transport of anti-cancer alkylating agents (1981)
    [s.l.] : Nature Publishing Group
    Nature 294 (1981), S. 281-283 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] An assay which uses the mitogen phytohaemagglutinin (PHA) to induce proliferation in tissue culture of human peripheral T lymphocytes7"9 was developed for these experiments10. It can be seen (Fig. 1) that 3H-thymidine uptake was very low before PHA stimulation but increased steadily (as measured by ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/294281a0
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 7
    Electronic Resource
    Electronic Resource
    Effects of methylated xanthines on mammalian cells treated with bifunctional alkylating agents (1980)
    [s.l.] : Nature Publishing Group
    Nature 285 (1980), S. 326-329 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The effects of caffeine on damaged human cells are less consistent than those on rodent cells16,21-24. Figure 1 shows the survival curves obtained when human HT-29 cells (ref. 25, human karyotype confirmed by K. Benirschke) were exposed to increasing concentrations of HN2 with or without a ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/285326a0
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 8
    Electronic Resource
    Electronic Resource
    5-Fluorouracil radiation sensitization — A brief review (1989)
    Springer
    Investigational new drugs 7 (1989), S. 111-116 
    Details
    ISSN: 1573-0646
    Keywords: 5-fluorouracil ; radiation ; radiosensitization ; pharmacology ; squamous cancers
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary 5-Fluorouracil (FUra) has emerged as the most promising clinical radiosensitizer now available. FUra's capacity to render human cells more sensitive to x-rays was established soon after its synthesis. However, the recognition that the drug's unusual pharmacology dictated explicit scheduling requirements in man was not realized until recently when work in the author's laboratory identified the extra-cellular drug concentration X time factors necessary to create the intra-cellular radiosensitive state. Subsequent clinico-pharmacologic investigations led to the realization that only prolonged continuous infusions combined with appropriately fractionated, cyclical radiation therapy would maximize the clinical utility of this approach. Infused FUra radiation-sensitization therapy reaches its maximum efficacy against the squamous-transitional cancers. This group of human malignancies comprises about 15% of all human cancers. Preliminary data also suggests substantial promise in the local/regional control of rectal and breast cancers. Infused FUra used as a radiosensitizer has the potential to eliminate the need for about 90% of all radical cancer surgery.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00178197
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 9
    Electronic Resource
    Electronic Resource
    Stability of division-related protein and nucleic acid fractions in synchronized Tetrahymena (1967)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Cellular Physiology 70 (1967), S. 265-273 
    Details
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The kinetics of RNA synthesis have been studied under various growth conditions using synchronized Tetrahymena pyriformis GL. The curves obtained are approximately linear in growth-supporting media but vary under other circumstances. The presence of amino acids in the medium stimulates RNA synthesis in Tetrahymena as it does in bacteria. Since these induced variations do not influence the essential features of the pre-cytokinetic period it is inferred that fluctuations in the rate of RNA synthesis described by others are probably not essential features of temperature-induced synchrony. In addition, the translational stability of division-related templates at synchronizing temperatures has been investigated. The synthesis of proteins necessary for cytokinesis is shown to be greatly reduced under conditions simulating a heat-shock. Inhibitor studies using cycloheximide indicate that protein synthesis is required longer into the cytokinetic phase than had previously been thought. Collectively the data are all compatible with the hypothesis that synthesis of division-related proteins is drastically reduced in heat-shocked Tetrahymena and that the basis for this reduction is hydrolysis of template RNA without concurrent translation.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jcp.1040700306
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 10
    Electronic Resource
    Electronic Resource
    Temperature dependent RNA decay in TetrahymenaSupported by grant GM 06461-07 from the United States Public Health Service. (1966)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Cellular Physiology 68 (1966), S. 203-205 
    Details
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jcp.1040680215
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...