ISSN:
0935-6304
Keywords:
Capillary gas chromatography (CGC)
;
Enantioselective separations
;
(2,3,6-Tri-O-methyl)-cyclodextrins
;
Interaction study
;
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The enantioseparation of some 2,2-dialkyl-4-alkoxycarbonyl-1,3-dioxolane derivatives, which are important intermediates in the total synthesis of a number of biologically active compounds, was studied by means of capillary gas chromatography (CGC). The chromatographic results, obtained on columns coated with permethylated α-, β- and γ-cyclodextrin respectively, are reported. Out of sixteen compounds, thirteen could be separated with a resolution superior to 1,2. One racemate could not be separated on any of the columns. Considerations concerning the separation mechanism are proposed.
Additional Material:
2 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jhrc.1240161206
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