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    Autophagy: clocking in for the night shift (2019)
    Springer Nature
    Details
    Publication Date: 2019
    Description: 〈p〉Daily rhythms of biological activity, such as cycles of sleep–wake and feeding–fasting, are coupled to cell-autonomous circadian clocks to synchronize organismal food intake with cellular bioenergetics. Food intake during wake stimulates biosynthesis followed by rest periods of autophagy, which degrades damaged macromolecules and recycles them as nutrients to enhance fitness. In this issue of 〈i〉The EMBO Journal〈/i〉, Pastore 〈i〉et al〈/i〉 discovered that regulators of autophagy, TFEB and TFE3, are activated during the rest phase and ultimately drive the expression of Rev-erbα, a component of the core circadian molecular clock, coupling autophagy and the clock.〈/p〉
    Print ISSN: 0261-4189
    Electronic ISSN: 1460-2075
    Topics: Biology , Medicine
    Published by Springer Nature on behalf of The European Molecular Biology Organization (EMBO).
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  • 2
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    Autophagy: clocking in for the night shift (2019)
    Springer Nature
    Details
    Publication Date: 2019
    Description: 〈p〉Daily rhythms of biological activity, such as cycles of sleep–wake and feeding–fasting, are coupled to cell-autonomous circadian clocks to synchronize organismal food intake with cellular bioenergetics. Food intake during wake stimulates biosynthesis followed by rest periods of autophagy, which degrades damaged macromolecules and recycles them as nutrients to enhance fitness. In this issue of 〈i〉The EMBO Journal〈/i〉, Pastore 〈i〉et al〈/i〉 discovered that regulators of autophagy, TFEB and TFE3, are activated during the rest phase and ultimately drive the expression of Rev-erbα, a component of the core circadian molecular clock, coupling autophagy and the clock.〈/p〉
    Print ISSN: 0261-4189
    Electronic ISSN: 1460-2075
    Topics: Biology , Medicine
    Published by Springer Nature on behalf of The European Molecular Biology Organization (EMBO).
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
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