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  • 1
    Monograph available for loan
    Monograph available for loan
    Integrated assessment of water resources and global change : a north-south analysis (2007)
    Dordrecht : Springer
    Details Availability
    Call number: PIK N 454-14-0221
    Description / Table of Contents: Contents: Shift in thinking to address the 21st century hunger gap ; A grid-based assessment of global water scarcity including virtual water trading ; Water footprints of nations: Water use by people as a function of their consumption pattern ; Transitions towards adaptive management of water facing climate and global change ; Stakeholder-driven, enquiry-driven, or stakeholder-relevant, enquiry-driven science? ; Learning Alliances for the broad implementation of an integrated approach to multiple sources, multiple uses and multiple users of water ; Possibilities and problems with the use of models as a communication tool in water resource management ; Integration of the biophysical and social sciences using an indicator approach: Addressing water problems at different scales ; Capturing the complexity of water uses and water users within a multi-agent framework ; Upscaling field scale hydrology and water quality modelling to catchment scale ; Linking databases of different sources and scales for groundwater research in the Urema River Basin/Central Mozambique ; Integrated water and food analysis at the global and basin level. An application of WATERSIM ; The adaptive integrated data information system (AIDIS) for global water research ; Policy implications of a pan-tropic assessment of the simultaneous hydrological and biodiversity impacts of deforestation ; Towards better water security in North China ; Towards transition management of European water resources ; Some foci of integrated water resources management in the 'South' which are oft-forgotten by the 'North': A perspective from southern Africa ; The GLOWA Volta Project: A framework for water resources decision-making and scientific capacity building in a transnational West African basin ; Integrating a climate change assessment tool into stakeholder-driven water management decision-making processes in California ; Involving stakeholders in integrated river basin planning in England and Wales ; Integrated assessment of water resources: Australian experiences
    Type of Medium: Monograph available for loan
    Pages: 373 S. : graph. Darst., Kt.
    ISBN: 9781402055904
    Location: A 18 - must be ordered
    Branch Library: PIK Library
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  • 2
    Electronic Resource
    Electronic Resource
    Impacts of Carbon and Flooding on Soil Microbial Communities: Phospholipid Fatty Acid Profiles and Substrate Utilization Patterns (1998)
    Springer
    Microbial ecology 35 (1998), S. 265-278 
    Details
    ISSN: 1432-184X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Phospholipid fatty acid (PLFA) profiles provide a robust measure that can be used to fingerprint the structure of soil microbial communities, and measure their biomass. A replicated field trial, with gradients in substrate and O2 availability created by straw incorporation and flooding was used to test the ability of PLFA to discriminate soil microbial communities in different management regimes. Another objective was to test the usefulness, on a large scale, of some of the proposed interpretations of PLFA biomarkers. Using a direct gradient statistical analysis method, PLFA profiles were found to be very sensitive to flooding and straw treatments. Relative abundances of monounsaturated fatty acids were reduced with flooding and increased with added carbon, consistent with their proposed interpretations as indicators of aerobic conditions and high substrate availability. The cyclopropyl fatty acids were not useful as taxonomic indicators of respiratory type, although their responses were consistent with their proposed use as growth condition indicators. Branched fatty acids decreased, as a group, in response to high substrate conditions. A specific biomarker for Type II methanotrophs was not found in this rice soil, even under high carbon, low O2 conditions, which resulted in methane exposure in the soil. Direct comparison of PLFA and substrate utilization patterns indicated that Biolog patterns are highly selective, and do not reflect compositional changes in soil communities.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002489900082
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  • 3
    Electronic Resource
    Electronic Resource
    Determinants of Soil Microbial Communities: Effects of Agricultural Management, Season, and Soil Type on Phospholipid Fatty Acid Profiles (1998)
    Springer
    Microbial ecology 36 (1998), S. 1-12 
    Details
    ISSN: 1432-184X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Phospholipid fatty acid (PLFA) profiles were measured in soils from organic, low-input, and conventional farming systems that are part of the long term Sustainable Agriculture Farming Systems (SAFS) Project. The farming systems differ in whether their source of fertilizer is mineral or organic, and in whether a winter cover crop is grown. Sustained increases in microbial biomass resulting from high organic matter inputs have been observed in the organic and low-input systems. PLFA profiles were compared to ascertain whether previously observed changes in biomass were accompanied by a change in the composition of the microbial community. In addition, the relative importance of environmental variables on PLFA profiles was determined. Redundancy analysis ordination showed that PLFA profiles from organic and conventional systems were significantly different from April to July. On ordination plots, PLFA profiles from the low-input system fell between organic and conventional systems on most sample dates. A group of fatty acids (i14:0, a15:0, 16:1ω7c, 16:1ω5c, 14:0, and 18:2ω6c) was enriched in the organic plots throughout the sampling period, and another group (10Me16:0, 2OH 16:1 and 10Me17:0) was consistently lower in relative abundance in the organic system. In addition, another group (15:0, a17:0, i16:0, 17:0, and 10Me18:0) was enriched over the short term in the organic plots after compost incorporation. The relative importance of various environmental variables in governing the composition of microbial communities could be ranked in the order: soil type 〉 time 〉 specific farming operation (e.g., cover crop incorporation or sidedressing with mineral fertilizer) 〉 management system 〉 spatial variation in the field. Measures of the microbial community and soil properties (including microbial biomass carbon and nitrogen, substrate induced respiration, basal respiration, potentially mineralizable nitrogen, soil nitrate and ammonium, and soil moisture) were seldom associated with the variation in the PLFA profiles.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002489900087
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  • 4
    Electronic Resource
    Electronic Resource
    In vitro synthesis of a lipid-linked acetylated and pyruvilated olicosaccharide in Rhizobium trifolii
    Amsterdam : Elsevier
    Biochemical and Biophysical Research Communications 134 (1986), S. 205-211 
    Details
    ISSN: 0006-291X
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/0006-291X(86)90548-6
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  • 5
    Electronic Resource
    Electronic Resource
    A novel class of nitrile ylide
    Amsterdam : Elsevier
    Tetrahedron Letters 27 (1986), S. 4643-4646 
    Details
    ISSN: 0040-4039
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/S0040-4039(00)85027-3
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  • 6
    Electronic Resource
    Electronic Resource
    The Salmonella typhimurium invasion genes invF and invG encode homologues of the AraC and PulD family of proteins (1994)
    Oxford, UK : Blackwell Publishing Ltd
    Molecular microbiology 13 (1994), S. 0 
    Details
    ISSN: 1365-2958
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: We have identified two novel Salmonella typhimurium genes, invF and invG, which are required for the efficient entry of these organisms into cultured epithelial cells. invF and invG are located immediately upstream of invE, a previously identified gene also required for Salmonella entry. Non-polar mutations in these genes rendered S. typhimurium severely deficient for entry into cultured epithelial cells. The nucleotide sequences of invF and invG indicated that these genes encode polypeptides with predicted molecular weights of 24373 and 62275, respectively. Proteins of similar sizes were observed when invF and invG were expressed in a bacteriophage T7 RNA polymerase-based expression system. Comparison of the predicted sequence of InvF with translated sequences in the existing databases indicated that this protein is homologous to members of the AraC family of prokaryotic transcription regulators. However, mutations in invF did not significantly affect the expression of other members of the inv locus. InvG was found to be homologous to members of the PuID family of specialized translocases. This homology suggests that InvG may be necessary for the export of invasion-related determinants or involved in the assembly of a supramolecular structure that promotes entry.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2958.1994.tb00450.x
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  • 7
    Electronic Resource
    Electronic Resource
    Cloning and molecular characterization of a gene involved in Salmonella adherence and invasion of cultured epithelial cells (1993)
    Oxford, UK : Blackwell Publishing Ltd
    Molecular microbiology 7 (1993), S. 0 
    Details
    ISSN: 1365-2958
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: Our laboratories have independently identified a gene in Salmonella choleraesuis and Salmonella typhimurium that is necessary for efficient adherence and entry of these organisms into cultured epithelial cells. Introduction of a mutated gene into several Salmonella strains belonging to different serotypes rendered these organisms deficient for adherence and invasion of cultured cells. This effect was most pronounced in the host-adapted serotypes Salmonella gallinarum, S. choleraesuis, and Salmonella typhi. The nucleotide sequence of this gene, which we have termed invH, encodes a predicted 147-amino-acid polypeptide containing a signal sequence. The InvH predicted polypeptide is highly conserved in S. typhimurium and S. choleraesuis, differing at only three residues. The invH gene was expressed in Escherichia coli using a T7 RNA polymerase expression system and a polypeptide of ∼16000 molecular weight was observed, in agreement with the predicted size of its gene product. Upon fractionation, the expressed polypeptide was localized in the bacterial membrane fraction. Southern and colony hybridization analyses indicated that the invH gene is present in all Salmonella strains tested (91 strains belonging to 37 serotypes) with the exception of strains of Salmonella arizonae. No homologous sequences were detected in Yersinia, Shigella, Proteus, and several strains of enteroinvasive and enteropathogenic E. coli. Downstream from the S. choleraesuis (but not S. typhimurium) invH gene, a region with extensive homology to the insertion sequence IS3 was detected.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2958.1993.tb01100.x
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  • 8
    Electronic Resource
    Electronic Resource
    Studies on Isocyanides and Related Compounds. A Facile Synthesis of Imidazo[1,5-a]imidazoles (1993)
    Weinheim : Wiley-Blackwell
    Liebigs Annalen 1993 (1993), S. 1229-1231 
    Details
    ISSN: 0170-2041
    Keywords: Isocyanide, 2,2-diethoxyethyl- ; Ugi four-component condensation (4CC) ; Spiroimidazo[1,5-a]imidazoles ; Selenium compounds ; Imidazo[1,5-a]imidazoles ; Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The Ugi four-component condensation between 1,1-diethoxy-2-isocyanoethane (2), cycloketones 1, amine hydrochlorides 4, and potassium thiocyanate (3a) or selenocyanate (3b) affords spiroimidazoles 5, which are cyclized to spiroimidazo[1,5-a]imidazole-5-thiones (or selenones) 6.
    Additional Material: 3 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jlac.1993199301199
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  • 9
    Electronic Resource
    Electronic Resource
    Studies on isocyanides and related compounds. - Synthesis and cyclization of N-substituted 1-isocyano-1-cycloalkanecarboxamides (1991)
    Weinheim : Wiley-Blackwell
    Liebigs Annalen 1991 (1991), S. 843-849 
    Details
    ISSN: 0170-2041
    Keywords: Isocyanides ; Ugi four-component condensation (4CC) ; Spiroimidazole-2-thiones ; Spiroimidazole-4-ones ; Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The Ugi four-component condensation between cycloalkanones, isocyanides, and ammonium formate affords N-substituted 1-formylamino-1-cycloalkanecarboxamides 1 which are dehydrated to give the corresponding isocyanides 2. Compounds 2 are cyclized with arylsulfenyl thiocyanates to 1,3-diazaspiro-2-thiones 4 and 5. A series of 1,3-diazaspiro[4,5]dec-1-en-4-ones 7 is prepared by cyclizing 2c-j with butyllithium. The structures of these compounds are confirmed by means of IR, 1H-NMR, and X-ray analysis.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jlac.1991199101145
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  • 10
    Electronic Resource
    Electronic Resource
    CD36 mediates binding of soluble thrombospondin-1 but not cell adhesion and haptotaxis on immobilized thrombospondin-1 (1998)
    New York, NY [u.a.] : Wiley-Blackwell
    Cell Biochemistry and Function 16 (1998), S. 211-221 
    Details
    ISSN: 0263-6484
    Keywords: thrombospondin ; CD36, cell adhesion ; cell migration ; Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: In this study, we examined the binding of soluble TSP1 (and ox-LDL) to CD36-transfected cells and the mechanisms by which immobilized TSP1 mediated attachment and haptotaxis (cell migration towards a substratum-bound ligand) of these transfected cells. CD36 cDNA transfection of NIH 3T3 cells clearly induced a dramatic increase in binding of both soluble [125I]-TSP1 and [125I]-ox-LDL to the surface of CD36-transfected cells, indicating that there was a gain of function with CD36 transfection in NIH 3T3 cells. Despite this gain of function, mock- and CD36-transfected NIH 3T3 cells attached and migrated to a similar extent on immobilized TSP1. An anti-TSP1 oligoclonal antibody inhibited CD36-transfected cell attachment to TSP1 while function blocking anti-CD36 antibodies, alone or in combination with heparin, did not. A series of fusion proteins encompassing cell-recognition domains of TSP1 was then used to delineate mechanisms by which NIH 3T3 cells adhere to TSP1. Although CD36 binds soluble TSP1 through a CSVTCG sequence located within type 1 repeats,18,19 CD36-transfected NIH 3T3 cells did not attach to immobilized type 1 repeats while they did adhere to the N-terminal, type 3 repeats (in an RGD-dependent manner) and the C-terminal domain of TSP1. Conversely, Bowes melanoma cells attached to type 1 repeats and the N- and C-terminal domains of TSP1. However, CD36 cDNA transfection of Bowes cells did not increase cell attachment to type 1 repeats compared to that observed with mock-transfected Bowes cells. Moreover, a function blocking anti-CSVTCG peptide antibody did not inhibit the attachment of mock- and CD36-transfected Bowes cells to type 1 repeats. It is suggested that CD36/TSP1 interaction does not occur upon cell-matrix adhesion and haptotaxis because TSP1 undergoes conformational changes that do not allow the exposure of the CD36 binding site. © 1998 John Wiley & Sons, Ltd.
    Additional Material: 4 Ill.
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