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  • 1
    Electronic Resource
    Electronic Resource
    LDH variants in India (1970)
    Springer
    Human genetics 〈Berlin〉 9 (1970), S. 107-109 
    Details
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary 17 examples of genetically controlled variation of LDH have been encountered in a survey of 1331 Indian blood samples collected in Calcutta and Madras. 15 of the variants (10 in Calcutta and 5 in Madras) were identical and have been given the trivial name ‘Calcutta-1’. The other 2 examples were found in Madras and have been called ‘Madras-1’. ‘Calcutta-1’ is an A-subunit variant, whilst ‘Madras-1’ is a B-subunit variant. The overall frequency of LDH variants in India (1.28 per cent) is among the highest reported for any population in the world.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00696021
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  • 2
    Electronic Resource
    Electronic Resource
    New Genetic Variant of 6-Phosphogluconate Dehydrogenase in Australian Aborigines (1969)
    [s.l.] : Nature Publishing Group
    Nature 221 (1969), S. 278-278 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] In a survey of 6.PGD electrophoretic phenotypes among Australian aborigines we have recently detected a new phenotype. This phenotype is present in many of the aboriginal populations sampled in the Northern Territory of Australia and the trivial name "Elcho" is proposed after the Island locality in ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/221278a0
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  • 3
    Electronic Resource
    Electronic Resource
    Additional electrophoretic variants of 6-phosphogluconate dehydrogenase (1974)
    Springer
    Human genetics 〈Berlin〉 21 (1974), S. 347-354 
    Details
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Description / Table of Contents: Zusammenfassung Es werden 6 neue PGD-Allele beschrieben. 2 davon (PGD Wantoat und PGD Canberra) sind Kontrollproteine, die elektrophoretisch langsam sind. Die 4 übrigen kontrollieren schnelle Variaten. Die Heterozygote PGD A/PGD Wantoat und PGD A/PGD Canberra zeigen einen ähnlichen Abstand der Banden bei Stärkegelelektrophoresis, jedoch sind die relativen Intensitäten der Streifen in beiden Mustern verschieden. Von den 4 schnellen Allelvarianten kontrolliert PGD Kadar ein Genprodukt mit schnellster Mobilität; PGD Caspian wirkt etwas langsamer, und sowohl PGD Bombay als auch PGD Natal zeigen eine ähnliche Wandlungsgeschwindigkeit, obwohl sie unter Behandlung mit 2-Mercaptoethanol verschieden reagieren. Nach Behandlung mit diesem Reagens werden Muster mit PGD Natal wieder normal. Keine der anderen Genprodukte, der PGD-Allele, die hier geprüft werden, werden durch Behandlung mit 2-Mercaptoethanol beeinflußt. PGD Kadar stellte sich in der Kadar-Sippenbevölkerung Südindiens als polymorph heraus. 3 ausgeprägte neue Muster wurden in dieser Bevölkerung entdeckt, nämlich: der Homozygote PGD Kadar/PGD Kadar, der Heterozygote PGD A/PGD Kadar und der Heterozygote PGD C/PGD Kadar.
    Notes: Summary 6 new PGD alleles are described. 2 of these (PGD Wantoat and PGD Canberra) control proteins that are electrophoretically slow: the other 4 control fast variants. The heterozygotes PGD A/PGD Wantoat and PGD A/PGD Canberra give similar band spacing after starch gel electrophoresis, but the relative intensities of the bands in the 2 patterns is different. Of the 4 fast variant alleles PGD Kadar controls a gene product with fastest mobility, PGD Caspian is slightly slower, whilst PGD Bombay and PGD Natal are similar in the mobility of their gene products, but differ in their reaction to treatment with 2-mercaptoethanol. After treatment with this reagent patterns involving PGD Natal revert to normal. None of the other gene products of the PGD alleles tested are affected by treatment with 2-mercaptoethanol. PGD Kadar was found to be polymorphic in the tribal Kadar population of south India. 3 distinctive new patterns were found in this population representing the homozygote PGD Kadar/PGD Kadar, the heterozygote PGD A/PGD Kadar and the heterozygote PGD C/PGD Kadar.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00273373
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  • 4
    Electronic Resource
    Electronic Resource
    Malate dehydrogenase types in the Asian-Pacific area, and a description of new phenotypes (1978)
    Springer
    Human genetics 〈Berlin〉 43 (1978), S. 69-80 
    Details
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary A survey of more than 21 000 haemolysates from blood samples collected in various parts of south and southeast Asia, Australasia and the Western Pacific and examined in this laboratory has revealed several new alleles controlling variants of sMDH; in addition, further information has been provided on the distribution of sMDH3 in New Guinea. Two of the variant alleles, sMDH3 and sMDH6, achieve polymorphic frequency in various populations. sMDH3 is widely distributed in New Guinea, with highest frequencies in the Eastern Highlands. The pattern of its distribution suggests the mutant arose originally in a Papuan-speaking populations. So far, sMDH6 has been detected only in Micronesians from a number of islands in the Carolines. A single example of another new variant, sMDH 5-1, and two examples of a slow variant, sMDH 7-1, were detected in samples from Iran and Singapore, respectively. No examples of mMDH variants were found in a total of 652 placental extracts from Papua New Guinea and Australia.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00396480
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  • 5
    Electronic Resource
    Electronic Resource
    Genetic variants of soluble malate dehydrogenase in new guinea populations (1970)
    Springer
    Human genetics 〈Berlin〉 11 (1970), S. 72-74 
    Details
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary 10 cases of an S-MDH variant have been detected in New Guinea. 3 cases were found among 199 samples from the Fore linguistic group and 6 cases among 9 related members of a family from the Agarabi linguistic group, both groups being located in the Eastern Highlands. 1 case was found in 24 samples from the Sepik district. The new variant has been given the trivial name S-MDH “New Guinea-1”.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00296307
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  • 6
    Electronic Resource
    Electronic Resource
    The distribution of red cell enzyme and serum protein groups in a population of Dani (Pit River, West Irian) (1973)
    Springer
    Human genetics 〈Berlin〉 17 (1973), S. 345-350 
    Details
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Description / Table of Contents: Zusammenfassung Blutproben einer Anzahl Dani-sprechender Personen des Pit River-Gebietes in West-Irian wurden auf genetische Varianten in 14 Erythrocytenenzym- und 5 Serumprotein-Systemen untersucht. 4 der Erythrocytenenzym-Systeme waren polymorph: Saure Phosphatase, 6PGD, Adenosindeaminase und Phospho-glucomutase1. Zwei der Serum-protein-Systeme, Haptoglobin und Transferrin, waren polymorph. In den anderen Systemen wurden 3 MDH “New Guinea-1”-Varianten gefunden, ebenso wie 2 Personen mit Varianten, 1 MS und 1 SS, im Pi-System. Eine ungewöhnliche Variante im PGM2-System ist noch nicht ausreichend bestimmt worden. Alle anderen Systeme waren monomorph.
    Notes: Summary Blood samples from a series of Dani speaking persons from Pit River, West Irian have been studied for genetic variants in 14 red cell enzyme and 5 serum protein systems. Four of the red cell enzyme systems were polymorphic: acid phosphatase, 6 phosphogluconate dehydrogenase, adenosine deaminase and phosphoglucomutase (locus 1). Two of the serum protein systems, haptoglobin and transferrin, were polymorphic. In the other systems three MDH “New Guinea-1” variants were detected and two persons with variants, one MS and one SS, in the protease inhibitor system were detected also. An unusual variant in the PGM (locus 2) system has not yet been adequately identified. All other systems were monomorphic.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00273191
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  • 7
    Electronic Resource
    Electronic Resource
    The distribution of serum protein and enzyme groups among the Batak of Samosir Island (Sumatra, Indonesia) (1973)
    Springer
    Human genetics 〈Berlin〉 17 (1973), S. 351-356 
    Details
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Description / Table of Contents: Zusammenfassung 188 Blutproben des Batak-Stammes von Samosir Island (Sumatra, Indonesien) wurden auf elektrophoretische Varianten des Hämoglobins in 14 Erythrocyten-enzym-und 5 Serumprotein-Systemen untersucht. Die Saure Phosphatase, 6GPD, PGM1 und ADA-Systeme sind polymorph, und eine einzige AK 2-1-Person wurde gefunden. In den Haptoglobin-, Transferrin- und Pi-Systemen treten Polymorphismen auf. Zwei abweichende Allele, Tf Dchi und Tf B, sind im Transferrin-System zu finden, aber die B-Variante ist nicht bestimmt worden. Ebenso wurden 3 Personen mit Ceruloplasmin-Varianten gefunden, doch auch diese Varianten wurden nicht identifiziert. Keine abnormen Hämoglobine wurden gefunden. Alle anderen Systeme wiesen nur normale Phenotypen auf.
    Notes: Summary 188 blood samples from Batak of Samosir Island (Sumatra, Indonesia) have been studied for electrophoretic variants of haemoglobin, 14 red cell enzyme and 5 serum protein systems. The acid phosphatase, 6 PGD, PGM1 and ADA enzyme systems are polymorphic, and a single AK 2-1 person was detected. Polymorphism is present in the haptoglobin, transferrin and protease inhibitor systems. Two variant alleles, Tf Dchi and Tf B are present in the transferrin system, but the B variant has not been identified. Similarly, 3 persons with caeruloplasmin variants were found, but also these variants have not been identified. No abnormal haemoglobins were detected. All other systems revealed the presence of only normal phenotypes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00273192
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  • 8
    Electronic Resource
    Electronic Resource
    Glutamic pyruvic transaminase and esterase D types in the Asian-Pacific area (1976)
    Springer
    Human genetics 〈Berlin〉 35 (1976), S. 91-102 
    Details
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary More than 11000 blood samples have been examined for glutamicpyruvic transaminase (GPT) and almost 9000 for Esterase D (EsD) in the Asian-Pacific area; GPT 3 and GPT 6 were detected in several population groups in New Guinea, Singapore and some Pacific islands. No previously undescribed alleles were found in either system.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00295623
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  • 9
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    LDH variants in India (1970)
    Springer
    Details
    Publication Date: 1970-01-01
    Print ISSN: 0340-6717
    Electronic ISSN: 1432-1203
    Topics: Biology , Medicine
    Published by Springer
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  • 10
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    Malate dehydrogenase types in the Asian-Pacific area, and a description of new phenotypes (1978)
    Springer
    Details
    Publication Date: 1978-01-01
    Print ISSN: 0340-6717
    Electronic ISSN: 1432-1203
    Topics: Biology , Medicine
    Published by Springer
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