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  • 1
    Keywords: Nervous system Surgery. ; Neurology . ; Radiology. ; Neurosurgery. ; Neurology. ; Radiology.
    Description / Table of Contents: Evidence on Mechanical Thrombectomy in Acute Ischemic Stroke -- In Vitro Clot Modeling and Clinical Applications -- Approaches to Mechanical Thrombectomy in Children with Arterial Ischemic Stroke -- ELVO in Urban Areas: Evolution of Stroke Systems of Care -- Surviving Large Vessel Occlusions in Uruguay: Current Challenges and Solutions -- Direct to Angiography—An Emerging Paradigm in Large Vessel Occlusion Stroke: Rationale, Feasibility, and Preliminary Results -- Thrombectomy Techniques: Stent Retriever - Balloon Guide -- Direct Aspiration thrombectomy for acute stroke: Evolution of technique and evidence -- The Stentriever-Mediated Aspiration Thrombectomy (SMAT) Technique -- Transradial Approach for Stroke -- Thrombectomy Techniques: Remote Aspiration -- Endovascular Therapy for Middle Cerebral Artery Occlusions -- Thrombectomy for Basilar Occlusion: Approach and Strategy -- Carotid Terminus Occlusion -- Thrombectomy for Acute Occlusion in Intermediate-Sized Distal Arteries -- The Tandem Occlusion -- Acute Stroke Thrombectomy and Emergent Management of Tandem Cervical Dissections -- Acute Stroke Following Carotid Endarterectomy: Approach and Strategy -- Large vessel occlusion with underlying atherosclerosis: approach and strategy -- Large Vessel Occlusion with Low NIHSS: Approach and Strategy -- Challenges in Thrombectomy: Mega Clots -- Challenges in thrombectomy: Access Problems, Hard Clots, Relapsing Occlusions and Embolizaton to New Territories -- Challenges in Thrombectomy: Impossible Aortic Arches and Tortuous Vessels.
    Abstract: This comprehensive, case-based resource provides the state-of-the-art knowledge that can help readers improve access and optimize delivery of stroke thrombectomy. Improving access to stroke is of particular importance because patients often misinterpret their symptoms or cannot speak for themselves if they have aphasia. More importantly, access needs to be organized because stroke therapies are all extremely time-sensitive. Scalable, choreographed protocols are necessary for emergency medical systems to ‘capture’ stroke patients and automatically transport and triage to time-sensitive treatments. Many of the chapters in the first section on Fundamentals and Systems provide valuable insight in improving access to stroke care. Replete with illustrative case studies and emphasizing that treatment approaches to stroke should not be comprised of a one-size-fits-all approach, this illuminating title provides the complete thought, detail, insight and organization that will help readers meet the needs of stroke patients with large vessel occlusions. 12 Strokes: A Case-based Guide to Acute Ischemic Stroke Management examines the primary technical principles that underlie the current thrombectomy approaches. Instead of continuing the conceptual dichotomy of stent vs. aspiration, many of the chapters look at underlying principles and then discuss ways in which the currently available devices and approaches can best exploit them. The variety, creativity and detail in many of these chapters will help the reader develop a deeper understanding that might assist their ability to successfully take care of their next patient that ‘doesn’t follow the textbook.’ In addition, the anatomic and pathophysiologic classification of the core Twelve Chapters will help readers organize their thinking and approach. This knowledge, particularly because it is organized based on common, challenging syndromes, will arm the reader to quickly recognize patterns and deftly adapt their management approaches to the needs of the patient. An invaluable contribution to the clinical literature, 12 Strokes: A Case-based Guide to Acute Ischemic Stroke Management will be of great interest to not only neurosurgeons and neurologists but other specialists, primary care providers, and trainees as well. .
    Type of Medium: Online Resource
    Pages: XVII, 337 p. 115 illus., 60 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030568573
    DDC: 617.48
    Language: English
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  • 2
    Keywords: Sustainability. ; Climatology. ; Agriculture. ; Human geography. ; Anthropology. ; Sustainability. ; Climate Sciences. ; Agriculture. ; Human Geography. ; Anthropology.
    Description / Table of Contents: Introduction -- Glaciers of Central Ladakh: Distribution, Changes and Relevance in the Indian Trans-Himalaya -- Floods and Debris Flows in Ladakh: Past History and Future Hazards -- Impact of 2010 Leh Cloudburst: a Psychological Perspective -- Traditional Mathematical Theories of Rainfall Prediction through Lotho as Practised in Ladakh -- The Contribution of Czech Researchers to the Botanical Survey of Ladakh -- The Adaptations of High-Altitude Mushrooms in the Cold Desert of Ladakh -- A Brief Description of Sacred Trees (lhachang) -- Environmental Change in Ladakh’s Changthang: a Local, Regional and Global Phenomenon -- Wildlife versus Livestock: Conservation Dilemma of the Pastoralists of Changthang -- Harnessing Traditional Knowledge for Wildlife Conservation in the Ladakh Trans-Himalaya -- Changing Production, Changing Consumption: Food System Transformation in Ladakh -- Eating Habits In and Around Leh Town -- Seeds of Change: A Review of Agricultural Developments in Central Zangskar -- Influences of Tourism, Indian Administration and Army on Community Identity Processes in Padum (Zangskar) -- “We Are Puppets in the Hands of Nature”: Road Construction and the Transformation of People-Environment Relationships in Ladakh -- Trade-Off between Continuity and Change in Leh District: an Emergy Evaluation in Time Series: 1999-2011.
    Abstract: The Trans-Himalayan region of Ladakh has witnessed important changes linked to its geo-strategic importance, the rapid development of means of communication with other parts of India, socio-economic transformation processes and the effects of climate change. The sixteen chapters document these key changes, ranging from melting glaciers and extreme weather events to the exponential increase in infrastructure, tourist and military activities. The book examines the impact these changes are having on the environment and on the socio-economics and identity of Ladakhi communities. The book also attempts to evaluate the likely direction of future changes, identify some of the main environmental challenges faced by Ladakh in the 21st century, and provide perspectives for sustainable development of the high mountain region.
    Type of Medium: Online Resource
    Pages: X, 283 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031424946
    Series Statement: Advances in Asian Human-Environmental Research,
    DDC: 304.2
    Language: English
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  • 3
    Monograph available for loan
    Monograph available for loan
    Berlin : Asher
    Associated volumes
    Call number: MOP 718
    In: Neudrucke von Schriften und Karten über Meteorologie und Erdmagnetismus
    Type of Medium: Monograph available for loan
    Pages: 8, 20 S. : Ill.
    Edition: [Neudr. von 1648]
    Series Statement: Neudrucke von Schriften und Karten über Meteorologie und Erdmagnetismus 2
    Location: MOP - must be ordered
    Branch Library: GFZ Library
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  • 4
    Call number: 2/M 14.0158
    Type of Medium: Monograph available for loan
    Pages: vii, 480 S. : graph. Darst.
    ISBN: 9780262525510
    Classification:
    E.9.
    Location: Reading room
    Branch Library: GFZ Library
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  • 5
  • 6
    Publication Date: 2013-11-15
    Description: Objectives Over the past decade, invasive fungal infections (IFI) have remained an important problem in patients undergoing hematopoietic stem cell transplantation (HSCT). The optimal approach for prophylactic antifungal therapy has yet to be determined. Patients and Methods we conducted a retrospective, bi-institutional comparative clinical study, (Institut Paoli-Calmettes at Marseille France and Humanitas cancer center at Rozzano, Italy), and we compared the efficacy and safety of Micafungin 50mg/day (iv) with those of fluconazole (400mg/day) or itraconazole 200mg/day (iv) as prophylaxis for adult patients with various haematological diseases receiving haplo-identical allogeneic stem cell transplantation (haplo-SCT). Patients received prophylaxis with the beginning of the transplant conditioning regimen until the hospital discharge, or until occurrence of an IFI. We compared the incidence of proven or probable IFI (the primary end point) between the micafungin and fluconazole or itraconazole groups; death from any cause and time to death was secondary end points. Patients were followed for 100 days after haplo-SCT and for 30 days after the last dose of the prophylaxis drug administrated. Results From January 2009 to May 2013, a total of 99 patients were identified; 30 patients received micafungin, and 69 patients received fluconazole or itraconazole. 81 patients (82%) received a non myeloabaltive conditioning regimen (NMA), with Fludarabine, Cyclophosphamide and Total body irradiation (TBI) 2 Gy based , or Fludarabine, Busulfan, and Cyclophosphamide based (3%) or other (9%), while five patients (5%) received a thiotepa-based conditioning regimen. The patients and transplant details are shown in the table 1. Proven or probable invasive fungal infections were reported in 2 patients (7%) in the micafungin group and 8 patients (12%) in the fluconazole or itraconazole group (absolute reduction in the micafungin group, −5%; 95% confidence interval, 0.0565-3.1395, P=0.72). Fewer patients in the micafungin group had invasive aspergillosis (1 [3%] vs. 5 [7%], P=0.6). A total of 4 (13%) patients in the micafungin group and 23 (33%) patients in the fluconazole or itraconazole group received empirical antifungal therapy (P = 0.14). No serious adverse events related to treatment were reported by patients and there was no treatment discontinuation because of drug related adverse event in both groups. Overall Survival and disease free survival were similar among the two groups (P = 0.97). 6 patients (20%) in the micafungin group died within 100 days, as did 10 patients (14%) in the fluconazole or itraconazole group (P = 0.57). Interestingly the transplant related mortality (TRM) at 100 days was 0% in the micafungin group vs 13% in the second group [CI 95% (0-22)] (p=0,06), whereas the relapse or progression rate at 100 days was 27% vs. 8% respectively [CI 95% (14-44)] (p=0,14). Conclusions In patients undergoing to haplo-SCT, antifungal prophylaxis with micafungin is well tolerated and effective to prevent IFI. Furthermore, the incidence of IFI and invasive aspergillosis seems lower even if this did not attend statistical power, probably due to low number of patients. Disclosures: No relevant conflicts of interest to declare.
    Print ISSN: 0006-4971
    Electronic ISSN: 1528-0020
    Topics: Biology , Medicine
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  • 7
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    In:  http://aquaticcommons.org/id/eprint/12800 | 9595 | 2013-12-21 22:56:49 | 12800 | Gulf and Caribbean Fisheries Institute
    Publication Date: 2021-07-05
    Keywords: Fisheries ; GCFI
    Repository Name: AquaDocs
    Type: conference_item
    Format: application/pdf
    Format: application/pdf
    Format: 45-63
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  • 8
    Publication Date: 2019-07-17
    Repository Name: EPIC Alfred Wegener Institut
    Type: Article , peerRev
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  • 9
    Publication Date: 2023-06-16
    Description: The 1888 Ritter Island volcanic sector collapse triggered a regionally damaging tsunami. Historic eyewitness accounts allow the reconstruction of the arrival time, phase and height of the tsunami wave at multiple locations around the coast of New Guinea and New Britain. 3D seismic interpretations and sedimentological analyses indicate that the catastrophic collapse of Ritter Island was preceded by a phase of deep-seated gradual spreading within the volcanic edifice and accompanied by a submarine explosive eruption, as the volcanic conduit was cut beneath sea level. However, the potential impact of the deep-seated deformation and the explosive eruption on tsunami genesis is unclear. For the first time, it is possible to parameterise the different components of the Ritter Island collapse with 3D seismic data, and thereby test their relative contributions to the tsunami. The modelled tsunami arrival times and heights are in good agreement with the historic eyewitness accounts. Our simulations reveal that the tsunami was primarily controlled by the displacement of the water column by the collapsing cone at the subaerial-submarine boundary and that the submerged fraction of the slide mass and its mobility had only a minor effect on tsunami genesis. This indicates that the total slide volume, when incorporating the deep-seated deforming mass, is not directly scalable for the resulting tsunami height. Furthermore, the simulations show that the tsunamigenic impact of the explosive eruption energy during the Ritter Island collapse was only minor. However, this relationship may be different for other volcanogenic tsunami events with smaller slide volumes or larger magnitude eruptions, and should not be neglected in tsunami simulations and hazard assessment.
    Description: Bundesministerium für Bildung und Forschung http://dx.doi.org/10.13039/501100002347
    Keywords: Tsunami simulations ; Volcanogenic tsunami genesis ; Ritter Island ; Volcanic sector collapse
    Language: English
    Type: doc-type:article
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  • 10
    ISSN: 1520-4995
    Source: ACS Legacy Archives
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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