Publication Date:
2015-02-01
Description:
Article Tumour cells disseminated from the primary tumour can remain dormant for years before initiating metastases. Here Sosa et al. show that the orphan nuclear receptor NR2F1 can be induced by bone marrow cues and by epigenetic drugs to promote quiescence and tumour cell dormancy in several cancer types. Nature Communications doi: 10.1038/ncomms7170 Authors: Maria Soledad Sosa, Falguni Parikh, Alexandre Gaspar Maia, Yeriel Estrada, Almudena Bosch, Paloma Bragado, Esther Ekpin, Ajish George, Yang Zheng, Hung-Ming Lam, Colm Morrissey, Chi-Yeh Chung, Eduardo F. Farias, Emily Bernstein, Julio A. Aguirre-Ghiso
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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