Publication Date:
2015-10-28
Description:
Article All forms of diabetes eventually lead to a reduction in insulin-secreting pancreatic β-cells. Here, the authors report aminopyrazine derivatives, which induce proliferation of rodent as well as human β-cells and improve glucose metabolism in a mouse model of type 1 diabetes. Nature Communications doi: 10.1038/ncomms9372 Authors: Weijun Shen, Brandon Taylor, Qihui Jin, Van Nguyen-Tran, Shelly Meeusen, You-Qing Zhang, Anwesh Kamireddy, Austin Swafford, Andrew F. Powers, John Walker, John Lamb, Badry Bursalaya, Michael DiDonato, George Harb, Minhua Qiu, Christophe M. Filippi, Lisa Deaton, Carolina N. Turk, Wilma L. Suarez-Pinzon, Yahu Liu, Xueshi Hao, Tingting Mo, Shanshan Yan, Jing Li, Ann E. Herman, Bernhard J. Hering, Tom Wu, H. Martin Seidel, Peter McNamara, Richard Glynne, Bryan Laffitte
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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