Publication Date:
2014-11-15
Description:
Article M2-polarized macrophages are generally considered anti-inflammatory, but whether polarization markers always reflect functional states remains debatable. Here the authors show that complexed IgG and TLR co-stimulation, observed in infections or rheumatoid arthritis, elicits an inflammatory response in M2 macrophages. Nature Communications doi: 10.1038/ncomms6444 Authors: Lisa T. C. Vogelpoel, Ivo S. Hansen, Theo Rispens, Femke J. M. Muller, Toni M. M. van Capel, Maureen C. Turina, Joost B. Vos, Dominique L. P. Baeten, Martien L. Kapsenberg, Esther C. de Jong, Jeroen den Dunnen
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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