ISSN:
1052-9306
Keywords:
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Phosphates and phosphoramidates related to 2-chloro-4-t-butylphenyl methyl methylphosphoramidate (crufomate) were synthesized to aid in the identification of crufomate metabolites. Deuterium labeling, metastable determinations and precise mass measurements were used to establish fragmentation pathways. Evidence was obtained for the rearrangement of an N-formyl phosphoramidate (the expected result of oxidative metabolism of N-methyl phosphoramidates) to an iminomethyl phosphate.
Additional Material:
1 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/bms.1200030610
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