ISSN:
1573-4986
Keywords:
leukocytes
;
glycosphingolipids
;
polyglycosylceramides
;
lactosaminoglycans
;
blood group antigens
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract Glycolipids of peripheral leukocytes which had been used for the production of interferon were separated into oligoglycosylceramides, polyglycosylceramides and polyglycosylpeptides (erythroglycan). Neutral oligoglycosylceramides comprised glucosylceramide, galactosylceramide, lactosylceramide, lactotriaosylceramide, globotriaosylceramide andneolactotetraosylceramide. Globotetraosylceramide was not detected. Glycolipids which were more complex thanneolactotetraosylceramide belonged exclusively to theneolacto series of compounds and were essentially unbranched at galactopyranosyl residues. The polyglycosylceramide fraction contained a glycolipid with a probable structure Galβ1-4(Fucα1-3) GlcNAcβ1-3Galβ1-4GlcNAcβ1-3 Galβ1-4GlcNAcβ1-3Galβ1-4Glcβ1-1ceramide. Polyglycosylpeptides were found only in trace amounts and were also unbranched at galactopyranosyl residues. All glycoconjugates studies did not contain significant amounts of carbohydrate structures derived from ABH immunodominant groups.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01225111
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