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  • 1
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    Shared human–robot proportional control of a dexterous myoelectric prosthesis (2019)
    Springer Nature
    Details
    Publication Date: 2019
    Electronic ISSN: 2522-5839
    Topics: Computer Science
    Published by Springer Nature
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  • 2
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    Positional cloning of the gene for multiple endocrine neoplasia-type 1 (1997)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1997-04-18
    Description: Multiple endocrine neoplasia-type 1 (MEN1) is an autosomal dominant familial cancer syndrome characterized by tumors in parathyroids, enteropancreatic endocrine tissues, and the anterior pituitary. DNA sequencing from a previously identified minimal interval on chromosome 11q13 identified several candidate genes, one of which contained 12 different frameshift, nonsense, missense, and in-frame deletion mutations in 14 probands from 15 families. The MEN1 gene contains 10 exons and encodes a ubiquitously expressed 2.8-kilobase transcript. The predicted 610-amino acid protein product, termed menin, exhibits no apparent similarities to any previously known proteins. The identification of MEN1 will enable improved understanding of the mechanism of endocrine tumorigenesis and should facilitate early diagnosis.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Chandrasekharappa, S C -- Guru, S C -- Manickam, P -- Olufemi, S E -- Collins, F S -- Emmert-Buck, M R -- Debelenko, L V -- Zhuang, Z -- Lubensky, I A -- Liotta, L A -- Crabtree, J S -- Wang, Y -- Roe, B A -- Weisemann, J -- Boguski, M S -- Agarwal, S K -- Kester, M B -- Kim, Y S -- Heppner, C -- Dong, Q -- Spiegel, A M -- Burns, A L -- Marx, S J -- New York, N.Y. -- Science. 1997 Apr 18;276(5311):404-7.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Laboratory of Gene Transfer, National Human Genome Research Institute (NHGRI), National Institutes of Health (NIH), Bethesda, MD 20892, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/9103196" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Chromosome Mapping ; Chromosomes, Human, Pair 11 ; *Cloning, Molecular ; DNA, Complementary/genetics ; Exons ; Frameshift Mutation ; *Genes, Tumor Suppressor ; Humans ; Molecular Sequence Data ; Multiple Endocrine Neoplasia Type 1/*genetics ; Mutation ; Neoplasm Proteins/chemistry/*genetics ; *Proto-Oncogene Proteins
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 3
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    Realization of flat band with possible nontrivial topology in electronic Kagome lattice (2018)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2018
    Description: 〈p〉The energy dispersion of fermions or bosons vanishes in momentum space if destructive quantum interference occurs in a frustrated Kagome lattice with only nearest-neighbor hopping. A discrete flat band (FB) without any dispersion is consequently formed, promising the emergence of fractional quantum Hall states at high temperatures. Here, we report the experimental realization of an FB with possible nontrivial topology in an electronic Kagome lattice on twisted multilayer silicene. Because of the unique low-buckled two-dimensional structure of silicene, a robust electronic Kagome lattice has been successfully induced by moiré patterns after twisting the silicene multilayers. The electrons are localized in the Kagome lattice because of quantum destructive interference, and thus, their kinetic energy is quenched, which gives rise to an FB peak in the density of states. A robust and pronounced one-dimensional edge state has been revealed at the Kagome edge, which resides at higher energy than the FB. Our observations of the FB and the exotic edge state in electronic Kagome lattice open up the possibility that fractional Chern insulators could be realized in two-dimensional materials.〈/p〉
    Electronic ISSN: 2375-2548
    Topics: Natural Sciences in General
    Published by American Association for the Advancement of Science (AAAS)
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  • 4
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    Realization of flat band with possible nontrivial topology in electronic Kagome lattice (2018)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2018-11-17
    Description: The energy dispersion of fermions or bosons vanishes in momentum space if destructive quantum interference occurs in a frustrated Kagome lattice with only nearest-neighbor hopping. A discrete flat band (FB) without any dispersion is consequently formed, promising the emergence of fractional quantum Hall states at high temperatures. Here, we report the experimental realization of an FB with possible nontrivial topology in an electronic Kagome lattice on twisted multilayer silicene. Because of the unique low-buckled two-dimensional structure of silicene, a robust electronic Kagome lattice has been successfully induced by moiré patterns after twisting the silicene multilayers. The electrons are localized in the Kagome lattice because of quantum destructive interference, and thus, their kinetic energy is quenched, which gives rise to an FB peak in the density of states. A robust and pronounced one-dimensional edge state has been revealed at the Kagome edge, which resides at higher energy than the FB. Our observations of the FB and the exotic edge state in electronic Kagome lattice open up the possibility that fractional Chern insulators could be realized in two-dimensional materials.
    Electronic ISSN: 2375-2548
    Topics: Natural Sciences in General
    Published by American Association for the Advancement of Science (AAAS)
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  • 5
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    Active tactile exploration using a brain-machine-brain interface (2011)
    Nature Publishing Group (NPG)
    Details
    Publication Date: 2011-10-07
    Description: Brain-machine interfaces use neuronal activity recorded from the brain to establish direct communication with external actuators, such as prosthetic arms. It is hoped that brain-machine interfaces can be used to restore the normal sensorimotor functions of the limbs, but so far they have lacked tactile sensation. Here we report the operation of a brain-machine-brain interface (BMBI) that both controls the exploratory reaching movements of an actuator and allows signalling of artificial tactile feedback through intracortical microstimulation (ICMS) of the primary somatosensory cortex. Monkeys performed an active exploration task in which an actuator (a computer cursor or a virtual-reality arm) was moved using a BMBI that derived motor commands from neuronal ensemble activity recorded in the primary motor cortex. ICMS feedback occurred whenever the actuator touched virtual objects. Temporal patterns of ICMS encoded the artificial tactile properties of each object. Neuronal recordings and ICMS epochs were temporally multiplexed to avoid interference. Two monkeys operated this BMBI to search for and distinguish one of three visually identical objects, using the virtual-reality arm to identify the unique artificial texture associated with each. These results suggest that clinical motor neuroprostheses might benefit from the addition of ICMS feedback to generate artificial somatic perceptions associated with mechanical, robotic or even virtual prostheses.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236080/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236080/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉O'Doherty, Joseph E -- Lebedev, Mikhail A -- Ifft, Peter J -- Zhuang, Katie Z -- Shokur, Solaiman -- Bleuler, Hannes -- Nicolelis, Miguel A L -- DP1 MH099903/MH/NIMH NIH HHS/ -- DP1 OD006798/OD/NIH HHS/ -- DP1 OD006798-01/OD/NIH HHS/ -- DP1OD006798/OD/NIH HHS/ -- NS073125/NS/NINDS NIH HHS/ -- R01 NS073125/NS/NINDS NIH HHS/ -- R01 NS073125-01/NS/NINDS NIH HHS/ -- RC1 HD063390/HD/NICHD NIH HHS/ -- RC1 HD063390-01/HD/NICHD NIH HHS/ -- RC1HD063390/HD/NICHD NIH HHS/ -- England -- Nature. 2011 Oct 5;479(7372):228-31. doi: 10.1038/nature10489.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Biomedical Engineering, Duke University, Durham, North Carolina 27708, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/21976021" target="_blank"〉PubMed〈/a〉
    Keywords: Algorithms ; Animals ; Artificial Limbs ; Brain/*physiology ; Feedback ; Macaca mulatta/*physiology ; *Man-Machine Systems ; Psychometrics ; Reward ; Somatosensory Cortex/physiology ; Touch/*physiology ; *User-Computer Interface
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Published by Nature Publishing Group (NPG)
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  • 6
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    Laser capture microdissection (1996)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1996-11-08
    Description: Laser capture microdissection (LCM) under direct microscopic visualization permits rapid one-step procurement of selected human cell populations from a section of complex, heterogeneous tissue. In this technique, a transparent thermoplastic film (ethylene vinyl acetate polymer) is applied to the surface of the tissue section on a standard glass histopathology slide; a carbon dioxide laser pulse then specifically activates the film above the cells of interest. Strong focal adhesion allows selective procurement of the targeted cells. Multiple examples of LCM transfer and tissue analysis, including polymerase chain reaction amplification of DNA and RNA, and enzyme recovery from transferred tissue are demonstrated.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Emmert-Buck, M R -- Bonner, R F -- Smith, P D -- Chuaqui, R F -- Zhuang, Z -- Goldstein, S R -- Weiss, R A -- Liotta, L A -- New York, N.Y. -- Science. 1996 Nov 8;274(5289):998-1001.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Laboratory of Pathology, National Cancer Institute, Room 2A33, Building 10, 9000 Rockville Pike, Bethesda, MD 20892, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/8875945" target="_blank"〉PubMed〈/a〉
    Keywords: Cell Separation/*methods ; DNA/analysis ; Dissection ; Frozen Sections ; *Histological Techniques ; Humans ; *Lasers ; Paraffin Embedding ; Polymerase Chain Reaction ; Polyvinyls ; Precancerous Conditions/pathology ; RNA/analysis ; Tissue Fixation
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 7
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    Generation of large orbital angular momentum from superposed Bessel beams corresponding to resonant geometric modes (2012)
    American Physical Society (APS)
    Details
    Publication Date: 2012-04-21
    Description: Author(s): Y. F. Chen, Y. C. Lin, W. Z. Zhuang, H. C. Liang, K. W. Su, and K. F. Huang We theoretically verify that a coherent superposition of nearly degenerate Bessel beams characterizes the family of resonant geometric modes in circular billiards. With the ray-wave correspondence, we experimentally exploit a large-aperture cylindrical waveguide to generate the resonant geometric mo... [Phys. Rev. A 85, 043833] Published Fri Apr 20, 2012
    Keywords: Quantum optics, physics of lasers, nonlinear optics, classical optics
    Print ISSN: 1050-2947
    Electronic ISSN: 1094-1622
    Topics: Physics
    Published by American Physical Society (APS)
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  • 8
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    Properties of Semi-dry Flue Gas Desulfurization Ash and Used for Phosphorus Removal (2018)
    Institute of Physics (IOP)
    Details
    Publication Date: 2018-05-17
    Description: The composition of Semi-dry Flue Gas Desulfurization ash was as follows: CaSO 3 · 0.5H 2 O and Ca(OH) 2 . Most of the particle size was about 8 µm; particles were irregular and small, while the other part was rough and globular. CaSO 3 strongly oxidized at about 466°C and Ca(OH) 2 decomposed at ∼ 662°C. The maximum amount of phosphorus removal in Semi-dry Flue Gas Desulfurization ash was 79.898 mg/g.
    Print ISSN: 1757-8981
    Electronic ISSN: 1757-899X
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Published by Institute of Physics (IOP)
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  • 9
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    Axl-altered microRNAs regulate tumorigenicity and gefitinib resistance in lung cancer (2014)
    Springer Nature
    Details
    Publication Date: 2014-05-16
    Description: Axl-altered microRNAs regulate tumorigenicity and gefitinib resistance in lung cancer Cell Death and Disease 5, e1227 (May 2014). doi:10.1038/cddis.2014.186 Authors: Y Wang, H Xia, Z Zhuang, L Miao, X Chen & H Cai
    Keywords: AxlmicroRNAnon-small cell lung cancergefitinibepithelial-to-mesenchymal transition
    Electronic ISSN: 2041-4889
    Topics: Biology , Medicine
    Published by Springer Nature
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  • 10
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    Yunnan-III models for evolutionary population synthesis (2013)
    Oxford University Press
    Details
    Publication Date: 2013-01-03
    Description: We build the Yunnan-III evolutionary population synthesis (EPS) models by using the mesa stellar evolution code, BaSeL stellar spectra library and the initial mass functions (IMFs) of Kroupa and Salpeter, and present colours and integrated spectral energy distributions (ISEDs) of solar-metallicity stellar populations (SPs) in the range of 1 Myr to 15 Gyr. The main characteristic of the Yunnan-III EPS models is the usage of a set of self-consistent solar-metallicity stellar evolutionary tracks (the masses of stars are from 0.1 to 100 M ). This set of tracks is obtained by using the state-of-the-art mesa code. mesa code can evolve stellar models through thermally pulsing asymptotic giant branch (TP-AGB) phase for low- and intermediate-mass stars. By comparisons, we confirm that the inclusion of TP-AGB stars makes the V – K , V  – J and V  – R colours of SPs redder and the infrared flux larger at ages log( t /yr)  7.6 [the differences reach the maximum at log( t /yr) ~ 8.6, ~0.5–0.2 mag for colours, approximately two times for K -band flux]. We also find that the colour-evolution trends of Model with-TPAGB at intermediate and large ages are similar to those from the starburst99 code, which employs the Padova-AGB stellar library, BaSeL spectral library and the Kroupa IMF. At last, we compare the colours with the other EPS models comprising TP-AGB stars (such as CB07, M05, V10 and POPSTAR), and find that the B  – V colour agrees with each other but the V-K colour shows a larger discrepancy among these EPS models [~1 mag when 8 log( t /yr)  9]. The stellar evolutionary tracks, isochrones, colours and ISEDs can be obtained on request from the first author or from our website ( http://www1.ynao.ac.cn/~zhangfh/ ). Using the isochrones, you can build your EPS models. Now the format of stellar evolutionary tracks is the same as that in the starburst99 code; you can put them into the starburst99 code and get the SP’s results. Moreover, the colours involving other passbands or on other systems (e.g. HST F 439 W  – F 555 W colour on AB system) can also be obtained on request.
    Print ISSN: 0035-8711
    Electronic ISSN: 1365-2966
    Topics: Physics
    Published by Oxford University Press
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