ISSN:
1013-9826
Source:
Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
Topics:
Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
Notes:
Characterization of an hyaluronic acid (HA)-poly(ethylene oxide) (PEO) hydrogel wasperformed by changing the number of side arms in a PEO molecule. Verification of graftingchemistry and mechanical strength, as well as swelling behaviors and surface morphologies of theHA-PEO hydrogels were analyzed by employing different x-linking molecular weights (MW) ofPEO ranging from 1.7 to 5.0 kDa at a fixed low MW HA in the hydrogel network. Methacrylationto the HA successfully obtained via Michael type reaction between the methacrylate arm groups inHA and the thiol end groups in PEO was observed by XPS. Hydrogel formation was markedlydependent upon the numbers of thiol groups in the PEO molecule. Furthermore the lower MWPEO-based HA hydrogel demonstrated stronger mechanical properties but lower water absorptionand the smaller pore sizes on its surface and cross section
Type of Medium:
Electronic Resource
URL:
http://www.tib-hannover.de/fulltexts/2011/0528/01/54/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.342-343.749.pdf
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