ISSN:
1420-9071
Keywords:
Marine sponge
;
halogenated steroid
;
antitumor substance
;
Xestospongia
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract A novel chlorinated steroid, aragusterol C, was isolated from an Okinawan marine sponge of the genusXestospongia. The compound strongly inhibited the proliferation of KB cells in vitro, and also showed potent in vivo antitumor activity against L1210 cells in mice. The complete structure of aragusterol C was determined by spectroscopic analysis and X-ray crystallographic analysis.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01984951
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