ISSN:
1617-4623
Keywords:
Key wordsnrd
;
Ribonucleoside diphosphate reductase
;
IciA
;
DnaA
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Abstract The E. coli nrd operon contains the genes encoding the two subunits of ribonucleoside diphosphate reductase. We found that the IciA protein binds specifically to the AT-rich upstream region of nrd promoter. In vivo overexpression of IciA increases the expression of nrd gene by four- to five-fold, suggesting that IciA functions as a transcriptional activator for the nrd gene.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/s004380050854
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