Publication Date:
2018-05-24
Description:
Silicon-oriented regio- and enantioselective rhodium-catalyzed hydroformylation Silicon-oriented regio- and enantioselective rhodium-catalyzed hydroformylation, Published online: 23 May 2018; doi:10.1038/s41467-018-04277-7 Hydroformylation of 1,2-disubstituted alkenes usually occurs at the α position of the directing heteroatom. Here, the authors report the asymmetric rhodium-catalyzed hydroformylation of 1,2-disubstituted alkenylsilanes with excellent regioselectivity at the β position (relative to the silicon heteroatom) and enantioselectivity.
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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