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  • 1
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    Experimental Study on Time Features of Particle Motion in Rotating Drums (2011)
    Wiley
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    Publication Date: 2011-06-01
    Description: Rotating drums are widely used in pharmaceutical industry to coat tablets. The motion of the tablet particle is one of the most important factors affecting coating uniformity. The purpose of the research is to experimentally investigate two important time variables for the coating process, residence time and turnover time, and their dependence on operating parameters (rotation speed and filling degree of the drum). The average residence time was found to decrease with increasing rotation speed and filling degree. The average turnover time was observed to increase approximately linearly with the inverse of the drum speed, but was found to be independent of the filling degree. A dimensionless time variable, the fractional residence time, i.e., the residence time divided by the turnover time, was introduced. Analysis showed that the fractional residence time could be a good indicator of coating uniformity. Results of the present work provide useful information for theoretical modeling which may ultimately serve as a tool for coating optimization. Rotating drums are widely used in pharmaceutical industry to coat tablets. The time features of the particle motion in the drum exert great influence on the coating performance. In the present work, effects of drum operating parameters on particle residence time and turnover time were investigated in a quasi-2D rotating drum using the image-processing technique.
    Print ISSN: 0930-7516
    Electronic ISSN: 1521-4125
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Published by Wiley
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  • 2
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    The production mechanisms of OH radicals in a pulsed direct current plasma jet (2014)
    American Institute of Physics (AIP)
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    Publication Date: 2014-09-30
    Description: The production mechanism of OH radicals in a pulsed DC plasma jet is studied by a two-dimensional (2-D) plasma jet model and a one-dimensional (1-D) discharge model. For the plasma jet in the open air, electron-impact dissociation of H 2 O, electron neutralization of H 2 O + , as well as dissociation of H 2 O by O(1D) are found to be the main reactions to generate the OH species. The contribution of the dissociation of H 2 O by electron is more than the others. The additions of N 2 , O 2 , air, and H 2 O into the working gas increase the OH density outside the tube slightly, which is attributed to more electrons produced by Penning ionization. On the other hand, the additions of O 2 and H 2 O into the working gas increase the OH density inside the tube substantially, which is attributed to the increased O (1D) and H 2 O concentration, respectively. The gas flow will transport high density OH out of the tube during pulse off period. It is also shown that the plasma chemistry and reactivity can be effectively controlled by the pulse numbers. These results are supported by the laser induced fluorescence measurements and are relevant to several applications of atmospheric-pressure plasmas in health care, medicine, and materials processing.
    Print ISSN: 1070-664X
    Electronic ISSN: 1089-7674
    Topics: Physics
    Published by American Institute of Physics (AIP)
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  • 3
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    U-Pb ages of detrital zircons from deep-water Well LS33A at Lingnan Low Uplift of the Qiongdongnan Basin and their geological significances (2017)
    Institute of Physics (IOP)
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    Publication Date: 2017-12-19
    Description: U-Pb ages of detrital zircons from Well LS33A at Lingnan Low Uplift of the Qiongdongnan Basin (QDNB) are measured with LA-ICP-MS technique. Th/U ratios of detrital zircons mostly with oscillatory zoning are higher than 0.1, indicating a magmatic origin. Zircon U-Pb data of the Yacheng Formation yield an age range from 95.8 to 387.9 Ma, with two major clusters of 95-106 Ma and 214-237 Ma, representing Yanshanian and Indosinian, respectively. U-Pb age range of the Yinggehai-Ledong Formations varies widely from 87 to 2 490 Ma, exhibiting four remarkable age peaks of 88 Ma, 146 Ma, 208 Ma and 386 Ma on age spectrum. The variation in zircon age assemblage reveals that in provenance. Based on synthesizing seismic data, heavy mineral assemblages, geochemical data and zircon U-Pb ages, the main conclusions are as follows. There existed frequent fault-block activities in study area during the Yacheng deposition of Early Oligocene, which controlled the wedge-shaped disorderly fillings, an...
    Print ISSN: 1755-1307
    Electronic ISSN: 1755-1315
    Topics: Geography , Geosciences , Physics
    Published by Institute of Physics (IOP)
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  • 4
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    Measurement and correlation of the solubility of gossypol acetic acid and gossypol acetic acid of optical activity in different solvents (2018)
    Institute of Physics (IOP)
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    Publication Date: 2018-02-03
    Description: The equilibrium method was used to measure the solubility of gossypol acetic acid and gossypol acetic acid of optical activity in isopropyl alcohol, ethanol, acetic acid and ethyl acetate at temperature from 288.15 to 315.15. The Empirical equation and the Apelblat equation model were adopted to correlate the experimental data. For gossypol acetic acid, the root-mean-square deviations (RMSD) were observed in the range of 0.023-4.979 and 0.0112-0.614 for the Empirical equation and the Apelblat equation, respectively. For gossypol acetic acid of optical activity, the RMSD were observed in the range of 0.021-2.211 and 0.021-2.243 for the Empirical equation and the Apelblat equation, individually. And the maximum relative average deviation was 7.5%. Both equations offered an accurate mathematical expression of the experimental results. The calculated solubility showed a good relationship with the experimental solubility for most of solvents. This study provided valuable datas not on...
    Print ISSN: 1757-8981
    Electronic ISSN: 1757-899X
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Published by Institute of Physics (IOP)
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  • 5
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    Effect of Zn on the adsorption and desorption of Cry1Ab toxin from Bacillus thuringiensis on clay minerals (2013)
    Mineralogical Society of Great Britain and Ireland
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    Publication Date: 2013-10-02
    Description: The influence of Zn on the adsorption and desorption of Cry1Ab toxin from Bacillus thuringiensis (Bt) on palygorskite and montmorillonite was studied. The adsorption of the toxin gradually increased with increasing Zn concentration from 0 to 1.0 mmol L –1 , and then decreased with further increase in Zn concentration. The adsorption isotherms of the toxin in the absence and presence of Zn were well described by the Langmuir equation ( R 2 〉 0.9810–0.9991). The separation factor ( R L ) decreased with increase of Zn concentration, suggesting that the irreversibility of the adsorption increases. The XRD results showed that the treatment by Tris buffer or Zn(NO 3 ) 2 solution caused an expansion of the interlayer space of montmorillonite but did not affect palygorskite. The IR spectra suggest that Zn was likely to be combined with amino groups on the surface of the toxin. The presence of Zn during the adsorption of the toxin decreased desorption, suggesting that the residual risk of toxin would be exacerbated if soil is polluted by zinc.
    Print ISSN: 0009-8558
    Electronic ISSN: 1471-8030
    Topics: Geosciences
    Published by Mineralogical Society of Great Britain and Ireland
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  • 6
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    RGD-modifided oncolytic adenovirus exhibited potent cytotoxic effect on CAR-negative bladder cancer-initiating cells (2015)
    Springer Nature
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    Publication Date: 2015-05-15
    Description: RGD-modifided oncolytic adenovirus exhibited potent cytotoxic effect on CAR-negative bladder cancer-initiating cells Cell Death and Disease 6, e1760 (May 2015). doi:10.1038/cddis.2015.128 Authors: Y Yang, H Xu, J Shen, Y Yang, S Wu, J Xiao, Y Xu, X-Y Liu & L Chu
    Electronic ISSN: 2041-4889
    Topics: Biology , Medicine
    Published by Springer Nature
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  • 7
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    Ab initio modeling of zincblende AlN layer in Al-AlN-TiN multilayers (2016)
    American Institute of Physics (AIP)
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    Publication Date: 2016-06-14
    Description: An unusual growth mechanism of metastable zincblende AlN thin film by diffusion of nitrogen atoms into Al lattice is established. Using first-principles density functional theory, we studied the possibility of thermodynamic stability of AlN as a zincblende phase due to epitaxial strains and interface effect, which fails to explain the formation of zincblende AlN. We then compared the formation energetics of rocksalt and zincblende AlN in fcc Al through direct diffusion of nitrogen atoms to Al octahedral and tetrahedral interstitials. The formation of a zincblende AlN thin film is determined to be a kinetically driven process, not a thermodynamically driven process.
    Print ISSN: 0021-8979
    Electronic ISSN: 1089-7550
    Topics: Physics
    Published by American Institute of Physics (AIP)
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  • 8
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    The effect of working gas impurities on plasma jets (2015)
    American Institute of Physics (AIP)
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    Publication Date: 2015-04-23
    Description: Air intrusion reduced the purity of working gas inside the tube for plasma jet, and thereby, affected the discharge dynamics. In this paper, the effect of using working gas with different purity level (helium purity 99.99999%, 99.99%, 99.9%, and 99%) on photoionization and the chemical reactivity of plasma jet were studied using a 2 dimensional plasma jet model. Photoionization of air species acted as a source of pre-ionization in front of the ionization region, which facilitated the transition from localized discharge to streamers inside the tube. The density of reactive species inside the tube was found to increase with the concentration of working gas impurities. For the highest purity helium (99.99999%), despite a low photoionization rate and the distance between the photoionization region and ionization region inside the tube, by increasing the applied voltage and decreasing the distance between the electrode and nozzle, plasma jets were formed
    Print ISSN: 1070-664X
    Electronic ISSN: 1089-7674
    Topics: Physics
    Published by American Institute of Physics (AIP)
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  • 9
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    Mechanism for recombination of radiation-induced point defects at interphase boundaries (2012)
    American Physical Society (APS)
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    Publication Date: 2012-01-14
    Description: Author(s): X.-Y. Liu, B. P. Uberuaga, M. J. Demkowicz, T. C. Germann, A. Misra, and M. Nastasi Interfaces play a critical role in the extraordinary resistance to irradiation damage in nanostructured materials. Atomistic simulations are performed to examine defect production and recovery at incoherent interphase boundaries with different atomic structures. The interstitials produced during cas... [Phys. Rev. B 85, 012103] Published Fri Jan 13, 2012
    Keywords: Structure, structural phase transitions, mechanical properties, defects
    Print ISSN: 1098-0121
    Electronic ISSN: 1095-3795
    Topics: Physics
    Published by American Physical Society (APS)
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  • 10
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    Meson cloud contributions to baryon axial form factors (2015)
    American Physical Society (APS)
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    Publication Date: 2015-02-25
    Description: Author(s): X. Y. Liu, K. Khosonthongkee, A. Limphirat, P. Suebka, and Y. Yan The axial form factor as well as the axial charges and radii of octet N, Σ, and Ξ baryons are studied in the perturbative chiral quark model with the quark wave functions predetermined by fitting the theoretical results of the proton charge form factor to experimental data. The theoretical results a... [Phys. Rev. D 91, 034022] Published Tue Feb 24, 2015
    Keywords: Strong Interactions
    Print ISSN: 0556-2821
    Electronic ISSN: 1089-4918
    Topics: Physics
    Published by American Physical Society (APS)
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