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  • 1
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    Loss-of-Function Myeloperoxidase Mutations Are Associated with Increased Neutrophil Counts and Pustular Skin Disease (2020)
    Cell Press
    Details
    Publication Date: 2020-09-01
    Print ISSN: 0002-9297
    Electronic ISSN: 1537-6605
    Topics: Biology , Medicine
    Published by Cell Press
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    PAPER CURRENT
  • 2
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    Loss-of-function myeloperoxidase mutations are associated with increased neutrophil counts and pustular skin disease (2021)
    Cell Press
    Details
    Publication Date: 2021-04-01
    Print ISSN: 0002-9297
    Electronic ISSN: 1537-6605
    Topics: Biology , Medicine
    Published by Cell Press
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    PAPER CURRENT
  • 3
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    (Table 1) Ice thickness of new subglacial lakes identified in the ICECAP RES data and of previously known subglacial lakes (2012)
    PANGAEA
    In:  Supplement to: Wright, Andrew P; Young, Duncan A; Roberts, Jason L; Schroeder, Dustin M; Bamber, Jonathan L; Dowdeswell, Julian A; Young, Neal W; Le Brocq, Anne M; Warner, Roland C; Payne, Antony J; Blankenship, Donald D; van Ommen, Tas D; Siegert, Martin J (2012): Evidence of a hydrological connection between the ice divide and ice sheet margin in the Aurora Subglacial Basin, East Antarctica. Journal of Geophysical Research, 117(F1), F01033, https://doi.org/10.1029/2011JF002066
    Details
    Publication Date: 2024-03-23
    Description: Subglacial hydrology in East Antarctica is poorly understood, yet may be critical to the manner in which ice flows. Data from a new regional airborne geophysical survey (ICECAP) have transformed our understanding of the topography and glaciology associated with the 287,000 km**2 Aurora Subglacial Basin in East Antarctica. Using these data, in conjunction with numerical ice sheet modeling, we present a suite of analyses that demonstrate the potential of the 1000 km-long basin as a route for subglacial water drainage from the ice sheet interior to the ice sheet margin. We present results from our analysis of basal topography, bed roughness and radar power reflectance and from our modeling of ice sheet flow and basal ice temperatures. Although no clear-cut subglacial lakes are found within the Aurora Basin itself, dozens of lake-like reflectors are observed that, in conjunction with other results reported here, support the hypothesis that the basin acts as a pathway allowing discharge from subglacial lakes near the Dome C ice divide to reach the coast via the Totten Glacier.
    Keywords: Antarctica; Comment; Event label; Ice thickness; Identification; International Polar Year (2007-2008); IPY; Lake_Aurora; Lake_Concordia; Lake_L1; Latitude of event; Longitude of event; R03Wa_1; R04Ea_9; R05Ea_4; R05Ea_5; R06Wa_4; R07Ea_9; R07Ta_1; R08Wa_0.1; R08Wa_0.2; R13Ea_8; R15Ea_4; Record length; SPRI-28/63; SPRI-33; SPRI-36; SPRI-37; Totten_2
    Type: Dataset
    Format: text/tab-separated-values, 76 data points
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    DATA PANGAEA
  • 4
    Electronic Resource
    Electronic Resource
    Kelvin-Helmholtz driven modes of the magnetosphere (1999)
    [S.l.] : American Institute of Physics (AIP)
    Physics of Plasmas 6 (1999), S. 4070-4087 
    Details
    ISSN: 1089-7674
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Ultralow frequency (ULF) waves in the magnetosphere are thought to be driven by disturbances of the magnetopause caused by the flow in the magnetosheath. In this paper a model showing how the trapping and excitation of these modes depends upon the shear flow and propagation angle is presented. The ideal magnetohydrodynamics (MHD) equations are used and the perturbations are assumed to be linear. A bounded, uniform magnetospheric cavity, with a finite plasma beta, separated by a vortex sheet from a semi-infinite, field-free, flowing magnetosheath is considered. It is shown that the bounded model allows the trapping and excitation of both fast and slow cavity modes, and that unstable surface modes may also exist. Slow surface modes are unstable only for a small interval of flow speed, becoming fast surface modes for higher flows. Slow cavity modes have small growth rates and are unlikely to be significant observationally. It is shown that fast modes propagating quasiparallel to the flow may be excited for realistic flow speeds, but that for nonparallel modes, much higher flows are required. Finally, an exact method for predicting the onset of instability for fast modes is derived and is shown to occur at the coalescence of modes of opposite energy. © 1999 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.873669
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  • 5
    Electronic Resource
    Electronic Resource
    Trapping and excitation of modes in the magnetotail (2000)
    [S.l.] : American Institute of Physics (AIP)
    Physics of Plasmas 7 (2000), S. 1572-1581 
    Details
    ISSN: 1089-7674
    Source: AIP Digital Archive
    Topics: Physics
    Notes: A slab model of the magnetotail lobes is studied, and the trapping and excitation of fast magnetoacoustic modes is considered. The tail lobe is taken to be uniform with the magnetic-field stretching parallel to the flow in the magnetosheath. The modes are assumed to be trapped between free magnetopause boundaries. The ideal magnetohydrodynamic (MHD) equations are used to study the effects of linear perturbations to this equilibrium state. It is found that the plasma parameters in this region mean that fast magnetoacoustic waves are unlikely to be Kelvin–Helmholtz (KH) unstable for realistic flow speeds, and in fact these modes are likely to be leaky, losing energy across the magnetopause boundary. However, the decay rates of modes propagating both with and against the magnetosheath flow are found to be small for reasonable plasma parameters and this boundary may be reasonably assumed to be reflecting for the purposes of wave guide theory. Slow modes are found to have very small growth rates and since in the magnetotail lobes the plasma beta is very low, they are not expected to be important. © 2000 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.873977
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  • 6
    Electronic Resource
    Electronic Resource
    Analytical treatment of Alfvén resonances and singularities in nonuniform magnetoplasmas (1994)
    [S.l.] : American Institute of Physics (AIP)
    Physics of Plasmas 1 (1994), S. 691-705 
    Details
    ISSN: 1089-7674
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The linear resonant excitation of Alfvén waves in a cold plasma permeated by a nonuniform magnetic field is considered. The equilibrium magnetic field is irrotational and possesses an invariant coordinate perpendicular to the direction of the field. By solving for the coefficients in a Generalized Frobenius Series the regular and singular solutions may be generated. The singular solution is logarithmic and produces a net absorption of energy at the resonant field line. The efficiency of coupling between the fast mode and the resonant Alfvén mode is determined by the following overlap integral along the resonant field line, ∫(ξβrbγ0/hβ)dl; ξβr is the resonant eigenfunction, bγ0 is the compressional/parallel magnetic field perturbation, and hβ is proportional to the separation of background lines of force in the invariant direction. The amplitude of the singular solution is proportional to this integral, while the rate of energy absorption at the resonance is proportional to its square. It is also shown how the analytical solution at the resonance may be used to avoid problems encountered in numerical solutions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.870815
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  • 7
    Electronic Resource
    Electronic Resource
    Site-selective excitation and polarized absorption spectra of Nd3+ in Sr5(PO4)3F and Ca5(PO4)3F (1996)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 79 (1996), S. 1746-1758 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Polarized absorption and fluorescence spectra were analyzed to establish individual energy (Stark) levels of Nd3+ ions in host crystals of Sr5(PO4)3F (SFAP) and Ca5(PO4)3F (FAP). Site-selective excitation and fluorescence facilitated differentiation between Nd3+ ions in emitting sites associated with 1.06 μm stimulated emission, and nonemitting Nd3+ ions in other sites. Measurements were made on samples containing different concentrations of Nd3+ at 4 K and higher temperatures. Substitution of Nd3+ for Sr2+ or Ca2+ was accompanied by passive charge compensation during crystal growth. Crystal-field splitting calculations were performed according to site for Stark levels of Nd3+ ions identified spectroscopically. We obtained a final set of crystal-field parameters Bnm for Nd3+ ions in fluorescing sites with a rms. deviation of 7 cm−1 (52 levels in Nd:SFAP) and 8 cm−1 (59 levels in Nd:FAP). For one of the nonemitting sites in Nd:FAP we obtained a final set of Bnm parameters which gave a rms deviation of 6 cm−1 between 46 experimental and calculated levels. © 1996 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.360964
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  • 8
    Electronic Resource
    Electronic Resource
    Site-selective spectroscopy and determination of energy levels in Eu3+-doped strontium fluorophosphate (1995)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 78 (1995), S. 2456-2467 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Absorbance and site-selective fluorescence studies of Eu3+:Sr5(PO4)3F (Eu:SFAP) provide a nearly complete characterization of the Eu3+ energy levels. These results are compared with calculated energies generated by lattice-sum analysis. Eu3+ is found to occupy one site predominantly, but numerous minority sites are also evident; polarization studies of absorption and fluorescence lines provide evidence for the principle site having Cs symmetry. Vibronic transitions occur in spectra as well. Interpretation of the lattice location and charge compensation mechanism for the principal site is discussed in the context of obstacles arising from spectral interpretation, high crystal fields in SFAP, low site symmetry, low J-numbers in Eu3+ energy manifolds, and lattice covalency. Eu2+ emission upon ultraviolet excitation is also demonstrated; valleys in the emission profile are attributed to intracrystal absorption by Eu3+. © 1995 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.360099
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  • 9
    Electronic Resource
    Electronic Resource
    DNA SEGREGATION IN BACTERIA (2000)
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Microbiology 54 (2000), S. 681-708 
    Details
    ISSN: 0066-4227
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Biology
    Notes: Abstract Segregation of DNA in bacterial cells is an efficient process that assures that every daughter cell receives a copy of genomic and plasmid DNA. In this review, we focus primarily on observations in recent years, including the visualization of DNA and proteins at the subcellular level, that have begun to define the events that separate DNA molecules. Unlike the process of chromosome segregation in higher cells, segregation of the bacterial chromosome is a continuous process in which chromosomes are separated as they are replicated. Essential to separation is the initial movement of sister origins to opposite ends of the cell. Subsequent replication and controlled condensation of DNA are the driving forces that move sister chromosomes toward their respective origins, which establishes the polarity required for segregation. Final steps in the resolution and separation of sister chromosomes occur at the replication terminus, which is localized at the cell center. In contrast to the chromosome, segregation of low-copy plasmids, such as Escherichia coli F, P1, and R1, is by mechanisms that resemble those used in eukaryotic cells. Each plasmid has a centromere-like site to which plasmid-specified partition proteins bind to promote segregation. Replication of plasmid DNA, which occurs at the cell center, is followed by rapid partition protein-mediated separation of sister plasmids, which become localized at distinct sites on either side of the division plane. The fundamental similarity between chromosome and plasmid segregation-placement of DNA to specific cell sites-implies an underlying cellular architecture to which both DNA and proteins refer.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1146/annurev.micro.54.1.681
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  • 10
    Electronic Resource
    Electronic Resource
    A study of O2(a 1Δg) with photoelectron spectroscopy using synchrotron radiation (1998)
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 109 (1998), S. 2737-2747 
    Details
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: The atmospherically important species O2(a 1Δg) has been studied by photoelectron spectroscopy using vacuum ultraviolet radiation from a synchrotron as the photon source. Constant-ionic-state (CIS) spectra, recorded for vibrational levels of O2+(X 2Πg) v+=0,1,2,3 accessed from O2(a 1Δg) v″=0, exhibit intense signals in the photon energy region 14.0–15.5 eV which are shown to arise from autoionization from a Rydberg state with an O2+(C 2Φu) core. On the basis of the results obtained and earlier evidence derived from vacuum ultraviolet absorption spectroscopy, this state is assigned as a (C 2Φu,3sσg) 1Φu Rydberg state. Photoelectron spectra recorded for O2(a 1Δg) at positions of strong resonances have allowed extended vibrational structure to be obtained in the first photoelectron band. The relative vibrational component intensities in the resonant photoelectron spectra are in good agreement with computed relative intensities obtained via Franck–Condon calculations, confirming the vibrational numbering of the resonances in the 1Φu state. Competition between autoionization and predissociation in the 1Φu Rydberg state is discussed on the basis of the results obtained. Weaker structure is observed in CIS spectra recorded in the photon energy regions 12.5–13.5 and 15.0–20.0 eV. Suggestions are made for the nature of the highly excited states of O2 associated with this structure, based on available ionization energies and spectroscopic constants of known ionic states accessible from O2(a 1Δg). For example, two broad bands centered at (approximate)16.4 and (approximate)17.75 eV are assigned to excitation to Rydberg states arising from the configurations (D 2Δg,3pπu) and (D 2Δg,4pπu), respectively. © 1998 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.476872
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