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  • 1
    Keywords: Pharmaceutical chemistry. ; Pharmacology. ; Clinical biochemistry. ; Pharmaceutics. ; Pharmacology. ; Medical Biochemistry.
    Description / Table of Contents: Route-Specific Challenges in the Delivery of Poorly Water-Soluble Drugs -- Optimizing the Formulation of Poorly Water-Soluble Drugs -- Solid-State Techniques for Improving Solubility -- Mechanical Particle-Size Reduction Techniques -- Co-solvent and Complexation Systems -- Injectable Formulations of Poorly Water-Soluble Drugs -- Lipid-Based Formulations -- Structured Development Approach for Amorphous Systems -- Melt Extrusion -- Spray-Drying Technology -- Pharmaceutical Cryogenic Technologies -- Precipitation Technologies for Nanoparticle Production -- Emerging Technologies to Increase the Bioavailability of Poorly Water-Soluble Drugs -- Scientific and Regulatory Considerations for Development and Commercialization of Poorly Water-Soluble Drugs.
    Abstract: The objective of this third edition is to consolidate within a single text the most current knowledge, practical methods, and regulatory considerations pertaining to formulations development with poorly water-soluble molecules. A pharmaceutical scientist’s approach toward solubility enhancement of a poorly water-soluble molecule typically includes detailed characterization of the compound’s physiochemical properties, solid-state modifications, advanced formulation design, non-conventional process technologies, advanced analytical characterization, and specialized product performance analysis techniques. The scientist must also be aware of the unique regulatory considerations pertaining to the non-conventional approaches often utilized for poorly water-soluble drugs. One faced with the challenge of developing a drug product from a poorly soluble compound must possess at a minimum a working knowledge of each of the above mentioned facets and detailed knowledge of most. In light of the magnitude of the growing solubility problem to drug development, this is a significant burden especially when considering that knowledge in most of these areas is relatively new and continues to develop. Highlights the most recent advancements reported in the literature on technologies to improve the dissolution and bioavailability of poorly water soluble drugs Provides a comprehensive discussion of new technologies developed and recently over 40% updated new content Essential read for scientists and researchers in pharmaceutical, chemical, and agricultural industries since over 80% of newly discovered drugs are poorly water soluble.
    Type of Medium: Online Resource
    Pages: XII, 693 p. 280 illus., 138 illus. in color. , online resource.
    Edition: 3rd ed. 2022.
    ISBN: 9783030887193
    Series Statement: AAPS Advances in the Pharmaceutical Sciences Series, 50
    DDC: 615.19
    Language: English
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  • 2
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Environmental sciences Social aspects. ; Human geography. ; Cultural geography. ; Cultural property. ; Sociology, Urban. ; Environmental Social Sciences. ; Social and Cultural Geography. ; Cultural Heritage. ; Urban Sociology.
    Description / Table of Contents: Chapter 01 Rural Sustainability: challenges and opportunities -- Chapter 02 Case study: Rural revitalization in Hong Kong -- Chapter 03 Rural Sustainability: six core dimensions -- Chapter 04 Conclusion and the future of rural communities.
    Abstract: This book highlights the challenges and opportunities of (re)constructing a sustainable rural community on the outskirts of the urban community. Based on knowledge and experience accumulated through implementing a rural revitalisation project in Hong Kong since 2013, the book provides an in-depth analysis of a case study along with related concepts from the literature. In particular, the concept of rural resilience is broken down and used to examine how communities at the urban-rural interface can leverage their position and connections to (re)create vibrant sustainable communities. The revitalisation project was showcased in the databases of the United Nations Development Programme (UNDP)’s Equator Initiative and the International Partnership for the Satoyama Initiative (IPSI) as well as achieving Special Recognition for Sustainable Development in the UNESCO Asia-Pacific Awards for Cultural Heritage Conservation in 2020. This book teases out the key issues in the process of revitalising a rural community in the peri-urban context and examines the complexities embedded in each issue and how they can be addressed in the quest for rural sustainability.
    Type of Medium: Online Resource
    Pages: IX, 94 p. 5 illus., 3 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811658242
    Series Statement: SpringerBriefs on Case Studies of Sustainable Development,
    DDC: 304.2
    Language: English
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  • 3
    Keywords: Earth sciences. ; Geography. ; Sustainability. ; Renewable energy sources. ; Environmental management. ; Schools of economics. ; Economic policy. ; Earth and Environmental Sciences. ; Sustainability. ; Renewable Energy. ; Environmental Management. ; Heterodox Economics. ; Economic Policy.
    Description / Table of Contents: Introduction by William Rees -- Ch 1: The great acceleration, planetary boundaries and the Anthropocene, Will Steffen, Ch 2: Assessing natural environments: a summary, David Lindenmayer & Chris Dickman -- Ch 3: Human health and the natural environment, Colin D. Butler -- Ch 4:UN Sustainability Goals, Kerryn Higgs -- Ch. 5: The evolution of neoliberalism, John Quiggin -- Ch 6: Population growth, Ian Lowe -- Ch 7: Evaluation ‘The Limits to Growth’ 50 Years On, Kerryn Higgs -- Ch 8: The role of the fossil fuel industry, Ian Dunlop -- Ch 9: Economic failures of the IPCC process, Steve Keen -- Ch 10: Introduction to ecological economics, Philip Lawn & Stephen Williams -- Ch 11: Energy systems for sustainable prosperity, Mark Diesendorf -- Ch 12: Climate litigation and human rights, Michael Kirby & Sean Ryan -- Ch 13: What is a green deal without growth, Riccardo Mastini -- Ch 14: Paying a Green New Deal: MMT and the job guarantee, Steven Hall -- Ch 15: The Paradigm Shift, Stephen Williams -- Appendix.
    Abstract: This multidisciplinary book provides new insights and hope for sustainable prosperity given recent developments in economics – but only if swift and strong actions consistent with Earth’s biophysical limits and principles of justice are universally taken. It is one thing to put limits on resource throughput and waste generation to conform with the ecosphere’s biocapacity. It is another thing to efficiently allocate a sustainable rate of resource throughput and ensure it is equitably distributed in the form of final goods and services. While the separate but interdependent decisions regarding throughput, distribution, and allocation are the essence of ecological economics, dealing with them in a world that needs to cure its growth addiction requires a realistic understanding of macroeconomics and the fiscal capacity of currency-issuing central governments. Sustainable prosperity demands that we harness this understanding to carefully regulate the rate of resource throughput and manipulate macroeconomic outcomes to facilitate human flourishing. The book begins by outlining humanity’s current predicament of gross ecological overshoot and laments the half-century of missed opportunities since The Limits to Growth (1972). What was once economic growth has become, in many high-income countries, uneconomic growth (additional costs exceeding additional benefits), which is no longer advancing wellbeing. Meanwhile, low-income nations need a dose of efficient and equitable growth to escape poverty while protecting their environments and the global commons. The book argues for a synthesis of our increasing knowledge of the ecosphere’s limited carrying capacity and the power of governments to harness, transform, and distribute resources for the common good. Central to this synthesis must be a correct understanding of the difference between financial constraints and real resource constraints. While the latter apply to everyone, the former do not apply to currency-issuing central governments, which have much more capacity for corrective action than mainstream thinking perceives. The book joins the growing chorus of authoritative voices calling for a complete overhaul of the dominant economic system. We conclude with policy recommendations based on a new economics that, if implemented, would come close to guaranteeing a sustainable and prosperous future. Upon reading this book, at least one thing should be crystal clear: business as usual is not a viable option.
    Type of Medium: Online Resource
    Pages: VIII, 344 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030787950
    DDC: 500
    Language: English
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  • 4
    Call number: ZSP-124-57
    In: ANARE research notes
    Description / Table of Contents: During the ADBEX III cruise (September to December 1985) to the western Prydz Bay region, Antarctica, nine shallow hauls (0-200 m), six deep hauls (200-1000 m) and one target trawl were made with a RMT 1+8 net, as well as eleven vertical hauls with an ORI-2000 net. From these samples abundance of euphausiids, notably krill Euphausia superba, and other zooplankton was investigated. A diving program was also carried out to observe and collect Euphausia superba from under the pack-ice. For postlarval krill, size (length, weight), sex and maturity composition are reported.
    Type of Medium: Series available for loan
    Pages: iii, 34 S. : Ill.
    ISBN: 0642123977
    Series Statement: ANARE research notes 57
    Branch Library: AWI Library
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  • 5
    Series available for loan
    Series available for loan
    Kingston : Australian National Antarctic Research Expeditions
    Associated volumes
    Call number: ZSP-124-100
    In: ANARE research notes
    Description / Table of Contents: Data relating to hydroxyl airglow observations at Davis Station, on the Antarctic continent, have been collected by the Australian Antarctic Division, and are available in raw digital format for the years 1984, 1987, 1990 and 1994. Future data (1995 and onwards) will become available. The history of the project, instrumental details and the format and coverage of the data are presented.
    Type of Medium: Series available for loan
    Pages: V, 102 S.
    ISBN: 0642253366
    Series Statement: ANARE research notes 100
    Branch Library: AWI Library
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  • 6
    Series available for loan
    Series available for loan
    Kingston : Antarctic Div., Dep. of the Arts, Sport, the Environment, Tourism and Territories
    Associated volumes
    Call number: ZSP-124-75
    In: ANARE research notes
    Description / Table of Contents: Otoliths from 76 fish species are illustrated and described as an aid to the identification of stomach contents of Antarctic birds and mammals. Material was obtained from waters off Australian Antarctic Territory and from around Macquarie and Heard Islands. Information is also given on the distribution, habits and known predators of the fish species.
    Type of Medium: Series available for loan
    Pages: V, 173 S. : zahlr. Ill.
    ISBN: 0642154929
    Series Statement: ANARE research notes 75
    Branch Library: AWI Library
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  • 7
    Series available for loan
    Series available for loan
    Washington, DC : United States Gov. Print. Off.
    Associated volumes
    Call number: S 90.0002(1746)
    In: Professional paper
    Description / Table of Contents: Professional Paper 1746 (this book) is the second of the three books; it is being published in both English and Icelandic editions. This book provides information about all named glaciers in Iceland, historic and modern. Descriptions, with geographic coordinates, and bibliographic citations to all glacier place-names on published maps, books, and scientific articles are included. Maps, oblique aerial photographs, ground photographs, and satellite images document each of the 269 modern named glaciers of Iceland.
    Type of Medium: Series available for loan
    Pages: X, 225, A7 S. , zahlr. Ill., Kt. , 28 cm
    ISBN: 9780607978155
    Series Statement: U.S. Geological Survey professional paper 1746
    Classification:
    Regional Geology
    Location: Lower compact magazine
    Branch Library: GFZ Library
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  • 8
    Series available for loan
    Series available for loan
    Kingston : Antarctic Division, Dept. of Science
    Associated volumes
    Call number: ZSP-124-31
    In: ANARE research notes
    Description / Table of Contents: This report summarises the data on zooplankton collected during the ADBEX I cruise on M. V. Nella Dan during November and December 1982. It includes a station list, description of the nets used, the composition of catches, and some analysis of the catches of Euphausia superba.
    Type of Medium: Series available for loan
    Pages: iv, 108 S. : Ill.
    ISBN: 0642099278
    Series Statement: ANARE research notes 31
    Branch Library: AWI Library
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  • 9
    Call number: 9/M 07.0421(395) ; https://doi.org/10.1144/SP395
    In: Geological Society special publication
    Description / Table of Contents: Humankind has pervasively influenced the Earth's atmosphere, biosphere, geosphere, hydrosphere and cryosphere, arguably to the point of fashioning a new geological epoch, the Anthropocene. To constrain the Anthropocene as a potential formal unit within the Geological Time Scale, a spectrum of indicators of anthropogenically-induced environmental change is considered, and shown as stratigraphical signals that may be used to characterize an Anthropocene unit, and to recognize its base. This volume describes a range of evidence that may help to define this potential new time unit and details key signatures that could be used in its definition. These signatures include lithostratigraphical (novel deposits, minerals and mineral magnetism), biostratigraphical (macro- and micro-palaeontological successions and human-induced trace fossils) and chemostratigraphical (organic, inorganic and radiogenic signatures in deposits, speleothems and ice and volcanic eruptions). We include, finally, the suggestion that humans have created a further sphere, the technosphere, that drives global change.
    Type of Medium: Monograph available for loan
    Pages: 393 Seiten , Illustrationen, Diagramme
    ISBN: 9781862396289
    Series Statement: Geological Society special publication 395
    Classification:
    Historical Geology
    Note: TABLE OF CONTENTS An introduction to the Anthropocene: case for and against a new epoch A stratigraphical basis for the Anthropocene? / Colin N. Waters, Jan A. Zalasiewicz, Mark Williams, Michael A. Ellis and Andrea M. Snelling / Geological Society, London, Special Publications, 395, 1-21, 24 March 2014, https://doi.org/10.1144/SP395.18 The ‘Anthropocene’ as a ratified unit in the ICS International Chronostratigraphic Chart: fundamental issues that must be addressed by the Task Group / S. C. Finney / Geological Society, London, Special Publications, 395, 23-28, 24 October 2013, https://doi.org/10.1144/SP395.9 The term ‘Anthropocene’ in the context of formal geological classification / P. L. Gibbard and M. J. C. Walker / Geological Society, London, Special Publications, 395, 29-37, 25 October 2013, https://doi.org/10.1144/SP395.1 Can an Anthropocene Series be defined and recognized? / Jan Zalasiewicz, Mark Williams and Colin N. Waters / Geological Society, London, Special Publications, 395, 39-53, 10 March 2014, https://doi.org/10.1144/SP395.16 The nature of anthropogenic deposits and landscape modification An assessment of lithostratigraphy for anthropogenic deposits / J. R. Ford, S. J. Price, A. H. Cooper and C. N. Waters / Geological Society, London, Special Publications, 395, 55-89, 8 April 2014, https://doi.org/10.1144/SP395.12 The relationship between archaeological stratigraphy and artificial ground and its significance in the Anthropocene / M. Edgeworth / Geological Society, London, Special Publications, 395, 91-108, 25 October 2013, https://doi.org/10.1144/SP395.3 The mineral signature of the Anthropocene in its deep-time context / Jan Zalasiewicz, Ryszard Kryza and Mark Williams / Geological Society, London, Special Publications, 395, 109-117, 19 December 2013, https://doi.org/10.1144/SP395.2 Geomagnetic and mineral magnetic characterization of the Anthropocene / Ian Snowball, Mark W. Hounslow and Andreas Nilsson / Geological Society, London, Special Publications, 395, 119-141, 19 December 2013, https://doi.org/10.1144/SP395.13 A biostratigraphical signature for the Anthropocene Is the fossil record of complex animal behaviour a stratigraphical analogue for the Anthropocene? / M. Williams, J. A. Zalasiewicz, C. N. Waters and E. Landing / Geological Society, London, Special Publications, 395, 143-148, 25 October 2013, https://doi.org/10.1144/SP395.8 Palaeontological evidence for defining the Anthropocene / Anthony D. Barnosky / Geological Society, London, Special Publications, 395, 149-165, 24 October 2013, https://doi.org/10.1144/SP395.6 Coral reefs in the Anthropocene: persistence or the end of the line? / O. Hoegh-Guldberg / Geological Society, London, Special Publications, 395, 167-183, 20 March 2014, https://doi.org/10.1144/SP395.17 Microbiotic signatures of the Anthropocene in marginal marine and freshwater palaeoenvironments / I. P. Wilkinson, C. Poirier, M. J. Head, C. D. Sayer and J. Tibby / Geological Society, London, Special Publications, 395, 185-219, 31 January 2014, https://doi.org/10.1144/SP395.14 Geochemical signatures and catastrophic events Assessing the Anthropocene with geochemical methods / Agnieszka Gałuszka, Zdzisław M. Migaszewski and Jan Zalasiewicz / Geological Society, London, Special Publications, 395, 221-238, 24 October 2013, https://doi.org/10.1144/SP395.5 Definition of the Anthropocene: a view from the underworld / Ian J. Fairchild and Silvia Frisia / Geological Society, London, Special Publications, 395, 239-254, 24 October 2013, https://doi.org/10.1144/SP395.7 Ice Sheets and the Anthropocene / Eric W. Wolff / Geological Society, London, Special Publications, 395, 255-263, 25 November 2013, https://doi.org/10.1144/SP395.10 The release and persistence of radioactive anthropogenic nuclides / Gary J. Hancock, Stephen G. Tims, L. Keith Fifield and Ian T. Webster / Geological Society, London, Special Publications, 395, 265-281, 28 February 2014, https://doi.org/10.1144/SP395.15 Volcanic markers for dating the onset of the Anthropocene / Victoria C. Smith / Geological Society, London, Special Publications, 395, 283-299, 21 November 2013, https://doi.org/10.1144/SP395.11 The technosphere concept Technology as a geological phenomenon: implications for human well-being / P. K. Haff / Geological Society, London, Special Publications, 395, 301-309, 24 October 2013, https://doi.org/10.1144/SP395.4
    Location: Reading room
    Branch Library: GFZ Library
    Branch Library: GFZ Library
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  • 10
    Monograph available for loan
    Monograph available for loan
    Washington, DC : World Resources Institute
    Call number: MOP 47464 / Mitte
    Type of Medium: Monograph available for loan
    Pages: VII, 123 S. : Ill., Kt.
    ISBN: 0915825384
    Location: MOP - must be ordered
    Branch Library: GFZ Library
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