ISSN:
0030-493X
Keywords:
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Various reactions, intentional or unwanted, between several types of boron-containing compound and multifunctional nucleophilic substrates occurring on the probe tip can be examined in situ by negative-ion fast atom bombardment mass spectrometry (FABMS). Unwanted reactions of spiroborates with common liquid matrices can be avoided by using tetraethylene glycol diethyl ether as solvent for FABMS. Even so, the components of mixtures of spiroborates undergo ligand exchange with each other. Different orientations of hydroxy groups in isomeric diols, hydroxyacids and dicarboxylic acids can be differentiated by reaction on the probe tip with trialkyl borates, producing negatively charged spiroborates, or preferably with dibenzeneborinic acid ethanolamine complex. Successful reaction in the latter case can be assessed by observing the eliminated ethanolamine by positive-ion FABMS and formation of the corresponding negatively charged borate in the negative-ion mode. Potential applications of this methodology are discussed.
Additional Material:
3 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/oms.1210240810
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