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  • 1
    Publication Date: 2022-05-25
    Description: Author Posting. © The Author(s), 2009. This is the author's version of the work. It is posted here by permission of John Wiley & Sons for personal use, not for redistribution. The definitive version was published in Advanced Materials 21 (2009): 401-406, doi:10.1002/adma.200801197.
    Description: Recent interest in the development of environmentally benign routes to the synthesis of novel multifunctional materials has resulted in numerous investigations into structure-function relationships of a wide range of biological systems at the ultrastructural, micromechanical, and biochemical levels. While much of this research has concentrated on mineralized structures such as bone, mollusk shells sponge spicules and echinoderm ossicles, there is an equally broad range of animals whose skeletal structures are devoid of mineral components.One such group, the squids (Mollusca: Cephalopoda: Teuthoidea), are remarkable in several aspects. In addition to having an exceptionally well developed brain, sensory systems and skin (for adaptive coloration), these swift agile predators have eight flexible strong arms, two fast extensible tentacles, and strong malleable suckers, all of which are muscular hydrostats.
    Description: We gratefully acknowledge funding from the Swiss National Science Foundation (AM, PA002–113176 / 1), NIH 5 R01 DE 014672, DANSYNC for supporting the synchrotron experiments, and the Danish Research Councils, as well as partial support (RTH) by DARPA DSO BioDynotics Program (Project N66001-03-C-8043).
    Keywords: Cephalopoda ; Proteinaceous ; Cellular solids ; Biomimetic
    Repository Name: Woods Hole Open Access Server
    Type: Preprint
    Format: application/pdf
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  • 2
    Publication Date: 2022-05-26
    Description: Author Posting. © The Author(s), 2009. This is the author's version of the work. It is posted here by permission of The Royal Society for personal use, not for redistribution. The definitive version was published in Journal of The Royal Society Interface 6 (2010): 549-560, doi:10.1098/rsif.2009.0299.
    Description: Many cephalopods exhibit remarkable dermal iridescence, a component of their complex, dynamic camouflage and communication. In the species Euprymna scolopes, the light-organ iridescence is static and is due to reflectin protein-based platelets assembled into lamellar thin-film reflectors called iridosomes, contained within iridescent cells called iridocytes. Squid in the family Loliginidae appear to be unique in that the dermis possesses a dynamic iridescent component, with reflective, colored structures that are assembled and disassembled under the control of the muscarinic cholinergic system and the associated neurotransmitter acetylcholine (Mathger et al. 2004). Here we present the sequences and characterization of three new members of the reflectin family associated with the dynamically changeable iridescence in Loligo and not found in static Euprymna iridophores. In addition, we show that application of genistein, a protein tyrosine kinase inhibitor, suppresses acetylcholine- and calcium-induced iridescence in Loligo. We further demonstrate that two of these novel reflectins are extensively phosphorylated in concert with the activation of iridescence by exogenous acetylcholine. This phosphorylation and the correlated iridescence can be blocked with genistein. Our results suggest that tyrosine phosphorylation of reflectin proteins is involved in the regulation of dynamic iridescence in Loligo.
    Description: We gratefully acknowledge support from Anteon contract F33615-03-D-5408 to the Marine Biological Laboratory, Woods Hole, MA and grant # W911NF-06-1-0285 from the Army Research Office to D.E.M.
    Repository Name: Woods Hole Open Access Server
    Type: Preprint
    Format: application/pdf
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  • 3
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Analytical chemistry 46 (1974), S. 1878-1879 
    ISSN: 1520-6882
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Analytical chemistry 52 (1980), S. 505-508 
    ISSN: 1520-6882
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Biochemistry 27 (1988), S. 8899-8903 
    ISSN: 1520-4995
    Source: ACS Legacy Archives
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Ground water 40 (2002), S. 0 
    ISSN: 1745-6584
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Geosciences
    Notes: Steady and transient seepage problems were investigated numerically using a dimensionless formulation for water flow in variably saturated, two-dimensional anisotropic and homogenous porous media. The dimensionless formulation combines the aspect ratio and the anisotropy ratio in one dimensionless parameter, M, and accounts for capillarity effects using the ratio of the domain height to the height of capillary fringe as another dimensionless parameter, a. Two domain geometries were considered: rectangular and trapezoidal. It was found that M and a play major roles in the development and the height of the seepage face. The height of the steady-state seepage face increased with the decreasing value of a.The effects of capillarity on the development of the transient seepage face were investigated by lowering the open water level on one side of the domain at various uniform velocities while the other side was kept at a constant value. It was found for most scenarios that decoupling between the water table and the open water level first occurred for domains with large a. In other words, the seepage face heights of these systems were larger than those with a small a. These results are the opposite of the steady-state results and are due to the fact that drainage of the pores was the major mechanism controlling the drop of the transient water table, especially at earlier times.A criterion for the decoupling of the water table from the falling open water level (i.e., the formation of the transient seepage face) was developed by Dracos (1965). It states that decoupling does not occur as long as the falling speed, VF, of the open water level is less than Vd= Ko sin2 B/φ where Ko is the saturated hydraulic conductivity of the soil, φ is the porosity, and β is the angle of the exit face with the horizontal (i.e., β=π/2 implies a vertical face). Our investigation revealed that decoupling occurs for smaller falling velocities than Vd, and is caused by, among others, the fact that the water table is not tangent to the exit face but rather intersects it at a nonzero angle.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Industrial & engineering chemistry 41 (1949), S. 1798-1801 
    ISSN: 1520-5045
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Industrial & engineering chemistry 48 (1956), S. 934-942 
    ISSN: 1520-5045
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Industrial & engineering chemistry 49 (1957), S. 936-946 
    ISSN: 1520-5045
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Industrial & engineering chemistry 50 (1958), S. 753-762 
    ISSN: 1520-5045
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
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