ISSN:
1013-9826
Source:
Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
Topics:
Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
Notes:
Radix salvia miltiorrhiza is a commonly used herbal medicine in China, and tanshinoneIIA is one of the major active ingredients. Nano Radix salvia miltiorrhiza particles were successfullyprepared by high speed centrifugal sheering (HSCS) technology, and the prepared nanoparticlessuspension was subsequently spray-dried. The different properties of nano particles and raw powderwere systematically studied by laser light scattering granulometric analyzer, TEM, SEM and FTIR.The extractive quantity of tanshinone IIA was determined by high-performance liquidchromatography (HPLC). The results illustrate that raw Radix salvia miltiorrhiza powder can beultrafinely ground to nanosize within 50min, and the molecular structure of active ingredients doesn’tchange after being ground. Furthermore, the active ingredients can dissolve out directly and fully, andthe extractive ratio of tanshinone IIA increases 28.6% by HSCS processing. It is valuable to combinenanotechnology and TCM to improve the bioavailability and rapid releasing
Type of Medium:
Electronic Resource
URL:
http://www.tib-hannover.de/fulltexts/2011/0528/01/52/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.330-332.215.pdf
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