ISSN:
0021-8383
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The arylhydrazones of ethyl α-oxo-cyanoacetate 1a-e and the α-arylhydrazones of β-phenyl-α,β-diketopropionitrile 2a-e, react with GRIGNARD reagents at room temperature to yield the cyanocarbinols 3a-h. On the other hand, 1 and 2 react with phenylmagnesium bromide in refluxing ether-benzene mixture, to yield the imino derivatives 4a-d. 3a-e are dehydrated by hot acetic acid to yield compounds 5a-d. Similar treatment of 41-d affords the α-arylazo-β-phenylchalcones 6a-d which react with hydroxylamine to yield isoxazoline derivatives 7a-d.Treatment of 1b, d with ethereal diazomethane results in the formation of the N-methylarylhydrazones 8a, b.The arylhydrazono-malodinitriles 9 react with GRIGNARD reagents to yield the imino derivatives 10.
Additional Material:
1 Tab.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/prac.19723140515
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