Publication Date:
2015-03-01
Description:
Article The need to develop vaccines against pathogens such as HIV requires the development of strategies to overcome inhibitory immunoregulatory mechanisms. Here, the authors report that murine natural killer cells inhibit CD4- and follicular helper T cells, leading to a weaker germinal center response and diminished virus-specific immune memory. Nature Communications doi: 10.1038/ncomms7375 Authors: Carolyn Rydyznski, Keith A. Daniels, Erik P. Karmele, Taylor R. Brooks, Sarah E. Mahl, Michael T. Moran, Caimei Li, Rujapak Sutiwisesak, Raymond M. Welsh, Stephen N. Waggoner
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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